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UMass Amherst scientists delve into the mysteries of how cells manage stress

In new research recently published in the journal Cell Reports, a team of scientists from the University of Massachusetts Amherst delved into the mysteries of how cells weather stress.

28 Sep 2022

Study reveals how pathogens exploit a key cellular process to intoxicate cells

What our work shows is how a complex in the center of the cell, the ER-Golgi interaction region, controls plasma membrane cholesterol, which is essential for many cellular functions, if not essential for multicellular life.

28 Sep 2022

Changes in temperature may be behind the link between circadian disruption and cancer

Disruptions in circadian rhythm - the ways that our bodies change in response to the 24-hour light and dark cycle - have been linked to many different diseases, including cancer.

28 Sep 2022

Researchers find new way to deliver a protein quickly, effectively and briefly to the brain

Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively and briefly to the brain, with therapeutic and scientific implications.

28 Sep 2022

Exploring biological mechanisms behind the link between obesity prior to pregnancy and elevated risk of pediatric ALL

Published in Leukemia Research, University of Minnesota Medical School researchers explored the possible biological mechanisms that could explain the association between being overweight or obese prior to pregnancy and the increased risk of acute lymphoblastic leukemia (ALL) in children.

28 Sep 2022

Scientists visualize antibiotics in action inside a pathogenic bacterium

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival.

28 Sep 2022

Insights into the biology of virtual memory CD8+ T cells

Virtual memory CD8+ T cells (TVM) are a relatively recent discovery in humans. A new review discusses what is known about them from mouse models and their cellular equivalents in humans, as described in the peer-reviewed Journal of Interferon & Cytokine Research.

28 Sep 2022

Treatment for neurological diseases often no longer effective enough in the later stages

Neurological diseases often begin with an inflammatory process and the degradation of the so-called myelin layer, which surrounds the nerve fibers (axons) like a protective insulating layer.

28 Sep 2022

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

Like bacteria, yeasts are found everywhere, even in and around our bodies. And, as with bacteria, you can become infected by yeasts and become ill. Yeasts infect about 150 million people a year and kill about 1.7 million, especially those who are immunocompromised.

28 Sep 2022

Vitamin supplements can benefit cystic fibrosis patients, study suggests

Cystic fibrosis patients who supplement their diet with vitamin C can also derive greater benefit from another antioxidant, vitamin E, resulting in a reduction in damaging inflammation, a study led by Oregon State University suggests.

28 Sep 2022

Shape-shifting mitochondria influence Th17 cells’ propensity for autoimmune activity

A new study focused on the immune system's Th17 cells suggests that the shape and function of their mitochondria (the powerhouse of cells) is important in autoimmune and inflammatory disorders, such as multiple sclerosis.

28 Sep 2022

New compound triggers the same anti-depressant action as rapidly acting psychedelic drugs

While illegal for recreational use, psychedelic drugs are showing great promise as treatments for severe depression and anxiety, as well as alcohol addiction and other conditions.

28 Sep 2022

New Zika vaccine technology found to be highly effective and safe in preclinical mouse models

Researchers from the University of California, Los Angeles have developed a Zika vaccine technology that is highly effective and safe in preclinical mouse models.

28 Sep 2022

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

A new study showed that SARS-CoV-2 Spike N-glycosylation patterns, intracellular lectins, and the associated molecular chaperones play crucial roles in the viral-host-cell invasion and function.

28 Sep 2022

Live imaging and cellular barcoding reveal how new stem cells are vetted for quality

Using live imaging and cellular barcoding, researchers in the Stem Cell Program at Boston Children's Hospital have glimpsed how new stem cells - in this case, blood stem cells - are vetted for quality soon after they're born.

28 Sep 2022

Researchers computationally design immunogens to elicit antibodies against different SARS-CoV-2 variants

A recent study designed immunogens to induce antibodies against SARS-CoV-2 variants.

28 Sep 2022

Can the gut be an alternative route for SARS-CoV-2 entry?

Researchers reviewed the gut pathophysiology of SARS-CoV-2 infection.

28 Sep 2022

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

New Jersey Institute of Technology researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based drugs, such as therapeutic monoclonal antibodies being developed to treat a variety of diseases, from cancers to infectious diseases.

27 Sep 2022

Bile acids play an important role in regulating gut microbiome

Scientists performe in vitro and in vivo experiments to investigate the antimicrobial effects of different bile acids on various microorganisms.

27 Sep 2022

How the gut microbiome could affect COVID-19 severity

Researchers review the potential role of the gut microbiome in determining severe COVID-19.

27 Sep 2022

B Cell News and Research

UMass Amherst scientists delve into the mysteries of how cells manage stress

Study reveals how pathogens exploit a key cellular process to intoxicate cells

Changes in temperature may be behind the link between circadian disruption and cancer

Researchers find new way to deliver a protein quickly, effectively and briefly to the brain

Exploring biological mechanisms behind the link between obesity prior to pregnancy and elevated risk of pediatric ALL

Scientists visualize antibiotics in action inside a pathogenic bacterium

Insights into the biology of virtual memory CD8+ T cells

Treatment for neurological diseases often no longer effective enough in the later stages

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

Vitamin supplements can benefit cystic fibrosis patients, study suggests

Shape-shifting mitochondria influence Th17 cells’ propensity for autoimmune activity

New compound triggers the same anti-depressant action as rapidly acting psychedelic drugs

New Zika vaccine technology found to be highly effective and safe in preclinical mouse models

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

Live imaging and cellular barcoding reveal how new stem cells are vetted for quality

Researchers computationally design immunogens to elicit antibodies against different SARS-CoV-2 variants

Can the gut be an alternative route for SARS-CoV-2 entry?

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

Bile acids play an important role in regulating gut microbiome

How the gut microbiome could affect COVID-19 severity

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