Clinical Trial News and Research

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LAMA/LABA combination better than monotherapy for severe COPD

Combination treatment with umeclidinium bromide and vilanterol offers clinically meaningful improvements over tiotropium monotherapy for patients with moderate-to-very severe chronic obstructive pulmonary disease, study data show.

31 Oct 2014

Data reveals sustained local control for early stage lung cancer patients who receive SBRT

Analysis of data from an institutional patient registry on stereotactic body radiotherapy (SBRT) indicates excellent long-term, local control, 79 percent of tumors, for medically inoperable, early stage lung cancer patients treated with SBRT from 2003 to 2012, according to research presented today at the 2014 Chicago Multidisciplinary Symposium in Thoracic Oncology.

31 Oct 2014

Dosing of antiretroviral medication to prevent HIV infection differs by sex

A mathematical model developed by NIH grantees predicts that women must take the antiretroviral medication Truvada daily to prevent HIV infection via vaginal sex, whereas just two doses per week can protect men from HIV infection via anal sex.

31 Oct 2014

FDA recommens approval of Daiichi Sankyo's once-daily SAVAYSA for patients with NVAF

Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced that the U.S. Food and Drug Administration's Cardiovascular and Renal Drugs Advisory Committee voted 9 to 1 to recommend approval of once-daily SAVAYSA (edoxaban) 60 mg dosing regimen for the reduction in risk of stroke and systemic embolic events (SEE) in patients with non-valvular atrial fibrillation (NVAF).

30 Oct 2014

Neurocrine Biosciences' NBI-98854 drug gets breakthrough designation for tardive dyskinesia

Neurocrine Biosciences, Inc. announced today that the U.S. Food and Drug Administration has granted Breakthrough Therapy Designation for its Vesicular Monoamine Transporter 2 inhibitor, NBI-98854, in tardive dyskinesia.

30 Oct 2014

Auxilium Pharmaceuticals reports total revenues of $109.6 million for Q3 2014

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced financial results for the third quarter ending September 30, 2014.

30 Oct 2014

KCR adopts Veeva Systems’ cloud-based content management solution to improve operations

KCR, a European Contract Research Organization operating across 19 European countries and in the US, has turned to the cloud in a move to improve cross-functional collaboration and trial operations. KCR will replace the mix of paper and file-share solutions used to manage trial master files with Veeva Systems’ cloud-based content management solution, Veeva Vault.

29 Oct 2014

Rapamycin and dasatinib combination may be beneficial in treating breast cancer, say scientists

The uncontrolled growth of cancer cells arises from their ability to hijack the cell’s normal growth program and checkpoints. Usually after therapy, a second cancer-signaling pathway will open after the primary one shuts down — creating an ingenious escape route for the cancer cell to survive. The answer, say Case Western Reserve researchers, is to anticipate and block that back-up track by prescribing two drugs from the start.

29 Oct 2014

Japanese mushroom extract shows promise in eradicating HPV

A Japanese mushroom extract appears to be effective for the eradication of human papillomavirus (HPV), according to a pilot clinical trial at The University of Texas Health Science Center at Houston Medical School.

29 Oct 2014

QT Medical partners with LA BioMed to identify infants at risk of long QT syndrome

Each year, some 2,000 babies are born in the U.S. with a genetic heart condition, known as long QT syndrome. If not diagnosed in time, babies with long QT syndrome can die from a sudden arrhythmia, or irregular heartbeat.

29 Oct 2014

Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

Scientists at the Roskamp Institute, a not-for-profit biomedical research facility specializing in Alzheimer's disease research, have isolated a key molecule that gives researchers a new drug target for the treatment of the progressive, irreversible neurological disorder.

28 Oct 2014

RPC1063 drug candidate has potential to improve treatment for ulcerative colitis patients

Positive new clinical data were released today on a drug candidate for ulcerative colitis that was first discovered and synthesized at The Scripps Research Institute.

28 Oct 2014

PlasmaTech Biopharmaceuticals inks agreement to commercialize MuGard in Australia, New Zealand

PlasmaTech Biopharmaceuticals, Inc., a biopharmaceutical company advancing patient care in critical areas, has entered into an exclusive license agreement with Norgine B.V., a European specialist pharmaceutical company, for the commercialization of MuGard in Australia and New Zealand.

27 Oct 2014

Understanding of genomic landscape of thyroid cancer

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients.

27 Oct 2014

Researchers receive EPSRC grant to develop real-time diagnostic technique for dementia

A research team from Plymouth University, together with colleagues from Swansea University, has received funding of £1M from the Engineering and Physical Sciences Research Council to develop an innovative, real-time diagnostic technique for dementia using wonder-material graphene.

27 Oct 2014

MPI Research announces acquisition of Jasper Clinical Research & Development

MPI Research today announced it has acquired the assets of Kalamazoo, Mich.-based Jasper Clinical Research & Development, Inc. Jasper is a respected clinical research organization that provides early-stage human clinical testing of promising new drugs, and is well known to pharmaceutical and biotechnology companies worldwide.

27 Oct 2014

Enhanced dental care reduces respiratory tract infection risk in ICU patients

New research shows vulnerable patients in the Intensive Care Unit (ICU) who received enhanced oral care from a dentist were at significantly less risk for developing a lower respiratory tract infection (LRTI), like ventilator-associated pneumonia, during their stay.

25 Oct 2014

Aseptika launches Contactless Thermometer and Pulse Oximeter

With the winter flu and cold season almost upon us we can stock up and take some steps to prepare at home for this eventuality. Having a flu jab, eating well, getting lots of exercise and sleep, and maintain good personal hygiene all help in preventing flu and colds.

23 Oct 2014

Human trial of second investigational Ebola vaccine candidate under way

Human testing of a second investigational Ebola vaccine candidate is under way at the National Institutes of Health's Clinical Center in Bethesda, Maryland.

23 Oct 2014

Regulus Therapeutics demonstrates human proof-of-concept with microRNA therapeutic

Regulus Therapeutics Inc. (NASDAQ:RGLS), a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that it has demonstrated human proof-of-concept with a microRNA therapeutic from an ongoing clinical study evaluating RG-101, a wholly-owned, GalNac-conjugated anti-miR targeting microRNA-122 (“miR-122”), for the treatment of hepatitis C virus infection (“HCV”).

22 Oct 2014

Clinical Trial News and Research

LAMA/LABA combination better than monotherapy for severe COPD

Data reveals sustained local control for early stage lung cancer patients who receive SBRT

Dosing of antiretroviral medication to prevent HIV infection differs by sex

FDA recommens approval of Daiichi Sankyo's once-daily SAVAYSA for patients with NVAF

Neurocrine Biosciences' NBI-98854 drug gets breakthrough designation for tardive dyskinesia

Auxilium Pharmaceuticals reports total revenues of $109.6 million for Q3 2014

KCR adopts Veeva Systems’ cloud-based content management solution to improve operations

Rapamycin and dasatinib combination may be beneficial in treating breast cancer, say scientists

Japanese mushroom extract shows promise in eradicating HPV

QT Medical partners with LA BioMed to identify infants at risk of long QT syndrome

Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

RPC1063 drug candidate has potential to improve treatment for ulcerative colitis patients

PlasmaTech Biopharmaceuticals inks agreement to commercialize MuGard in Australia, New Zealand

Understanding of genomic landscape of thyroid cancer

Researchers receive EPSRC grant to develop real-time diagnostic technique for dementia

MPI Research announces acquisition of Jasper Clinical Research & Development

Enhanced dental care reduces respiratory tract infection risk in ICU patients

Aseptika launches Contactless Thermometer and Pulse Oximeter

Human trial of second investigational Ebola vaccine candidate under way

Regulus Therapeutics demonstrates human proof-of-concept with microRNA therapeutic

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