Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Klotho proteins important players in future therapies for diabetes, obesity and kidney disease

A relative of the anti-aging gene Klotho helps activate a hormone that can lower blood glucose levels in fat cells of mice, making it a novel target for developing drugs to treat human obesity and diabetes, UT Southwestern Medical Center researchers have found.

24 Apr 2007

Why bladder cancer hits more men than women

Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease.

21 Apr 2007

Long-term survival probability in men with clinically localized prostate cancer

Randomized studies comparing conservative therapy to definitive therapy in men with prostate cancer (CaP) are underway, but not yet available.

20 Apr 2007

Jefferson participates in global study to extend effectiveness of drug for Parkinson's

After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication that controls muscle movement by replacing lost dopamine, they begin to experience motor complications that include a shortened response to each dose of L-dopa.

19 Apr 2007

New understanding of genetics behind Noonan Syndrome

Researchers have discovered that the genetic malfunction that causes a form of mental retardation called Noonan Syndrome (NS) produces an imbalance in the genesis of two types of cells in the developing embryonic brain.

19 Apr 2007

Researchers observer proteins important in Alzheimer's, Parkinson's moving along axons

Using a novel video-imaging system, researchers at the University of Pennsylvania School of Medicine have been able to observe proteins important in Alzheimer's and Parkinson's disease moving along axons, extensions of nerve cells that carry proteins away from the cell body.

18 Apr 2007

Martek's DHA algal oil reduces brain lesions in Alzheimer's animal model

Martek's proprietary DHA algal oil may slow the development of two brain lesions that are hallmarks of Alzheimer's disease, according to a study featured in the April 18 issue of the Journal of Neuroscience.

18 Apr 2007

Omega-3 fatty acid may help prevent brain lesions

A type of omega-3 fatty acid may slow the growth of two brain lesions that are hallmarks of Alzheimer's disease, UC Irvine scientists have discovered.

18 Apr 2007

Bacteria barge inside guard cells and initiate a powerful immune response

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought.

18 Apr 2007

New vaccine strategy for head and neck cancers

Most attempts to create therapeutic cancer vaccines are based on custom-made approaches that use a patient's own tumor cells to generate a strong immune response against cancer.

18 Apr 2007

Scientists tackle cancer with different approaches

Studies presented at the 2007 meeting of the American Association for Cancer Research show how researchers are using the new, as well as the natural, to help design and test new drugs to treat cancer.

18 Apr 2007

Silver Award for advances in the prevention of HIV perinatal transmission

The Children's Hospital of Philadelphia presented J. Brooks Jackson, M.D., MBA, of Johns Hopkins University with the Herman and Gertrude Silver Award for his internationally prominent work in preventing the transmission of HIV from infected mothers to their newborn babies.

17 Apr 2007

Most-at-risk nursing home residents to be tested for superbugs

A Johns Hopkins study of adult patients admitted to The Johns Hopkins Hospital showed that patients who resided in nursing homes or other kinds of long-term care facilities at any time within the last six months were far more likely than other adult patients to carry or be infected with a drug-resistant superbug.

17 Apr 2007

Johns Hopkins to test all children for 'superbugs'

Infection control and critical care experts at The Johns Hopkins Hospital have ordered testing for the two most common hospital superbugs for every child admitted to its pediatric intensive care unit.

17 Apr 2007

New genetic risk factors for Crohn's disease

An international research team , including investigators from Massachusetts General Hospital (MGH) and the Broad Institute of Harvard University and Massachusetts Institute of Technology, has identified several novel genetic variations associated with the risk of Crohn's disease.

16 Apr 2007

Report on radical prostatectomy for octogenarians

There is no defined recommendation for when to stop prostate cancer (CaP) screening, except when the life expectancy decreases to less than 10 years.

16 Apr 2007

Astrocytes may contribute to Lou Gehrig's disease

Two papers by Columbia and Harvard researchers report for the first time that astrocytes (the most abundant non-neuronal cells in the central nervous system), which carry a mutated gene known to cause some cases of amyotrophic lateral sclerosis (ALS/Lou Gehrig's disease), induce motor neuron death.

16 Apr 2007