Immune System News and Research

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Research provides new insight into how coevolution could shape microbial diversity in human gut

What drives bacterial strain diversity in the gut? Although there are a number of possible explanations, a recent opinion piece published in TRENDs in Microbiology by Dr Pauline Scanlan, a Royal Society - Science Foundation Ireland Research Fellow at the APC Microbiome Institute, University College Cork, addresses one potentially important and overlooked aspect of this unresolved question.

28 Mar 2017

Rogue proteins involved in breast cancer point to potential treatment options

For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies.

28 Mar 2017

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Scientists from Tomsk Polytechnic University together with their colleagues from St. Petersburg and London have elaborated a new approach to deliver anti-viral RNAi to target cells against H1N1 influenza virus infection.

28 Mar 2017

Public-private collaboration to develop more accurate methods of tracking cancer progression

Columbia University Medical Center and NewYork-Presbyterian, in coordination with the Foundation for the National Institutes of Health Biomarkers Consortium, is launching a three-year research collaboration to develop new methods for analyzing digital images that track a patient's response to cancer therapy.

28 Mar 2017

New probiotic may help combat negative health effects of adrenaline surges

U.S. sailors and Marines face continuous periods of excessive stress in "fight-or-flight" situations, triggering surges of chemical messengers called neurotransmitters, often known as an adrenaline rush.

28 Mar 2017

Researchers map key Zika virus protein to accelerate search for cure

A study published today shows how Indiana University scientists are speeding the path to new treatments for the Zika virus, an infectious disease linked to birth defects in infants in South and Central America and the United States.

28 Mar 2017

Research findings offer potential explanation for opioid-induced itching

Opioids have long been an important tool in the world of pain management, but the side effects of these drugs - from addiction and respiratory failure to severe itching and dizziness, can be overwhelming.

27 Mar 2017

3U researchers discover biological marker that could predict development of Type 1 diabetes

A significant finding has been made by the 3U Diabetes Consortium, of Dublin City University, Maynooth University and the Royal College of Surgeons in Ireland, which has the potential to contribute to the identification of biological markers that predict the development of Type 1 diabetes, a chronic autoimmune disease.

27 Mar 2017

Disease of antiquity: University of Notre Dame expert focuses on tuberculosis research

In the time it takes to read this article, half a dozen people will have died from tuberculosis. It is a cruel and persistent killer, claiming 1.8 million lives each year, an estimated 200,000 of which are children, according to the World Health Organization.

27 Mar 2017

UVA researchers discover unexpected interaction between men's testes and immune system

The University of Virginia School of Medicine has again shown that a part of the body thought to be disconnected from the immune system actually interacts with it, and that discovery helps explain cases of male infertility, certain autoimmune diseases and even the failure of cancer vaccines.

25 Mar 2017

Combination of high-intensity ultrasound and immunotherapy may be effective in treating cancer

In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer.

25 Mar 2017

Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

The U.S. Food and Drug Administration yesterday granted accelerated approval to the checkpoint inhibitor Bavencio (avelumab) for the treatment of patients with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

25 Mar 2017

Exposure to acrolein causes failure of immune defence to tumours, study finds

The World Health Organisation estimates that every year 600,000 deaths are caused by passive smoking worldwide and, in Austria alone, two or three people a day die as a result of passive smoking.

25 Mar 2017

Scientists discover potential role for 'jumping genes' in ALS

By inserting an amyotrophic lateral sclerosis (ALS)-linked human gene called TDP-43 into fruit flies, researchers at Stony Brook University and Cold Spring Harbor Laboratory discovered a potential role for 'transposons' in the disease.

24 Mar 2017

Review provides new understanding of cytokine mediated effects on inflammatory disorders

Researchers studying chronic inflammation that can lead to the development of lung diseases such as asthma, pulmonary fibrosis, and cancer, are focusing on the role cytokines play in regulating the behavior of fibroblast cells and the extracellular matrix.

24 Mar 2017

One-shot vaccine passes key preclinical test in newborn monkey models

Newborns are highly vulnerable to infections and don't respond optimally to most vaccines because their young immune systems typically mount weak antibody responses.

24 Mar 2017

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes.

24 Mar 2017

New research reveals surprising culprit involved in self-destruction of axons

In many neurodegenerative conditions — Parkinson's disease, amyotrophic lateral sclerosis (ALS) and peripheral neuropathy among them — an early defect is the loss of axons, the wiring of the nervous system.

24 Mar 2017

FDA grants accelerated approval to new drug for treatment of rare form of skin cancer

The U.S. Food and Drug Administration today granted accelerated approval to Bavencio (avelumab) for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

23 Mar 2017

Researchers unravel how drug interacts with ribosome to halt protein production

The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins before they are even made.

23 Mar 2017

Immune System News and Research

Research provides new insight into how coevolution could shape microbial diversity in human gut

Rogue proteins involved in breast cancer point to potential treatment options

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Public-private collaboration to develop more accurate methods of tracking cancer progression

New probiotic may help combat negative health effects of adrenaline surges

Researchers map key Zika virus protein to accelerate search for cure

Research findings offer potential explanation for opioid-induced itching

3U researchers discover biological marker that could predict development of Type 1 diabetes

Disease of antiquity: University of Notre Dame expert focuses on tuberculosis research

UVA researchers discover unexpected interaction between men's testes and immune system

Combination of high-intensity ultrasound and immunotherapy may be effective in treating cancer

Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

Exposure to acrolein causes failure of immune defence to tumours, study finds

Scientists discover potential role for 'jumping genes' in ALS

Review provides new understanding of cytokine mediated effects on inflammatory disorders

One-shot vaccine passes key preclinical test in newborn monkey models

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

New research reveals surprising culprit involved in self-destruction of axons

FDA grants accelerated approval to new drug for treatment of rare form of skin cancer

Researchers unravel how drug interacts with ribosome to halt protein production

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