Inflammation News and Research

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Outcome of ACL reconstruction related to the way you move post-surgery

A third of people who undergo ACL reconstruction surgery will have osteoarthritis in their injured knee within 10 years. Within two decades, nearly 50 percent will -- terrible odds for getting a debilitating condition with no known cure.

18 Sep 2018

Lymphatic vessels surrounding the brain play crucial role in multiple sclerosis, research suggests

Lymphatic vessels that clean the brain of harmful material play a crucial role in the development and progression of multiple sclerosis, new research from the University of Virginia School of Medicine suggests.

18 Sep 2018

Targeted Lung Denervation procedure significantly reduces COPD problems

First results from a clinical trial of a procedure to open obstructed airways in patients with chronic obstructive pulmonary disease have shown that it significantly reduces problems associated with the disease and is safe.

18 Sep 2018

Resveratrol decreases pain severity and levels of inflammatory biomarkers in osteoarthritis patients

In what researchers state is the first pilot clinical trial to assess the effects of resveratrol on pain severity and levels of inflammatory biomarkers in patients with mild to moderate knee osteoarthritis, the scientists compared treatment with a nonsteroidal anti-inflammatory drug combined with either resveratrol or placebo over 90 days.

18 Sep 2018

Women with undiagnosed STIs may be at greater risk of negative premenstrual symptoms

Women that have undiagnosed sexually transmitted infections may be at greater risk of experiencing negative premenstrual symptoms, according to new Oxford University research.

17 Sep 2018

Researchers develop new blood test to detect early stage pancreatic cancer

Pancreatic cancer is currently very difficult to detect while it is still resectable. A new blood test developed by researchers at Lund University in Sweden, Herlev Hospital, Knight Cancer Center and Immunovia AB, can detect pancreatic cancer in the very earliest stages of the disease.

17 Sep 2018

Easy and rapid test for viral infections can cut antibiotic use, hospitalizations

A quick and easy test for viral infections can reduce unnecessary antibiotic use and hospital admissions, according to new research presented to the European Respiratory Society International Congress today.

17 Sep 2018

Paracetamol use in infancy may increase risk of developing asthma by the age of 18

Children who take paracetamol during their first two years of life may be at a higher risk of developing asthma by the age of 18, especially if they have a particular genetic makeup, according to new research presented at the European Respiratory Society International Congress today.

17 Sep 2018

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers at Northeast Ohio Medical University studied the lifespan of mitochondrial proteins in a mouse model of fatty liver disease. Comparing the amount of protein between healthy mice and a mouse model of nonalcoholic fatty liver disease gave them an estimate of each protein's half-life.

17 Sep 2018

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer.

14 Sep 2018

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis, a chronic and aggressive liver condition.

14 Sep 2018

Study could pave way for new therapies to reverse aging in human cells

Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age.

14 Sep 2018

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

Many eye diseases, including diabetic retinopathy and macular degeneration, exhibit increased permeability of blood vessels in the macular (central) portion of the retina leading to abnormal fluid accumulation and vision loss.

14 Sep 2018

Obesity changes airway muscle function, raises asthma risk

New research suggests that obesity changes how airway muscles function, increasing the risk of developing asthma. The study is published ahead of print in the American Journal of Physiology--Lung Cellular and Molecular Physiology.

14 Sep 2018

Dietary fiber may delay memory loss, brain inflammation during old age

As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function.

14 Sep 2018

Breakthrough shows immune cells may play a role in schizophrenia

A type of immune cell called the “macrophages” are known to be one of the first soldiers of the body that can fight off infections and plays a role in maintaining immunity and in inflammation. According to latest research in schizophrenia, these macrophages can become altered and may cause changes in the brain leading to changes in the brain similar to schizophrenia.

14 Sep 2018

Blood serum induces spontaneous movement and growth of skin cells

What happens to skin cells when they are confronted with blood? A team of researchers from Oslo University Hospital, led by Emma Lång and Stig Ove Bøe, performed experiments on blood-deprived cells that were subsequently exposed to blood serum.

13 Sep 2018

Pear-shaped body is healthier than apple shape

Whether we like it or not, everyone accumulates fat. For women, it usually accumulates around the hips, resulting in a pear-shaped look. In men, fat tends to build up around the abdomen, creating an apple shape.

13 Sep 2018

Cellular environment affects type of tumor development

Liver cancer is the second leading cause of cancer death worldwide. Two different forms of primary liver cancer cover the majority of cases: About 10 to 20 percent of those affected develop a bile duct carcinoma within the liver (intrahepatic cholangiocellular carcinoma; ICC), the far higher proportion of liver cancers are hepatocellular carcinomas.

12 Sep 2018

Alivio Therapeutics receives DoD grant to advance development of new therapy for IC/BPS

Alivio Therapeutics, an affiliate of PureTech Health plc developing therapies to treat inflammatory disorders through targeted disease immunomodulation, today announced a $3.3 million U.S. Department of Defense Technology/Therapeutic Development Award to advance Alivio's product candidate, ALV-107, for the treatment of interstitial cystitis/bladder pain syndrome with Hunner's lesions.

12 Sep 2018

Inflammation News and Research

Outcome of ACL reconstruction related to the way you move post-surgery

Lymphatic vessels surrounding the brain play crucial role in multiple sclerosis, research suggests

Targeted Lung Denervation procedure significantly reduces COPD problems

Resveratrol decreases pain severity and levels of inflammatory biomarkers in osteoarthritis patients

Women with undiagnosed STIs may be at greater risk of negative premenstrual symptoms

Researchers develop new blood test to detect early stage pancreatic cancer

Easy and rapid test for viral infections can cut antibiotic use, hospitalizations

Paracetamol use in infancy may increase risk of developing asthma by the age of 18

New studies examine links between fatty liver disease and mitochondrial dysfunction

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Study could pave way for new therapies to reverse aging in human cells

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

Obesity changes airway muscle function, raises asthma risk

Dietary fiber may delay memory loss, brain inflammation during old age

Breakthrough shows immune cells may play a role in schizophrenia

Blood serum induces spontaneous movement and growth of skin cells

Pear-shaped body is healthier than apple shape

Cellular environment affects type of tumor development

Alivio Therapeutics receives DoD grant to advance development of new therapy for IC/BPS

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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