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Antibiotic combination effective against drug-resistant Pseudomonas

Two well known and used antibiotics when combined have been found to be more effective against a deadly bacteria Pseudomonas aeruginosa, a common cause of hospital-based infections.

8 Jul 2019

New drug combination found to be effective against uveal melanoma in preclinical studies

Uveal melanoma is a very aggressive type of melanoma that affects the eye. It is a rare disorder, affecting an estimated 2,500 people in the United States each year.

8 Jul 2019

Common cold virus strain could be a breakthrough in bladder cancer treatment

Scientists in the UK have found a new way to treat bladder cancer, using a strain of one of the viruses that cause the common cold. The virus is called Coxsackie virus CVA21, and it was found to be oncolytic, or tumor-destroying.

8 Jul 2019

Ludwig Cancer Research study discovers new cellular oxygen sensor

A Ludwig Cancer Research study led by Peter Ratcliffe and colleagues has discovered a previously overlooked oxygen sensor in animal cells that functions very much like one used by plants.

5 Jul 2019

Scientists create powerful method for 'directed evolution' of molecules

UNC School of Medicine scientists created a powerful new "directed evolution" technique for the rapid development of scientific tools and new treatments for many diseases.

5 Jul 2019

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Fábio Almeida describes how NMR can be used to elucidate protein structure and how this data can be applied to human disease.

From Bruker BioSpin Group 4 Jul 2019

Study reveals first complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism.

4 Jul 2019

Combining aerobic exercise and resistance training helps obese older adults preserve muscle mass

As obesity increases in aging Western populations, frailty—which is exacerbated by obesity—is becoming a greater health concern and a major healthcare cost.

4 Jul 2019

Researchers completely eliminate all traces of HIV from infected mice

For the first time, researchers have successfully removed HIV-1 DNA from the genomes of living animals, a critical step towards a potential cure for the disease.

4 Jul 2019

Advances in artificial intelligence could shed light on aging process

There are two kinds of age: chronological age, w hich is the number of years one has lived, and biological age, which is influenced by our genes, lifestyle, behavior, the environment and other factors.

4 Jul 2019

Researchers reveal virulence regulatory mechanism in a superbug

As antibiotic resistance is growing and posing a threat on public health, developing new antibiotics has become more urgent than ever.

4 Jul 2019

Mice study suggests potential treatment approach for MS in humans

For decades medical researchers have known that an effective way to combat multiple sclerosis (MS) would be to suppress the human immune system, since the debilitating disease is caused by the immune system 'mistakenly' attacking tissues in the spine and brain.

3 Jul 2019

Blood pressure medication associated with increased risk of diverticulosis

A type of blood pressure lowering medication, called a calcium-channel blocker, may be linked with an increased risk of a type of bowel condition called diverticulosis.

3 Jul 2019

Targeted treatment offers symptom relief for patients with psychosis

Treatment for individuals who experience psychosis, such as hallucinations and delusions as a result of a psychiatric illness, can be targeted to a specific structural mutation, according to a study published by researchers from McLean Hospital and other institutions in the journal Biological Psychiatry.

3 Jul 2019

Some people treated for type 1 diabetes may have monogenic diabetes, study finds

A Joslin Diabetes Center study among people treated for type 1 diabetes for many years has discovered that a minority may have monogenic diabetes, a non-autoimmune inherited condition that in some cases does not require insulin treatment.

3 Jul 2019

A short bout of exercise improves brain function, study reveals

Most people know that regular exercise is good for your health. New research shows it may make you smarter, too.

3 Jul 2019

Individual variation in genes alters our ability to regulate emotions

A new study in marmoset monkeys suggests that individual variation in genes alters our ability to regulate emotions, providing new insights that could help in the development of personalized therapies to tackle anxiety and depression.

3 Jul 2019

A non-coding RNA may play major role in memory formation

You could call this a neat discovery. Researchers at the University of Alabama at Birmingham have found that a tissue-specific, non-coding RNA called NEAT1 has a major, previously undescribed role in memory formation.

3 Jul 2019

Machine learning model accurately classifies the stages of bladder cancer

The invasive and expensive diagnosis process of bladder cancer, which is one of the most common and aggressive cancers in the United States, may be soon helped by a novel non-invasive diagnostic method thanks to advances in machine learning research at the San Diego Supercomputer Center, Moores Cancer Center, and CureMatch Incorporated.

3 Jul 2019

Antibiotics can wipe out early flu resistance, study finds

Antibiotics can leave the lung vulnerable to flu viruses, leading to significantly worse infections and symptoms, finds a new study in mice led by the Francis Crick Institute.

From The Francis Crick Institute 2 Jul 2019