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Researchers discover new mechanism involving p53 to fight against aggressive cancers

Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers.

20 Sep 2013

Human breast tumors transplant could be valuable tools in search for better treatments

Breast cancer that spreads to other organs is extremely difficult to treat. Doctors can buy patients time, but a cure remains elusive. Now, researchers at Washington University School of Medicine in St. Louis have shown that human breast tumors transplanted into mice are excellent models of metastatic cancer and could be valuable tools in the search for better treatments.

20 Sep 2013

Study sheds new light on the dark matter of genome

Using technology he helped develop, Vanderbilt University scientist Bryan Venters, Ph.D., has shed new light on the "dark matter" of the genome and has begun to explore a possible new approach to treating cancer.

19 Sep 2013

Johns Hopkins establishes center to study ELSI of applying genomics to infectious disease treatment

The National Human Genome Research Institute has selected the Johns Hopkins Berman Institute of Bioethics to establish a "Center of Excellence" to study the ethical, legal and social implications of genomic research.

19 Sep 2013

Sequenom announces Certified Service Provider program for technical certification

Sequenom, Inc., a life sciences company providing innovative diagnostic testing and genetic analysis solutions, today announced a Certified Service Provider (CSP) program for the technical certification of selected laboratories offering research services using the Sequenom research-use-only MassARRAY System.

18 Sep 2013

Mayo Clinic to host annual Individualizing Medicine Conference from Sept. 30 to Oct. 2

From Promise to Practice is the title and the main message of the second annual Individualizing Medicine Conference at Mayo Clinic, Sept. 30-Oct. 2. Physicians from more than 40 states and several countries will be arriving in Minnesota to hear and learn about the latest developments and research in genomic research and how to move these discoveries into the medical practice.

18 Sep 2013

Study reveals that composition of skin microbiota is controlled by host genome

Numerous recent studies linked gut microbiota with various diseases such as obesity or diabetes. Little is known, however, on how gut and skin microbiota composition is controlled.

18 Sep 2013

Understanding essential role of gut microbes in immune system

A new understanding of the essential role of gut microbes in the immune system may hold the key to dealing with some of the more significant health problems facing people in the world today, Oregon State University researchers say in a new analysis.

17 Sep 2013

Researchers identify potentially treatable subtype of pancreatic cancer

Australian researchers have identified a potentially treatable subtype of pancreatic cancer, which accounts for about 2% of new cases. This subtype expresses high levels of the HER2 gene. HER2-amplified breast and gastric cancers are currently treated with Herceptin.

17 Sep 2013

Gentris expands genomic biomarker offering with launch of Affymetrix GeneChip HTA services

Gentris Corporation, a global leader in pharmacogenomics and biorepository solutions, announced today that it is expanding its genomic biomarker offering with the launch of Affymetrix GeneChip Human Transcriptome Array services.

17 Sep 2013

Researchers identify gene mutation linked to age-related macular degeneration

An international team of researchers, led by scientists at The Genome Institute at Washington University School of Medicine in St. Louis and the University of Michigan School of Public Health in Ann Arbor, has identified a gene mutation linked to age-related macular degeneration (AMD), the leading cause of blindness in Americans over age 50.

17 Sep 2013

Studying Tumor Mutations Via A Network Approach

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16 Sep 2013

New approach subtypes cancers by shared genetic effects; a step toward personalized medicine

Cancer tumors almost never share the exact same genetic mutations, a fact that has confounded scientific efforts to better categorize cancer types and develop more targeted, effective treatments.

16 Sep 2013

Domestic animals less likely to be major source of antibiotic resistant Salmonella in humans

A new study has shown that, contrary to popular belief, local domestic animals are unlikely to be the major source of antibiotic resistant Salmonella in humans. The result comes from a detailed study of DNA from more than 370 Salmonella samples collected over a 22-year period.

13 Sep 2013

Researchers show network of genes which enforce cooperative state within cells

We often think of human cells as tiny computers that perform assigned tasks, where disease is a result of a malfunction. But in the current issue of Science, researchers at The Mount Sinai Medical Center offer a radical view of health — seeing it more as a cooperative state among cells, while they see disease as result of cells at war that fight with each other for domination.

13 Sep 2013

Viewpoints: GOP 'obsession' with health law prevents progress on key financial issues; the 'fantasy of fertility;' VA is 'model' for transforming U.S. medicine

Try as they might, House Republican leaders are having trouble stopping their colleagues from shooting themselves in the foot -- again. Having failed to approve any of the 12 annual appropriations bills that fund federal agencies, Congress has to pass a stopgap spending bill by Sept. 30 to keep much of the federal government from shutting down.

13 Sep 2013

Pancreatic protein essential for maintaining functional state of beta cells

Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 - a beta-cell enriched transcription factor - is essential to maintaining the functional state of beta cells.

13 Sep 2013

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

Since the sequence map of the human genome, the cost of sequencing the genome of an individual has fallen rapidly. This has resulted in a tremendous increase in the amount of human genomic data available to the international research community for the advancement of biomedical research. Yet, there is an absence of international mechanisms to support researchers in ensuring ethical and legal interoperability. In addition, the multiplicity and diversity of laws, standards and policies on sharing and accessing genetic and medical data represent major hurdles to international collaboration.

12 Sep 2013

Mount Sinai physician-scientists join DILIN to help find causes, diagnostics for drug-induced liver injury

In an effort to better understand and develop prevention strategies for drug-induced liver injury, physician-scientists from the Icahn School of Medicine at Mount Sinai have joined the Drug-Induced Liver Injury Network, a National Institutes of Health-funded consortium of only six academic medical centers in the United States.

12 Sep 2013

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report today in Nature Communications.

12 Sep 2013

Genome News and Research

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Human breast tumors transplant could be valuable tools in search for better treatments

Study sheds new light on the dark matter of genome

Johns Hopkins establishes center to study ELSI of applying genomics to infectious disease treatment

Sequenom announces Certified Service Provider program for technical certification

Mayo Clinic to host annual Individualizing Medicine Conference from Sept. 30 to Oct. 2

Study reveals that composition of skin microbiota is controlled by host genome

Understanding essential role of gut microbes in immune system

Researchers identify potentially treatable subtype of pancreatic cancer

Gentris expands genomic biomarker offering with launch of Affymetrix GeneChip HTA services

Researchers identify gene mutation linked to age-related macular degeneration

Studying Tumor Mutations Via A Network Approach

New approach subtypes cancers by shared genetic effects; a step toward personalized medicine

Domestic animals less likely to be major source of antibiotic resistant Salmonella in humans

Researchers show network of genes which enforce cooperative state within cells

Viewpoints: GOP 'obsession' with health law prevents progress on key financial issues; the 'fantasy of fertility;' VA is 'model' for transforming U.S. medicine

Pancreatic protein essential for maintaining functional state of beta cells

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

Mount Sinai physician-scientists join DILIN to help find causes, diagnostics for drug-induced liver injury

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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