Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

The discovery of a gene, called PRDM1, as a tumor suppressor sheds new light on the cause - and possible treatment - of diffuse large B-cell lymphomas (DLBCLs), a cancer of the blood's B-lymphocytes. DLBCLs comprise about 30 percent of non-Hodgkin's lymphomas.

25 Apr 2006

Rare abdominal cancer diagnosis being looked at in a different manner

Their experience treating a rare type of abdominal cancer has helped physicians at Wake Forest University Baptist Medical Center make a new discovery that may change the way it is diagnosed.

24 Apr 2006

New finding provides researchers with renewable source for macrophages and neutrophils

A new approach to generating large quantities of two types of white blood cells that are critical for destroying invading bacteria, viruses and other pathogens in humans has been developed by researchers at the University of California, San Diego (UCSD) School of Medicine.

19 Apr 2006

First gene therapy human trial in the United States for a form of muscular dystrophy under way

The clinical trial for Duchenne muscular dystrophy (DMD) tests the safety and effectiveness of a therapy that was developed over two decades by scientists at the University of North Carolina Chapel Hill's School of Medicine and the University of Pittsburgh.

16 Apr 2006

First evidence that circulating endothelial microparticles lead to heart valve disease

Under normal physiological conditions, low levels of microparticles are continually being shed into the blood from the endothelium - the cells that line the inside of blood vessels and some organs -and appear to cause no problems.

13 Apr 2006

Environmental change and viral mutations combine to fuel outbreaks of a deadly mosquito-borne disease

Environmental change and viral mutations have combined to fuel outbreaks of a deadly mosquito-borne disease that have plagued South and Central America for the last 100 years, a new study by University of Texas Medical Branch at Galveston (UTMB) and Colorado State University researchers reports.

11 Apr 2006

Research explains why recipients of growth hormone therapy may develop colon polyps

The use of growth hormone therapy has been linked in some people to the development of colon polyps, a possible precursor to colorectal cancer - but medical researchers have debated the extent of a cancer risk.

11 Apr 2006

Losartan can prevent progression of Marfan syndrome

A commonly prescribed blood pressure medication may provide the first ray of hope in preventing potentially deadly complications of Marfan syndrome, a genetic disease that weakens the structural meshwork of blood vessels.

11 Apr 2006

Fat cells surrounding coronary arteries may play a role in development of heart disease

The fat cells that surround coronary arteries may play a central and previously unrecognized role in development of cardiovascular disease, according to a study by University of Iowa researchers.

11 Apr 2006

Protein loss linked to colon polyp risk from growth hormone

10 Apr 2006

Inflammation cuts both ways

Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder.

6 Apr 2006

Protein in urine may point to more sensitive screening tests for women with ovarian cancer

According to the National Cancer Institute, ovarian cancer causes more deaths than any other cancer of the female reproductive system. An estimated 20,180 new cases of ovarian cancer are expected in the United States this year.

4 Apr 2006

Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep

While newly published research confirms that under laboratory circumstances prion-protein can be absorbed across the gut, it also shows that this is unlikely to occur in real life.

4 Apr 2006

New biomarkers could help detect ovarian cancer much earlier

The search for a specific protein that could help diagnose ovarian cancer in its early stages has for years eluded researchers who are seeking a reliable and accurate test for the disease.

4 Apr 2006

Omega-3 fatty acids inhibit the growth of liver cancer cells

Two new studies by a University of Pittsburgh research team suggest that omega-3 fatty acids - substances that are found in high concentrations in fish oils and certain seeds and nuts - significantly inhibit the growth of liver cancer cells.

3 Apr 2006

St. Jude develop relatively simple and inexpensive test for acute lymphoblastic leukemia

Investigators at St. Jude Children's Research Hospital have developed a relatively simple and inexpensive test that identifies children with acute lymphoblastic leukemia (ALL) who have responded well enough to their first round of chemotherapy that they might be successfully treated with a much less aggressive follow-up treatment.

3 Apr 2006

New evidence questions the simple link between prion proteins and vCJD

While newly published research confirms that under laboratory circumstances prion-protein can be absorbed across the gut, it also shows that this is unlikely to occur in real life.

30 Mar 2006

Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas

Inactivation of a "tumor suppressor" gene could be a major cause of a class of blood cancers called diffuse large B-cell lymphomas, reports a team of researchers at the Weill Medical College of Cornell University.

30 Mar 2006

Study on fruit flies offers new approach to understand human response to viral infections

A research team led by UC Riverside scientists has shown that the common fruit fly can serve as an excellent model for studying the immunity animals are born with for fighting viral infections.

28 Mar 2006

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have discovered how a protein called Pmel17 is sorted by pigment cells in the skin and eye to make a fiber matrix that eventually sequesters melanin, the dark pigment found in skin, hair, and eyes.

28 Mar 2006

Pathology News and Research

Further Reading

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

Rare abdominal cancer diagnosis being looked at in a different manner

New finding provides researchers with renewable source for macrophages and neutrophils

First gene therapy human trial in the United States for a form of muscular dystrophy under way

First evidence that circulating endothelial microparticles lead to heart valve disease

Environmental change and viral mutations combine to fuel outbreaks of a deadly mosquito-borne disease

Research explains why recipients of growth hormone therapy may develop colon polyps

Losartan can prevent progression of Marfan syndrome

Fat cells surrounding coronary arteries may play a role in development of heart disease

Protein loss linked to colon polyp risk from growth hormone

Inflammation cuts both ways

Protein in urine may point to more sensitive screening tests for women with ovarian cancer

Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep

New biomarkers could help detect ovarian cancer much earlier

Omega-3 fatty acids inhibit the growth of liver cancer cells

St. Jude develop relatively simple and inexpensive test for acute lymphoblastic leukemia

New evidence questions the simple link between prion proteins and vCJD

Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas

Study on fruit flies offers new approach to understand human response to viral infections

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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