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Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Researchers exploring the developing central nervous system of fruit flies have identified nonelectrical cells that transition the brain from highly plastic into a less moldable, mature state.

8 Apr 2021

Rice bioengineer wins NIH support for a new strategy to fight cystic fibrosis

Chemical and biomolecular engineer Xue Sherry Gao of Rice University's Brown School of Engineering has won National Institutes of Health support for a new strategy to fight cystic fibrosis.

8 Apr 2021

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds.

8 Apr 2021

New tool helps measure communication development in youth with Down syndrome

Expressive language sampling (ELS) is a useful tool for measuring communication development in youth with Down syndrome, a new multi-site study has found.

8 Apr 2021

IRB Barcelona researchers find the Achilles heel of some lung tumors

In cancer, personalized medicine takes advantage of the unique genetic changes in an individual tumor to find its vulnerabilities and fight it.

8 Apr 2021

USC Stem Cell scientist receives $2.56 million NIH grant to explore 'synthetic' embryonic development

Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment.

8 Apr 2021

Study finds more children infected by coronavirus during the second wave in Germany

A study by Helmholtz Zentrum München concludes that during the second Corona wave, three to four times more children in Bavaria, Germany were infected with the Corona virus than reported via PCR tests.

8 Apr 2021

Microrna-29 molecule controls brain maturation in mammals

A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions.

8 Apr 2021

PNA-based gene editing technique can advance gene discovery

In an article published in the April 8 issue of Nature, the National Institutes of Health's Somatic Cell Gene Editing Consortium provided a detailed update on the progress of their nationwide effort to develop safer and more effective methods to edit the genomes of disease-relevant somatic cells and reduce the burden of disease caused by genetic changes.

8 Apr 2021

Cross-border asthma study investigates hygiene hypothesis amid COVID-19 pandemic

A cross-border investigation of children's susceptibility to asthma and other childhood illnesses in the United States and Mexico is the focus of a new study led by researchers in the Asthma and Airway Disease Research Center at the University of Arizona Health Sciences.

8 Apr 2021

Evidence of monoclonal antibodies effectively neutralizing SARS-CoV-2 variants

Makdasi et al. The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against novel viral variants. bioRxiv, 2021. doi: https://doi.org/10.1101/2021.04.01.438035, https://www.biorxiv.org/content/10.1101/2021.04.01.438035v2

7 Apr 2021

Phase II of Singapore's National Precision Medicine strategy to begin in April 2021

Precision medicine is part of Singapore's Research, Innovation and Enterprise (RIE) 2025 strategic goal to transform and protect the health of every Singaporean.

7 Apr 2021

Urolithin A shows promise to slow progression of Duchenne Muscle Dystrophy

Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today.

7 Apr 2021

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines.

7 Apr 2021

Study offers localized treatment direction for a cause of Crohn's disease

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects.

7 Apr 2021

Manual workers are twice as likely to develop ALS, study finds

ALS is a progressive neurological disease that attacks the nerves that interact with the body's muscles. The disease typically leads to complete paralysis of the body, robbing patients of their ability to walk, speak, eat and breathe.

7 Apr 2021

Mouse model provides new understanding about Folling Disease

In Norway, all newborn children are tested for 25 rare genetic diseases through the Newborn Screening program, and the most common of these is phenylketonuria (abbreviated to PKU), known as Folling Disease.

7 Apr 2021

New test for Lyme disease can reliably distinguish between early- and late-stage patients

For those who live in an area blighted by ticks, the threat of Lyme disease can cast a shadow over the joy of spring and summer.

7 Apr 2021

Finding ways to reverse a genetic cause of poor stress responses in mice

Everyone faces stress occasionally, whether in school, at work, or during a global pandemic. However, some cannot cope as well as others.

7 Apr 2021

Researchers characterize genetic intra-tumor heterogeneity across cancer genomes

Researchers at the Francis Crick Institute, as part of an international collaboration of scientists through the Pan-Cancer Analysis of Whole Genomes Consortium, have analyzed the whole genomes of tumor samples from over 2,600 patients with different types of cancer.

7 Apr 2021

Genetic News and Research

Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Rice bioengineer wins NIH support for a new strategy to fight cystic fibrosis

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

New tool helps measure communication development in youth with Down syndrome

IRB Barcelona researchers find the Achilles heel of some lung tumors

USC Stem Cell scientist receives $2.56 million NIH grant to explore 'synthetic' embryonic development

Study finds more children infected by coronavirus during the second wave in Germany

Microrna-29 molecule controls brain maturation in mammals

PNA-based gene editing technique can advance gene discovery

Cross-border asthma study investigates hygiene hypothesis amid COVID-19 pandemic

Evidence of monoclonal antibodies effectively neutralizing SARS-CoV-2 variants

Phase II of Singapore's National Precision Medicine strategy to begin in April 2021

Urolithin A shows promise to slow progression of Duchenne Muscle Dystrophy

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

Study offers localized treatment direction for a cause of Crohn's disease

Manual workers are twice as likely to develop ALS, study finds

Mouse model provides new understanding about Folling Disease

New test for Lyme disease can reliably distinguish between early- and late-stage patients

Finding ways to reverse a genetic cause of poor stress responses in mice

Researchers characterize genetic intra-tumor heterogeneity across cancer genomes

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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