Efficacy News and Research

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Dealing with nail fungus: Board-certified dermatologist can evaluate, recommend treatment

Nail fungus can be distressing for patients, especially during the summer sandal season when feet are exposed.

27 Jul 2017

Self-efficacy has positive effect on physical activity of osteoarthritis patients

Osteoarthritis patients that are more confident in their abilities in the morning go on to be more physically active throughout the day, according to a team of Penn State researchers.

27 Jul 2017

Study examines link between RCT efficacy and real-world effectiveness of cancer therapies

Value in Health, the official journal of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), announced today the publication of new research examining the relationship between the efficacy of randomized controlled trials (RCTs) and real-world effectiveness for oncology treatments.

27 Jul 2017

New study examines efficacy of extended-release guanfacine in children with chronic tic disorders

A new study assessed the safety, tolerability, and effectiveness of extended-release guanfacine in children 6-17 years of age who have chronic tic disorders including Tourette's disorder.

26 Jul 2017

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

A new cooperative research study including Norris Cotton Cancer Center's Lionel Lewis, MB BCh, MD, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with metastatic renal cell cancer (mRCC).

26 Jul 2017

African-American patients have increased gene mutations in tobacco-related tumors, study finds

African-Americans typically have worse outcomes from smoking-related cancers than Caucasians, but the reasons for this remain elusive. However, scientists at Wake Forest Baptist Medical Center have taken a big step toward solving this puzzle.

25 Jul 2017

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

In tumor immunotherapy, the body's own defense system is activated against the tumor cells. However, for the majority of patients, the tumor cells become resistant to the treatments used.

25 Jul 2017

New report identifies lack of knowledge about heart disease in prison populations

The incarcerated population -- both those currently in prison and those who have been released -- are more susceptible to heart disease than the rest of the country's population. And what we know about the factors that play into this is extremely limited, according to researchers.

25 Jul 2017

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Researchers from Genethon, the AFM-Telethon laboratory, Inserm (UMR 1089, Nantes) and the University of London (Royal Holloway) demonstrated the efficacy of an innovative gene therapy in the treatment of Duchenne muscular dystrophy.

25 Jul 2017

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Glioblastoma is a primary brain tumor with dismal survival rates, even after treatment with surgery, chemotherapy, and radiation.

25 Jul 2017

Scientists receive NFL grant to study role of active rehabilitation strategies for concussion management

The NFL will fund a $2.6 million international study on the role of active rehabilitation strategies in concussion management, led by the University of North Carolina at Chapel Hill and the Medical College of Wisconsin.

25 Jul 2017

Researchers present novel gene-editing technique to prevent retinal angiogenesis

A research team from the Schepens Eye Research Institute of Massachusetts Eye and Ear has successfully prevented mice from developing angiogenesis of the retina--the sensory tissue at the back of the eye--using gene-editing techniques with CRISPR-Cas9.

25 Jul 2017

Stem cell centers claim to offer effective heart failure therapy despite lack of FDA approval

Stem cell centers claim to offer effective treatment to patients with heart failure, despite the fact that the treatment is not approved for such use by the U.S. Food and Drug Administration, says the author of research letter in the current issue of JAMA Internal Medicine.

24 Jul 2017

New way of producing flu vaccine could provide better protection against infection

A new way of producing the seasonal flu vaccine could speed up the process and provide better protection against infection.

24 Jul 2017

New trial shows ketamine's effectiveness to treat geriatric depression

Australian researchers have completed the world's first randomised control trial (RCT) assessing the efficacy and safety of ketamine as a treatment for depression in elderly patients.

24 Jul 2017

Critical research strategies and interventions established for pediatric and adolescent HIV

The highest priority research agendas needed to improve the testing and treatment of children and adolescents with HIV were presented at the 9th International Aids Society (IAS) Conference on HIV Science in Paris this weekend.

24 Jul 2017

New survey reveals emotional, practical challenges facing people with idiopathic pulmonary fibrosis

New results from a global survey supported by Boehringer Ingelheim reveal the emotional and practical challenges facing people with idiopathic pulmonary fibrosis (IPF).

24 Jul 2017

Researchers identify issues with current maternal CMV screening methods

Human cytomegalovirus (CMV) is a common virus found worldwide. When CMV infects fetuses, it can cause serious complications such as hearing difficulties and mental retardation in affected infants.

24 Jul 2017

Novel approach could soon play key role in helping veterans overcome PTSD

A novel approach of using visual and physical stimulus to help military veterans address their traumatic experiences could soon play a significant role in helping British veterans overcome post-traumatic stress disorder (PTSD), thanks to a new Cardiff University research project.

24 Jul 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

Efficacy News and Research

Dealing with nail fungus: Board-certified dermatologist can evaluate, recommend treatment

Self-efficacy has positive effect on physical activity of osteoarthritis patients

Study examines link between RCT efficacy and real-world effectiveness of cancer therapies

New study examines efficacy of extended-release guanfacine in children with chronic tic disorders

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

African-American patients have increased gene mutations in tobacco-related tumors, study finds

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

New report identifies lack of knowledge about heart disease in prison populations

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Scientists receive NFL grant to study role of active rehabilitation strategies for concussion management

Researchers present novel gene-editing technique to prevent retinal angiogenesis

Stem cell centers claim to offer effective heart failure therapy despite lack of FDA approval

New way of producing flu vaccine could provide better protection against infection

New trial shows ketamine's effectiveness to treat geriatric depression

Critical research strategies and interventions established for pediatric and adolescent HIV

New survey reveals emotional, practical challenges facing people with idiopathic pulmonary fibrosis

Researchers identify issues with current maternal CMV screening methods

Novel approach could soon play key role in helping veterans overcome PTSD

New genomic research partnership promises to redefine and transform cancer treatment

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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