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Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

“IDPs” is now a widely used acronym that stands for “intrinsically disordered proteins.” It is the term generally used by the scientific community to refer to a wide variety of proteins that do not have a stable 3D structure and are instead characterized by a high extent of local mobility, disorder and many conformers that are accessible at room temperature.

From Bruker BioSpin Division 30 Jun 2016

Unwelcoming healthcare environments may affect cervical cancer screening among LGBT people

A new study found that certain factors affect cervical cancer screening among lesbian and bisexual women and transgender men. Some of these factors overlap with the general female population, whereas others are specific to the lesbian, bisexual, or queer identity.

30 Jun 2016

Breakthrough research could lead to new drugs to improve heart attack outcomes

A research advance from the Sanford Burnham Prebys Medical Discovery Institute and Stanford University could lead to new drugs that minimize the damage caused by heart attacks.

30 Jun 2016

Excess or insufficient sleep may increase diabetes risk in men

Men who sleep either fewer or more hours than average may face a greater risk of developing diabetes, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

30 Jun 2016

New research identifies flaws in LM-method for Lyme disease

A new microscopy technique (LM-method) developed to detect Lyme disease is unable to distinguish infected patients from healthy controls, yielding false-positive results that could lead doctors to over-diagnose a patient, according to new research published in the journal Infectious Diseases.

30 Jun 2016

Researchers develop 2D culture system that mimics development of the whole eye

Research groups led by Professor Kohji Nishida of the Department of Ophthalmology and Endowed Associate Professor Ryuhei Hayashi of the Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, developed a 2D culture system which mimics the development of the whole eye by promoting cell-autonomous differentiation of human iPS cells.

30 Jun 2016

Study highlights continuing problem of MSI in Gulf War veterans

Veterans of the Gulf War are more than twice as likely to have medically unexplained symptoms known as "multisymptom illness" (MSI), compared to Iraq/Afghanistan War veterans, according to an updated research review in the July Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine.

30 Jun 2016

Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Venuprasad Poojary, PhD, an associate investigator at Baylor Institute for Immunology Research (BIIR), part of Baylor Scott & White Research Institute, reported this week in the journal Nature Immunology the role of a key protein in the regulatory pathway that is involved in limiting colon inflammation and tumor growth.

30 Jun 2016

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors.

30 Jun 2016

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

The Perelman School of Medicine at the University of Pennsylvania has launched a new program, called AAV 3.0, to create new viral vectors to find quicker and better treatments for an array of diseases. James M. Wilson, MD, PhD, a professor of Medicine and director of the Orphan Disease Center, will lead an interdisciplinary team of over 30 scientists to create this new technology platform with support provided by the University of Pennsylvania Health System.

30 Jun 2016

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses.

30 Jun 2016

Surgeons outline complete face transplant procedure in facial burn patients

Last year, the most extensive clinical face transplant to date was successfully carried out at NYU Langone Medical Center.

30 Jun 2016

Google Glass shows promising plastic surgical application in operating room

Plastic surgeons see some clear advantages of using Google Glass in the operating room, reports a survey study in the July issue of Plastic and Reconstructive Surgery,the official medical journal of the American Society of Plastic Surgeons.

30 Jun 2016

Experts compile model list of essential diagnostic tests aiming to improve global health

In a western doctor's office or hospital, patients don't think twice about giving a blood or urine sample that can tell if they have a disease or infection, or show if their medicines are working. The samples get rushed to a testing lab with modern equipment that's held to high quality standards.

30 Jun 2016

UTHealth researchers receive $11 million grant to study prion diseases

Led by Claudio Soto, Ph.D., researchers from McGovern Medical School at The University of Texas Health Science Center at Houston have been awarded $11 million from the National Institute of Allergy and Infectious Diseases to study the pathogenesis, transmission and detection of prion diseases - such as chronic wasting disease in deer - that can potentially spread to humans.

30 Jun 2016

Stem cell procedure may be safe for ALS patients

A phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, suggests that transplanting human stem cells into the spinal cord may be done safely.

30 Jun 2016

Study links alpha-defensin genes to IgA nephropathy risk

A gene which forms part of our body's first line of defence against infection may be associated with an increased risk with a type of kidney disease, research involving academics at The University of Nottingham has discovered.

30 Jun 2016

Scientists reveal metabolic reasons why low calorie diets may lead to longer life

Overeating can lead to health issues that can shorten one's life, such as obesity, diabetes and heart disease.

30 Jun 2016

Testosterone therapy improves sexual activity in older men

Older men with low libido and low testosterone levels showed more interest in sex and engaged in more sexual activity when they underwent testosterone therapy, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

30 Jun 2016

Researchers find main cause of necrotizing enterocolitis-related lung damage in preemies

Johns Hopkins researchers report they have figured out a root cause of the lung damage that occurs in up to 10 percent of premature infants who develop necrotizing enterocolitis, a disorder that damages and kills the lining of the intestine.

29 Jun 2016

Research News and Research

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

Unwelcoming healthcare environments may affect cervical cancer screening among LGBT people

Breakthrough research could lead to new drugs to improve heart attack outcomes

Excess or insufficient sleep may increase diabetes risk in men

New research identifies flaws in LM-method for Lyme disease

Researchers develop 2D culture system that mimics development of the whole eye

Study highlights continuing problem of MSI in Gulf War veterans

Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Study focuses on critical proteins involved in ovarian cancer biology

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Surgeons outline complete face transplant procedure in facial burn patients

Google Glass shows promising plastic surgical application in operating room

Experts compile model list of essential diagnostic tests aiming to improve global health

UTHealth researchers receive $11 million grant to study prion diseases

Stem cell procedure may be safe for ALS patients

Study links alpha-defensin genes to IgA nephropathy risk

Scientists reveal metabolic reasons why low calorie diets may lead to longer life

Testosterone therapy improves sexual activity in older men

Researchers find main cause of necrotizing enterocolitis-related lung damage in preemies

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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