Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Profound alterations in the brain mechanisms that regulate motivated behavior with addiction

Rats that have a strong craving for cocaine have a different biochemical response to the drug than their less-addicted counterparts, researchers at UT Southwestern Medical Center have found.

15 Mar 2006

New AF267B drug reverses key cognitive deficits, pathology in Alzheimer's

A new drug that enhances the activity of a key brain cell receptor involved in Alzheimer's disease (AD) reverses learning and memory deficits in mice engineered to have pathological hallmarks of the disease.

13 Mar 2006

New test for detecting small amounts of proteins in the blood

Researchers at the University of Pennsylvania School of Medicine have developed a paradigm-shifting method for detecting small amounts of proteins in the blood.

13 Mar 2006

Novel device uses light to probe for early signs of cancer

A novel device that could use light to harmlessly and almost instantly probe for early signs of cancer has been developed by researchers at Duke's Pratt School of Engineering.

9 Mar 2006

Dramatic increase in antibiotic-resistant staph infections

Staph infections resistant to antibiotics, previously only associated with hospitalization or prior contact with the healthcare system, are now widespread in the community and coming home.

9 Mar 2006

Genetic switch that turns off an oxygen-poor cell's combustion engine - finding has potential to limit toxic molecules

Johns Hopkins researchers have discovered a previously unrecognized role played by the gene HIF-1 as it helps cell survive when a lack of oxygen decreases production of an energy-rich molecule called ATP and increases production of toxic molecules.

9 Mar 2006

Test for LDH enzyme may help determine risk factors in sickle cell disease

Researchers have found that a simple test for an enzyme called LDH may have significant importance for determining major risk factors in adults with sickle cell disease.

9 Mar 2006

Major biomarker candidates for Alzheimer's disease explored

Alzheimer's disease - specific biomarkers clearly are needed for the differential diagnosis of cognitive impairment in the elderly.

8 Mar 2006

Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Development and evaluation of an open source software tool for deidentification of pathology reports

Researchers have developed new reliable open-source software to remove identifiers from patient reports.

7 Mar 2006

Factor B and H genes found to play role in the development of age-related macular degeneration

A new study, led by researchers at Columbia University Medical Center, pinpoints the role that two genes - Factor H and Factor B - play in the development of nearly three out of four cases of age-related macular degeneration (AMD), a devastating eye disease that affects more than 10 million people in the United States.

7 Mar 2006

Hydrogel scaffold materials used to create stable networks of blood vessels

Yale biomedical engineers have created an implantable system that can form and stabilize a functional network of fine blood vessels critical for supporting tissues in the body, according to a report in the Proceedings of the National Academy of Sciences.

1 Mar 2006

Compound found in marijuana may defend against diabetic retinopathy

A compound found in marijuana won't make you high but it may help keep your eyes healthy if you're a diabetic, researchers say.

1 Mar 2006

Analysis of protein interactions dispels old notions of what's important about them

Discoveries made during the first large-scale analysis of interactions between proteins in our cells hold promise for identifying new genes involved in genetic diseases, according to researchers at Johns Hopkins and the Institute of Bioinformatics (IOB) in Bangalore.

27 Feb 2006

New radiological approach for mass fatality investigation

As far as we know, for the first time in the world a new radiological system was used recently at a mass fatality investigation. A team of researchers led by Professor Guy Rutty of the University of Leicester Forensic Pathology Unit used a mobile MSCT scanner at the mortuary for the examination of the victims of a vehicle mass fatality incident.

27 Feb 2006

Discovery of a new virus in prostate tumors

A team of researchers from Cleveland Clinic and the University of California, San Francisco has discovered a new virus in prostate tumors.

24 Feb 2006

PET and MR imaging reveals white matter degeneration in Huntington's

Using both brain function (PET) and anatomical structure (MR) imaging studies, Italian researchers - within the context of an Italian-British collaboration - discovered that degenerative and dysfunctional events occur in individuals many years before the onset of Huntington's disease - particularly in the brain's white matter - an area not previously considered primarily involved with the disease.

24 Feb 2006

Genetic variations help predict risk for salt-induced high blood pressure

Researchers led by UVa Health System pathologist Robin Felder, Ph.D., have demonstrated that looking for several variations of genes that control blood pressure can predict the risk for high blood pressure caused by high levels of salt.

23 Feb 2006

Discovery of molecule that may hold key to learning and memory

Independent research teams from Harvard Medical School and Children's Hospital Boston have identified a master protein that sheds light on one of neurobiology's biggest mysteries--how neurons change as a result of individual experiences.

23 Feb 2006

New device to boost supply and quality of blood platelets

Cancer and open-heart surgery patients, disaster victims, organ or bone marrow transplant recipients, and others who require life-saving blood platelet transfusions will benefit from equipment invented by a researcher at the University of British Columbia's Centre for Blood Research (CBR).

21 Feb 2006