Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Chemotherapy following radiation therapy improves survival for adults with brain tumor

Adults with low-grade gliomas, a form of brain tumor, who received a chemotherapy regimen following completion of radiation therapy, lived longer than patients who received radiation therapy alone, according to long-term follow-up results from a National Institutes of Health-supported randomized controlled clinical trial.

6 Feb 2014

Incyte enters into clinical trial collaboration agreement with Merck to evaluate safety of IDO1 inhibitor

Incyte Corporation (Nasdaq: INCY) announced today that it has entered into a clinical trial collaboration agreement with Merck, through a Merck subsidiary, to evaluate the safety and efficacy of Incyte's oral indoleamine dioxygenase-1 (IDO1) inhibitor, INCB24360, and Merck's investigational anti-PD-1 immunotherapy, MK-3475, in a Phase I/II study in previously treated metastatic and recurrent non-small cell lung cancer (NSCLC), and other advanced or metastatic cancers.

5 Feb 2014

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Pfizer Inc. announced today that it has agreed with Merck & Co., Inc., known as MSD outside the United States and Canada ("Merck"), through two Merck subsidiaries, to explore the therapeutic potential of Merck's investigational anti-PD-1 therapy, MK-3475, in combination with two Pfizer oncology assets.

5 Feb 2014

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

Patients with diabetes are at increased risk of microvascular complications, which develop when the body's small blood vessels become diseased. One of the most common problems results when wounds fail to heal properly, which can lead to ulcers, chronic infections, and in the most serious cases, limb amputations.

5 Feb 2014

MORE intervention reduces pain and opioid misuse

With nearly one-third of Americans suffering from chronic pain, prescription opioid painkillers have become the leading form of treatment for this debilitating condition. Unfortunately, misuse of prescription opioids can lead to serious side effects-including death by overdose.

5 Feb 2014

Healthcare experts propose concrete steps for managing shortages of life-saving drugs

A group of prominent healthcare experts including bioethicists, pharmacists, policymakers and cancer specialists have proposed concrete steps for preventing and managing a nightmare scenario that is becoming all too common: shortages of life-saving drugs.

4 Feb 2014

Pfizer’s palbociclib Phase 2 trial achieves primary endpoint in patients with advanced breast cancer

Pfizer Inc. today announced that the randomized Phase 2 trial [PALOMA-1] of palbociclib achieved its primary endpoint by demonstrating a statistically significant and clinically meaningful improvement in progression-free survival (PFS) for the combination of palbociclib and letrozole compared with letrozole alone in post-menopausal women with estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) locally advanced or newly diagnosed metastatic breast cancer.

4 Feb 2014

Cancer specialist takes efforts to improve survival rates across Europe

Queen's University Belfast's world renowned cancer specialist, Professor Patrick Johnston, whose work has transformed cancer care in Northern Ireland, is now leading efforts to improve survival rates across Europe.

4 Feb 2014

Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found a chemical "signature" in blood-forming stem cells that predicts whether patients with acute myeloid leukemia (AML) will respond to chemotherapy.

4 Feb 2014

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Researchers from Virginia Commonwealth University (VCU) Massey Cancer Center have discovered a new signaling pathway in sterile inflammation that could impact the treatment of diseases such as cancer, multiple sclerosis and rheumatoid arthritis.

4 Feb 2014

Personalized messages over phone can help catch cancer at earliest stages

Although the field of science keeps advancing, it may be the simple telephone that helps save more lives. Anita Kinney, Professor of Medicine and Associate Director for Population Sciences at the University of New Mexico Cancer Center, and her fellow researchers have found that personalized messages over the phone can better help promote preventive measures against cancer.

4 Feb 2014

Children who received radiation as part of treatment may have lower long-term survival rates, says study

The first comprehensive, large-scale cohort study of the long-term survival of children treated for low-grade gliomas, the most common pediatric brain tumor, finds that almost 90 percent are alive 20 years later and that few die from the tumor as adults.

4 Feb 2014

Nearly half of HIV-infected teenagers, young adults forego treatment

Nearly half of HIV-infected teenagers and young adults forego timely treatment, delaying care until their disease has advanced, which puts them at risk for dangerous infections and long-term complications, according to a study led by the Johns Hopkins Children's Center.

4 Feb 2014

IDH1 gene mutation determines best treatment for malignant astrocytomas

Astrocytomas are the most common malignant brain tumors. While most patients' tumors prove to be quite aggressive, outcomes overall can vary widely, with some patients surviving for many years.

4 Feb 2014

Putnam Hospital Center recognized with CEO Cancer Gold Standard accreditation

Putnam Hospital Center in Carmel, NY, is leading by example when it comes to promoting healthy lifestyle choices and encouraging workplace wellness. The CEO Roundtable on Cancer has accredited Putnam Hospital Center with the CEO Cancer Gold Standard recognizing the firm's efforts to reduce the risk of cancer for its employees and covered family members by establishing programs to reduce cancer risk, encouraging early detection through cancer screenings, and ensuring access to quality treatment.

3 Feb 2014

Mylan launches trastuzumab biosimilar for treatment of HER2-positive metastatic breast cancer

Mylan Inc. (Nasdaq: MYL), one of the world's leading generic and specialty pharmaceutical companies, today announced that its subsidiary, Mylan Pharmaceuticals Private Limited, has launched the world's first trastuzumab biosimilar in India.

3 Feb 2014

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Researchers in the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute discovered in pre-clinical models that dormant prostate cancer cells found in bone tissue can be reawakened, causing metastasis to other parts of the body. Understanding this mechanism of action may allow researchers to intervene prior to disease progression.

31 Jan 2014

Cleveland Browns makes University Hospitals as official health care partner

Today, the Cleveland Browns made official the partnership that makes University Hospitals in Cleveland the official health care partner of the Cleveland Browns for the next 10 years.

31 Jan 2014

New study reveals way to combat drug-resistant tumors

Cancer drugs that recruit antibodies from the body's own immune system to help kill tumors have shown much promise in treating several types of cancer. However, after initial success, the tumors often return.

31 Jan 2014

Study describes new tack in treatment of lung adenocarcinomas

The most common genetic subtype of lung cancer, which has long defied treatment with targeted therapies, has had its growth halted by a combination of two already-in-use drugs in laboratory and animal studies, setting the stage for clinical trials of the drugs in patients, researchers at Dana-Farber Cancer Institute and other scientists report in a new study.

31 Jan 2014

Oncology News and Research

Further Reading

Chemotherapy following radiation therapy improves survival for adults with brain tumor

Incyte enters into clinical trial collaboration agreement with Merck to evaluate safety of IDO1 inhibitor

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

MORE intervention reduces pain and opioid misuse

Healthcare experts propose concrete steps for managing shortages of life-saving drugs

Pfizer’s palbociclib Phase 2 trial achieves primary endpoint in patients with advanced breast cancer

Cancer specialist takes efforts to improve survival rates across Europe

Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Personalized messages over phone can help catch cancer at earliest stages

Children who received radiation as part of treatment may have lower long-term survival rates, says study

Nearly half of HIV-infected teenagers, young adults forego treatment

IDH1 gene mutation determines best treatment for malignant astrocytomas

Putnam Hospital Center recognized with CEO Cancer Gold Standard accreditation

Mylan launches trastuzumab biosimilar for treatment of HER2-positive metastatic breast cancer

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Cleveland Browns makes University Hospitals as official health care partner

New study reveals way to combat drug-resistant tumors

Study describes new tack in treatment of lung adenocarcinomas

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