Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Aromatase inhibitors may slow growth of lung cancer

A few years ago researchers discovered that, much like breast tumors, some lung tumors also thrive on estrogen. Now a medical student conducting research on a Howard Hughes Medical Institute (HHMI) fellowship and colleagues have managed to stop the growth of human lung cancer cells in mice with a class of breast cancer drugs called aromatase inhibitors.

15 Dec 2005

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

Transport mechanisms for serotonin

Researchers at The Forsyth Institute have discovered that the transport mechanisms for serotonin - the chemical substance involved in transmitting signals between neurons, and which has a role in anxiety and mood disorders - play a key role in determining where organs are positioned in the body during embryonic development.

7 Dec 2005

New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005

Breast CT may be better than mammography at detecting breast lesions

Breast CT, an investigational technology for early breast cancer detection, may be better than mammography at detecting breast lesions and is much more comfortable for women, researchers from the University of California, Davis reported at the annual meeting of the Radiological Society of North America in Chicago.

2 Dec 2005

Cellular and molecular mechanisms that accelerate the development and progression of atherosclerosis

A McMaster University study on atherosclerosis will be featured on the cover of the December issue of the high impact American Heart Association scientific journal, Arteriosclerosis, Thrombosis and Vascular Biology.

2 Dec 2005

Protein target for Parkinson's disease

Researchers at Johns Hopkins' Institute for Cell Engineering (ICE) have discovered a protein that could be the best new target in the fight against Parkinson's disease since the brain-damaging condition was first tied to loss of the brain chemical dopamine.

2 Dec 2005

Pancreatic cancer and ecoendoscopy

Cancer of the pancreas is the number five in the list of deaths due to cancers in Spain and the third causing deaths due to digestive tumour.

28 Nov 2005

Completion of the genetic sequencing of the 1918 influenza A virus

An article by Robert Belshe, M.D., of Saint Louis University School of Medicine in the New England Journal of Medicine reviews recent "spectacular achievements of contemporary molecular biology" that hold great importance as the world prepares for a possible flu pandemic.

28 Nov 2005

Potential new treatment for pancreatic cancer

Johns Hopkins Kimmel Cancer Center researchers are encouraged by early results of a treatment vaccine for pancreatic cancer, a disease with few options and low odds for long-term survival.

28 Nov 2005

Study finds AKT blocks cancer cell motility

PIn investigating the molecular mechanisms of cancer cell motility - the unique property that enables cancer to spread from its primary origin to other parts of the body - researchers have uncovered a surprising role for the AKT/PKB (protein kinase B) enzyme

26 Nov 2005

Accurate and rapid method of diagnosing bacterial meningitis

Several hundred serious cases of bacterial meningitis are diagnosed in Australians every year. Bacterial meningitis is a medical emergency that requires immediate diagnosis and treatment, however doctors have always faced difficulty in diagnosis, both in children and adults.

21 Nov 2005

Study reveals how T cells analyze and react to the signals of infection at the immunological synapse

The immune system is highly complex. The cast of characters alone required to marshal an immune response to a foreign invader can number in the millions as the body's soldiers, T cells, are called into action.

20 Nov 2005

Trichostatin A may fight lupus and atherosclerosis simultaneously

People with lupus are prone to premature accelerated atherosclerosis. Now scientists at Wake Forest University School of Medicine think they have a way to prevent or decrease this atherosclerosis and prevent heart attacks.

16 Nov 2005

Researchers can now identify patients likely to respond to cancer drug therapy

Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent.

13 Nov 2005

Flu expert calls for mandatory vaccination of health care workers

Johns Hopkins' senior hospital epidemiologist and flu expert is calling for mandatory vaccination of all health care workers as the best means of protecting patients and hospital staff from widespread outbreaks of the viral illness.

10 Nov 2005

Introgen's INGN 241 combined with Celebrex kills breast cancer cells

Introgen Therapeutics, Inc. today reported the publication of preclinical data demonstrating that INGN 241 works synergistically with celecoxib (Celebrex) marketed by Pfizer to inhibit the growth and increase apoptosis (cell death) of breast cancer cells.

8 Nov 2005