Clinical Trial News and Research

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Prompt administration of alteplase treatment reduces disability in stroke patients

Many more stroke patients could benefit from thrombolytic treatment (the use of drugs to break up or dissolve blood clots), but it needs to be administered as quickly as possible after the first signs of illness, according to new findings from the largest meta-analysis to date investigating the clot-busting drug alteplase.

7 Aug 2014

RSAM, Rettsyndrome.org renew commitment to defeat Rett syndrome

Rett Syndrome Association of Massachusetts and Rettsyndrome.org are thrilled to announce today their renewed commitment to work together to defeat Rett syndrome. A generous $150,000 donation from RSAM will support a Rettsyndrome.org approved grant to Dr. Michela Fagiolini's project at the Boston Children's Hospital: "Assessing NMDA receptor (NMDAr) modulators to ameliorate cortical regression in Rett syndrome".

7 Aug 2014

Findings show how galectin-1 protein plays key role in high grade malignant gliomas

Brain tumors fly under the radar of the body's defense forces by coating their cells with extra amounts of a specific protein, new research shows.

7 Aug 2014

Researchers take major step forward in developing real ALS treatments

A series of studies begun by Harvard Stem Cell Institute scientists eight years ago has lead to a report published today that may be a major step forward in the quest to develop real treatments for amyotrophic lateral sclerosis, ALS, or Lou Gehrig's disease.

7 Aug 2014

CSSi President Chris Trizna honored as one of PharmaVOICE 100

CSSi, the leader in patient recruitment solutions for the clinical research industry, announced today that President Chris Trizna has been honored as one of the PharmaVOICE 100, an annual list from PharmaVOICE magazine of the most inspiring people in the life-sciences industry.

6 Aug 2014

Research shows how bacteria in airways can help each other replenish vital iron

The body's assailants are cleverer than previously thought. New research from Lund University in Sweden shows for the first time how bacteria in the airways can help each other replenish vital iron.

5 Aug 2014

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Blood sugar surges - after-meal glucose "spikes" - can be life threatening for the 29 million Americans with diabetes. Diabetic blood sugar spikes have been linked to cardiovascular disease, cancer, Alzheimer's disease, kidney failure, and retinal damage.

5 Aug 2014

Repurposed drug used to treat ovarian cancer gives positive results

A repurposed drug originally used to treat ovarian cancer saw positive results for patients with advanced peritoneal cancers during a phase I clinical trial at The University of Kansas Cancer Center.

5 Aug 2014

Drug used for treating rheumatoid arthritis can improve health of kidney transplant recipients

UC San Francisco is the lead institution on a new seven-year, $17 million multicenter study funded by the National Institutes of Health to determine if certain immune system cells and/or a drug now used for treating rheumatoid arthritis can be effective in improving and maintaining the long-term health of kidney transplant recipients.

5 Aug 2014

New clinical trial tests use of gold nanoparticles for treating solid tumors in dogs and cats

When Michael and Sandra Friedlander first came to the Virginia-Maryland College of Veterinary Medicine three years ago with their dog, Grayton, they learned some bad news: Grayton had nasal adenocarcinoma, a form of cancer with a short life expectancy.

5 Aug 2014

PCI agrees to acquire Penn Pharma

Packaging Coordinators, Inc. is pleased to announce it has finalized its agreement to acquire Penn Pharmaceutical Services Limited (Penn Pharma).

4 Aug 2014

Phase 3 ASPIRE clinical trial meets primary endpoint of progression-free survival

Amgen and its subsidiary, Onyx Pharmaceuticals, Inc., today announced that a planned interim analysis demonstrated that the Phase 3 clinical trial ASPIRE (CArfilzomib, Lenalidomide, and DexamethaSone versus Lenalidomide and Dexamethasone for the treatment of PatIents with Relapsed Multiple MyEloma) met its primary endpoint of progression-free survival (PFS).

4 Aug 2014

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Neuralstem, Inc. announced that the final patient was treated in its Phase II trial using NSI-566 spinal cord-derived neural stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

4 Aug 2014

Clinical trial to look for genetic information in cancer patients

Sanford Health is working to enroll approximately 50 adult patients whose cancer has progressed after the first line of treatment or who have rare cancers without standard treatment options in a clinical trial to look for genetic information that could help customize treatment options.

4 Aug 2014

Columbia Laboratories reports 44% year-over-year decrease in CRINONE product revenues

Columbia Laboratories, Inc. today announced financial results for the three and six-month periods ended June 30, 2014.

31 Jul 2014

Genae establishes offices in London to provide high quality research services on global scale

genae, a global Contract Research Organization (CRO) and services provider for the medical industries, announced today the incorporation of genae UK in London.

31 Jul 2014

Researchers to develop global database on situation and evolution of Chagas disease

The Centre for Development Cooperation (CCD) and several research groups of the Universitat Politècnica de Catalunya (UPC) are working together with the World Health Organization (WHO) to develop a global database on the situation and evolution of Chagas disease.

31 Jul 2014

Statin therapy may speed up wound healing following cardiac surgery

Statin therapy may help to improve wound healing in patients following cardiac surgery and reduce overall recovery time, especially in patients who are prone to healing complications, according to a review article in the August 2014 issue of The Annals of Thoracic Surgery.

31 Jul 2014

Naltrexone may be effective in diminishing ICD symptoms in PD patients, study finds

Up to 20 percent of Parkinson's disease (PD) patients and their families may confront a common but largely unrecognized challenge: the occurrence of impulse control disorders (ICDs) such as compulsive gambling, sexual behavior, eating, or spending.

31 Jul 2014

UK researcher working to develop online tool to help patients navigate lung cancer screening decision

The phrase "we caught it early" is possibly the best news a patient can hear in the midst of a cancer diagnosis. Combating cancer in its earliest stages, when the disease is localized to a certain part of the body, gives patients the best chances of survival.

31 Jul 2014

Clinical Trial News and Research

Prompt administration of alteplase treatment reduces disability in stroke patients

RSAM, Rettsyndrome.org renew commitment to defeat Rett syndrome

Findings show how galectin-1 protein plays key role in high grade malignant gliomas

Researchers take major step forward in developing real ALS treatments

CSSi President Chris Trizna honored as one of PharmaVOICE 100

Research shows how bacteria in airways can help each other replenish vital iron

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Repurposed drug used to treat ovarian cancer gives positive results

Drug used for treating rheumatoid arthritis can improve health of kidney transplant recipients

New clinical trial tests use of gold nanoparticles for treating solid tumors in dogs and cats

PCI agrees to acquire Penn Pharma

Phase 3 ASPIRE clinical trial meets primary endpoint of progression-free survival

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Clinical trial to look for genetic information in cancer patients

Columbia Laboratories reports 44% year-over-year decrease in CRINONE product revenues

Genae establishes offices in London to provide high quality research services on global scale

Researchers to develop global database on situation and evolution of Chagas disease

Statin therapy may speed up wound healing following cardiac surgery

Naltrexone may be effective in diminishing ICD symptoms in PD patients, study finds

UK researcher working to develop online tool to help patients navigate lung cancer screening decision

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