Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Burkitt lymphoma gene expression signature identified

An international research study involving the University of Nebraska Medical Center, the National Cancer Institute and 10 other institutions has successfully identified the gene expression signature for Burkitt lymphoma.

14 Jun 2006

Circulating bone-marrow derived cells do not contribute to egg formation

Ovulated egg cells, or oocytes, in adult female mice are not formed from germ cells in the blood or bone marrow.

14 Jun 2006

Black women have fewer breast cancers than white women, but their mortality is worse

For decades, researchers have tried to understand why breast cancer in younger black women is such a significant public health problem.

7 Jun 2006

Gene mutation potentially involved in breast cancer initiation

Researchers have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could play a role in the initiation of a major form of breast cancer.

6 Jun 2006

Calpain protein key to preventing or promoting cell death

A protein called calpain can be the key either preventing or promoting the cell death, a Queen's University study has found.

6 Jun 2006

New cervical cancer vaccine offers women 100% protection

Although there have been significant advancements in the screening and treatment of cancer, thousands of women every year contract cervical cancer.

6 Jun 2006

Molecular pathway may contribute to age related diseases

A common molecular denominator in aging and many age-related diseases is oxidative stress.

1 Jun 2006

Organ-recipients' deaths prompt call for suppliers of pet rodents to screen for lymphocytic choriomeningitis virus

A case involving seven transplant recipients killed by a rodent-borne virus that they apparently acquired from donated and infected human organs has prompted a recommendation that regulatory authorities require suppliers of pet rodents to screen their colonies for the virus.

1 Jun 2006

Scientists use "small interfering RNAs" to block the spread of human colorectal cancer cells

Using one of the newest and most powerful tools of biomedical science, University of Texas Medical Branch at Galveston (UTMB) researchers have scored a dramatic success in the battle against colorectal cancer.

1 Jun 2006

Level of selenium-containing proteins in the body instrumental in preventing cancer

Selenium, an essential dietary mineral that can act as an antioxidant when incorporated into proteins, has been shown in many studies to reduce the incidence of cancers -- notably lung, colorectal and prostate.

23 May 2006

First animal model that mimics human head and neck cancer

An Oregon Health & Science University Cancer Institute research laboratory has developed a novel mouse model designed specifically to study the often devastating head and neck squamous cell cancers.

16 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Aggressive cancer treated successfully in mice

White blood cells from a strain of cancer-resistant mice cured advanced cancers in ordinary laboratory mice, researchers at Wake Forest University School of Medicine reported.

9 May 2006

Autopsy study of mild cognitive impairment

A study led by Mayo Clinic demonstrates that mild cognitive impairment, a memory disorder considered a strong early predictor of Alzheimer's disease, not only results in behavioral symptoms, but also structural changes that can be identified in the brain. Findings will be published in the May issue of Archives of Neurology.

9 May 2006

Advancing nanoparticle-based imaging and therapy of brain cancer

Brain cancer is one of the most difficult malignancies to detect and treat, in large part because of the difficulty in getting imaging and therapeutic agents past the so-called blood-brain barrier and into the brain.

9 May 2006

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.

3 May 2006

Epstein reviews recommendations for rebiopsy in patients with high grade pin or atypical foci in prostate biopsy

In the era before extended biopsy schemes, patients with prostate biopsy results showing high grade prostatic intraepithelial neoplasia were recommended for re-biopsy in 3 to 6 months.

2 May 2006

Tumour specific drugs may render therapies based on a tumor's anatomical location obsolete

The results of a new study at Washington University School of Medicine in St. Louis could eventually have oncologists removing their specialties from their shingles by making therapy based on a tumor's anatomical location obsolete.

28 Apr 2006

Friends and family can protect against Alzheimer's disease

Having close friends and staying in contact with family members offers a protective effect against the damaging effects of Alzheimer's disease according to research by physicians at Rush University Medical Center in Chicago. The study, which is currently posted online in The Lancet Neurology, will be published in the May print edition of the journal.

26 Apr 2006

Avian flu vaccine to be developed by Mount Sinai School of Medicine and Bionostra

The Mount Sinai School of Medicine will collaborate with the prestigious Bionostra Group of Spain to develop an avian flu vaccine. The vaccine will protect against the lethal infection of the H5N1 virus.

26 Apr 2006

Pathology News and Research

Further Reading

Burkitt lymphoma gene expression signature identified

Circulating bone-marrow derived cells do not contribute to egg formation

Black women have fewer breast cancers than white women, but their mortality is worse

Gene mutation potentially involved in breast cancer initiation

Calpain protein key to preventing or promoting cell death

New cervical cancer vaccine offers women 100% protection

Molecular pathway may contribute to age related diseases

Organ-recipients' deaths prompt call for suppliers of pet rodents to screen for lymphocytic choriomeningitis virus

Scientists use "small interfering RNAs" to block the spread of human colorectal cancer cells

Level of selenium-containing proteins in the body instrumental in preventing cancer

First animal model that mimics human head and neck cancer

Neurons can produce Alzheimer's-linked apolipoprotein E

Aggressive cancer treated successfully in mice

Autopsy study of mild cognitive impairment

Advancing nanoparticle-based imaging and therapy of brain cancer

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Epstein reviews recommendations for rebiopsy in patients with high grade pin or atypical foci in prostate biopsy

Tumour specific drugs may render therapies based on a tumor's anatomical location obsolete

Friends and family can protect against Alzheimer's disease

Avian flu vaccine to be developed by Mount Sinai School of Medicine and Bionostra

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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