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Study finds new cancer driver which is fast, furious and loud

The Fast and the Furious movie franchise meets the Fast N' Loud television series to define an oncogene that drives 35% of prostate cancers.

27 Jun 2019

Researchers use genetically manipulated virus to combat prostate cancer

Researchers at the São Paulo State Cancer Institute in Brazil have succeeded in using a genetically manipulated virus to destroy tumor cells upon injection into mice with prostate cancer.

27 Jun 2019

Study provides new insight into development of asthma

Researchers at Karolinska Institutet in Sweden have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways.

27 Jun 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Cascade aggravates hereditary storage diseases

In rare, hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing.

26 Jun 2019

New prostate cancer test could bring an end to unnecessary biopsies

Researchers have developed a new urine test to diagnose aggressive forms of prostate cancer, which could mean an end to the unnecessary treatment of men with non-aggressive cancers.

26 Jun 2019

Zebrafish offers new clues to regenerating damaged cardiac tissue

Research into the hearts of zebrafish, a pet shop staple marked by their eponymous stripes, has shed light on ways the human heart muscle could be healed following damage.

26 Jun 2019

Patients with biliary tract cancer have altered genetic architecture in immune system

Patients with biliary tract cancer have altered genetic architecture in some immune system receptors.

26 Jun 2019

Children with birth defects have elevated cancer risk, study reveals

Childhood cancer is a rare occurrence in the overall population but may be somewhat more frequent in children born with birth defects.

26 Jun 2019

New model could help find new cancer drugs, speed up traffic, combat disease

A new mathematical model of the structure of networks could help find new cancer drugs, speed up traffic flow and combat sexually transmitted disease.

26 Jun 2019

High prevalence of multiresistant intestinal bacteria in Vietnamese hospitals

Around half of patients admitted to hospital in Vietnam are carriers of multiresistant intestinal bacteria, which are resistant to carbapenems, a group of broad-spectrum antibiotics.

26 Jun 2019

Coffee may boost weight loss, concludes study

Coffee has been shown to increase the release of heat from brown fat, potentially boosting weight loss efforts.

25 Jun 2019

Scientists investigate genomic pillars behind transition from healthy hearts to heart failure

Scientists investigating heart failure have been limited to studying diseased heart tissue in the lab -- understandably, as people don't tend to pluck out a healthy heart for the sake of research.

25 Jun 2019

Researchers identify missing link between amyloid plaques and tau tangles in Alzheimer's

Years before symptoms of Alzheimer's disease appear, two kinds of damaging proteins silently collect in the brain: amyloid beta and tau. Clumps of amyloid accumulate first, but tau is particularly noxious.

25 Jun 2019

Researchers generate huge amounts of genome-data from many ruminant species

The project gives valuable new insights on how genetic adjustments through evolution have rendered the ruminants one of the most successful groups of animals on the planet

25 Jun 2019

Immature mood neurons develop during adolescence

Researchers have discovered a mysterious group of neurons in the amygdala -- a key center for emotional processing in the brain -- that stay in an immature, prenatal developmental state throughout childhood.

24 Jun 2019

Researchers develop new technique to image cell populations and genetic contents

Researchers have come up with a new way to image cell populations and their genetic contents. Their study, appearing June 20 in the journal Cell, describes how a technique called DNA microscopy helps illuminate the spatial organization of genetic material within cells and tissues without specialized, expensive optical equipment.

24 Jun 2019