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New low-cost technique helps profile dynamic metabolic features from single isogenic cells

Researchers with the Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, have developed a fast, low-cost and high-throughput technique capable of profiling dynamic metabolic features from just one isogenic sample of cells.

1 Sep 2021

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

After over a century of development, cancer immunotherapy (CIT) has risen to become a promising approach for treating cancer. Unlike conventional methods that try to kill cancer cells directly, CIT involves modifying or stimulating the immune system's natural ability to fight the disease. So far, various CIT treatments have shown remarkable results in terms of survival rates, and many new and combination strategies are currently under study.

1 Sep 2021

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy.

31 Aug 2021

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Liquid biopsies detect tumor DNA in blood or urine samples. Two studies led by Washington University School of Medicine in St. Louis describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors.

31 Aug 2021

Blood test could enable early detection of cancer in people with neurofibromatosis type 1

People with an inherited condition known as neurofibromatosis type 1, or NF1, often develop non-cancerous, or benign, tumors that grow along nerves. These tumors can sometimes turn into aggressive cancers, but there hasn't been a good way to determine whether this transformation to cancer has happened.

31 Aug 2021

Telemedicine appointments reduce risk of further illness in children with medical complexity

Telemedicine appointments combined with in-person visits significantly reduced the risk of further illness for children with medically complex cases, according to results of a new study by researchers with The University of Texas Health Science Center at Houston.

31 Aug 2021

$1.3 million in NIH funding to enable drug delivery technology research

Two National Institute of Health grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences at Binghamton University, State University of New York, is the Principal Investigator on both grants - $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.

31 Aug 2021

Study uses novel technology to map the brain circuitry of spirituality

Scientists have long suspected that religiosity and spirituality could be mapped to specific brain circuits, but the location of those circuits remains unknown. Now, a new study using novel technology and the human connectome, a map of neural connections, has identified a brain circuit that seems to mediate that aspect of our personality. The work appears in Biological Psychiatry, published by Elsevier.

31 Aug 2021

Indoor air is an important source of exposure to harmful forever chemicals, study shows

The air we breathe in our homes, schools, and workplaces can be polluted with harmful PFAS chemicals, according to a study published today in Environmental Science & Technology Letters.

31 Aug 2021

New research has implications for developing cancer therapies targeting mutant p53 protein

The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation.

31 Aug 2021

Telehealth’s limits: Battle over state lines and licensing threatens patients’ options

If you live in one state, does it matter that the doctor treating you online is in another? Surprisingly, the answer is yes, and the ability to conduct certain virtual appointments may be nearing an end.

31 Aug 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Severe COVID-19 negatively impacts kidney function in kidney transplant recipients

During her medical school career, third-year student Skylar Nahi has taken advantage of the mentorship and research opportunities available to Feinberg students.

31 Aug 2021

Novel coating technology increases lifespan and stability of implantable devices

Various human implantable medical devices have been developed in recent years, and they are being used in clinical filed. These devices include brain–machine interfaces, in which a chip is implanted into the brain to enable humans to move machines using only their thoughts, and deep brain stimulators for treating Parkinson's disease and other brain diseases.

31 Aug 2021

Sustained and effective response to Janssen COVID-19 vaccine Is enhanced by delayed booster

A new study adds to the data on the optimum interval between the first and second doses of the adenovirus vectored COVID-19 vaccine.

30 Aug 2021

Development of extra protective broad-spectrum antimicrobial face shield

In a new study available on the preprint server Preprints*, researchers have innovated a transparent face shield with intrinsic antimicrobial activity.

30 Aug 2021

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Self-amplifying RNA (saRNA) is an advanced platform for nucleic acid vaccine development. The backbone is typically derived from an alphaviral genome and encodes a gene of interest (GOI) and a viral replicase that can amplify the genomic and subgenomic RNA.

30 Aug 2021

Exercise reduces the amount of calories burned at rest in obese people, study finds

Exercise reduces the amount of calories burned at rest in people with obesity, according to a new study by researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences and the University of Roehampton.

28 Aug 2021

Researchers test remotely operated implantable drug delivery devices on the ISS

From Novartis to Lamborghini, Alessandro Grattoni and the Houston Methodist Research Institute have partnered with big names to leverage the International Space Station U.S. National Laboratory for space-based research and technology development with important benefits back on Earth.

28 Aug 2021

Airflow optimization reduces time required to remove particulate matter from the classroom

According to the WHO, about 7 million people die each year due to air pollution. Particulate matter (PM) triggers inflammatory responses in the human body, causing asthma and other respiratory and cardiovascular diseases. It is more fatal for young and growing students. The Korea Institute of Civil Engineering and Building Technology (KICT) has reduced time required to remove particulate matter from the classroom by more than 30% by optimizing the locations of supply and return diffusers for air supplied into the classroom.

28 Aug 2021

Technology News and Research

New low-cost technique helps profile dynamic metabolic features from single isogenic cells

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Blood test could enable early detection of cancer in people with neurofibromatosis type 1

Telemedicine appointments reduce risk of further illness in children with medical complexity

$1.3 million in NIH funding to enable drug delivery technology research

Study uses novel technology to map the brain circuitry of spirituality

Indoor air is an important source of exposure to harmful forever chemicals, study shows

New research has implications for developing cancer therapies targeting mutant p53 protein

Telehealth’s limits: Battle over state lines and licensing threatens patients’ options

The tale of mRNA vaccines: Turning calamity into opportunity

Severe COVID-19 negatively impacts kidney function in kidney transplant recipients

Novel coating technology increases lifespan and stability of implantable devices

Sustained and effective response to Janssen COVID-19 vaccine Is enhanced by delayed booster

Development of extra protective broad-spectrum antimicrobial face shield

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Exercise reduces the amount of calories burned at rest in obese people, study finds

Researchers test remotely operated implantable drug delivery devices on the ISS

Airflow optimization reduces time required to remove particulate matter from the classroom

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