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Researchers identify new biomarker and therapeutic target for pancreatic cancer

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently no reliable method for early detection or therapeutic intervention. The paper will be published May 15 in Cancer Research.

15 May 2012

MicroRNA-3151 a new independent prognostic marker for acute leukemia

A study has identified microRNA-3151 as a new independent prognostic marker in certain patients with acute leukemia. The study involves patients with acute myeloid leukemia and normal-looking chromosomes.

15 May 2012

Excess protein in urine test predicts renal failure in patients with severe sepsis

Henry Ford Hospital researchers have found that the presence of excess protein in a common urine test is an effective prognostic marker of acute renal failure in patients with severe sepsis.

14 May 2012

Eggs for breakfast associated with greater satiety and reduced calorie consumption

New research presented at the 19th European Congress on Obesity in Lyon, France reports that eating eggs for breakfast is associated with greater satiety and reduced calorie consumption at lunch than eating wheat-based breakfast foods like ready-to-eat breakfast cereal. Participants in the study reported feeling fuller following the egg breakfast and tests of their hunger hormone levels supported their self-reported observations.

14 May 2012

Soligenix first quarter revenues decrease to $647,418

Soligenix, Inc., a development stage biopharmaceutical company, announced today its financial results for the quarter ending March 31, 2012.

14 May 2012

mTOR protein plays a key role in development of diabetes

The signaling protein mTOR is a key regulator that controls cell growth. Dysfunction of mTOR increases not only the likelihood of developing cancer but also diabetes. In the current issue of the journal Cell Metabolism, Mike Hall and his team from the Biozentrum of the University of Basel describe how inhibition of mTOR signaling can impair carbohydrate metabolism and potentially lead to diabetes.

14 May 2012

Safety tips to prevent heat-related illness

The National Weather Service reports that heat is the number one cause of weather-related deaths, killing approximately 400 Americans each year.

14 May 2012

Researchers uncover new way to stimulate activity of immune cell opiate receptors

Researchers at Rutgers University have uncovered a new way to stimulate activity of immune cell opiate receptors, leading to efficient tumor cell clearance.

14 May 2012

Diet tips on how to stay healthy this summer

Warmer temperatures mean a lot of time spent outdoors and at social functions - both of which can offer plenty of opportunity to indulge in your favorite foods. Sadly, these frequent splurges also lead to an expanding waistline.

14 May 2012

Naked mole rat's proteasome assemblies differ in composition from other short-lived rodents

The naked mole rat, a curiously strange, hairless rodent, lives many years longer than any other mouse or rat. Scientists at The University of Texas Health Science Center San Antonio's Barshop Institute of Longevity and Aging Studies continue to explore this mystery.

14 May 2012

Study describes new compounds that inhibit PRMT1 enzyme

Scientists at The Scripps Research Institute have found the first chemical compounds that act to block an enzyme that has been linked to inflammatory conditions such as asthma and arthritis, as well as some inflammation-promoted cancers.

11 May 2012

'Packing problem' could have a solution for cancer treatment

A hidden facet of a math problem that goes back to Sanskrit scrolls has just been exposed by nanotechnology researchers at the University of Michigan and the University of Connecticut.

11 May 2012

Chromatin compaction required for proper embryonic stem cell differentiation

New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: differentiation into specific cell types that give rise to the various types of tissues and structures in the body.

11 May 2012

Lot of fat and few carbohydrates could have better effect on blood sugar levels, lipids in diabetics

People with Type 2 diabetes are usually advised to keep a low-fat diet. Now, a study at Linköping University shows that food with a lot of fat and few carbohydrates could have a better effect on blood sugar levels and blood lipids.

11 May 2012

Final results from Alnylam’s ALN-TTR01 Phase I trial on TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today final results from its completed Phase I clinical trial with ALN-TTR01, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis.

11 May 2012

Researchers identify over 2500 mRNA along dendrites and axons

How do we build a memory in the brain? It is well known that for animals (and humans) new proteins are needed to establish long-term memories. During learning information is stored at the synapses, the junctions connecting nerve cells.

11 May 2012

RNP granules exit the nucleus via new budding mechanism akin to herpes-type viruses

New evidence published in Cell by Vivian Budnik, PhD, Melissa J. Moore, PhD, and colleagues at the University of Massachusetts Medical School, reveals a novel budding mechanism, similar to the process used by some viruses, capable of exporting large ribonucleoprotein particles from the nucleus to the cytoplasm.

11 May 2012

Maternal gluten sensitivity may increase risk of schizophrenia in children

Babies born to women with sensitivity to gluten appear to be at increased risk for certain psychiatric disorders later in life, according to research by scientists at Karolinska Institutet in Sweden and Johns Hopkins Children's Center in Baltimore.

11 May 2012

Rituximab does not appear to benefit children with INS

The drug rituximab, an antibody that targets the immune system and is often used to treat immune disorders such as lymphoma and arthritis, has recently emerged as a potential treatment for a childhood kidney disorder known as idiopathic nephrotic syndrome.

11 May 2012

Researchers discover protein that regulates activation of brown fat

Scientists have identified a protein which regulates the activation of brown fat in both the brain and the body's tissues. Their research, which was conducted in mice, was published today, Friday 11 May, in the journal Cell.

11 May 2012

G Protein News and Research

Researchers identify new biomarker and therapeutic target for pancreatic cancer

MicroRNA-3151 a new independent prognostic marker for acute leukemia

Excess protein in urine test predicts renal failure in patients with severe sepsis

Eggs for breakfast associated with greater satiety and reduced calorie consumption

Soligenix first quarter revenues decrease to $647,418

mTOR protein plays a key role in development of diabetes

Safety tips to prevent heat-related illness

Researchers uncover new way to stimulate activity of immune cell opiate receptors

Diet tips on how to stay healthy this summer

Naked mole rat's proteasome assemblies differ in composition from other short-lived rodents

Study describes new compounds that inhibit PRMT1 enzyme

'Packing problem' could have a solution for cancer treatment

Chromatin compaction required for proper embryonic stem cell differentiation

Lot of fat and few carbohydrates could have better effect on blood sugar levels, lipids in diabetics

Final results from Alnylam’s ALN-TTR01 Phase I trial on TTR-mediated amyloidosis

Researchers identify over 2500 mRNA along dendrites and axons

RNP granules exit the nucleus via new budding mechanism akin to herpes-type viruses

Maternal gluten sensitivity may increase risk of schizophrenia in children

Rituximab does not appear to benefit children with INS

Researchers discover protein that regulates activation of brown fat

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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