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High-resolution DNA sequencing data for 37,000 children and parents released

The first resource containing high-resolution DNA sequencing data for over 37,000 children and parents collected over multiple decades from across the UK is now available to researchers worldwide.

4 Mar 2025

New Arab Pangenome Reference promises advancements in precision medicine

Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine, a publication in Nature Medicine reveals.

4 Mar 2025

Oropouche virus goes global: Study exposes new risks from viral reassortment

Scientists trace the rapid spread of Oropouche virus beyond the Amazon, revealing its evolution through reassortment and the critical role of human mobility in its transmission.

4 Mar 2025

New tool revolutionizes primer design for infectious disease detection

Researchers from the Zhang Liye Laboratory have developed a groundbreaking tool that revolutionizes the way researchers design primers for detecting pathogens.

4 Mar 2025

Researchers uncover genetic basis of aggressive prostate cancer

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

3 Mar 2025

Groundbreaking studies reveal how DNA folding guides sperm cell development

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell.

3 Mar 2025

Pioneering the world’s first CRISPR medicine for sickle cell disease

When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes.

3 Mar 2025

Scientists uncover how herpes virus fuels Alzheimer’s disease

Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.

2 Mar 2025

St. Jude scientists discover how retinoic acid selectively kills metastatic neuroblastoma cells

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10-15%.

2 Mar 2025

NIH decision to cap indirect costs sparks concern in scientific community

On February 7, 2025, the U.S. National Institutes of Health announced a decision to cap indirect cost reimbursement-which supports the critical infrastructure and staff that make biomedical research possible-at 15%.

28 Feb 2025

Lactylation in the heart reveals key insights into cardiac regeneration

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

28 Feb 2025

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the cholesterol drug fenofibrate (Triglide, Fibricor, Lipofen) as an investigational and potential treatment for patients with HPV+ cervical and HPV+ head and neck cancer (HNSCC).

28 Feb 2025

Atlantia Clinical Trials: Investigating the interrelation of microbiology and immunology

Atlantia Clinical Trials investigates the role of microbiomes in immunity, focusing on gut and lung interactions to develop innovative health solutions.

From Atlantia Clinical Trials 28 Feb 2025

New deep-learning framework improves spatial transcriptomics analysis

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning.

27 Feb 2025

Global partnerships transforming diagnosis and treatment for rare genetic diseases

Global partnerships that embed scientific research into clinical care are revolutionising the diagnosis and treatments for children with rare genetic diseases, according to a new report.

27 Feb 2025

New AI tool enhances discovery of genes involved in neurodevelopmental conditions

Researchers have developed an artificial intelligence (AI) approach that accelerates the identification of genes that contribute to neurodevelopmental conditions such as autism spectrum disorder, epilepsy and developmental delay.

26 Feb 2025

Tardigrade protein offers radiation protection for cancer patients

About 60 percent of all cancer patients in the United States receive radiation therapy as part of their treatment.

26 Feb 2025

Can coffee push back Parkinson’s? New study uncovers key genetic link

Higher coffee consumption is causally linked to delayed onset of Parkinson’s disease but does not affect disease risk or progression, according to a Mendelian randomization study.

25 Feb 2025

Discovery of new bat flu strain with potential to infect other species

Scientists have identified a novel influenza A virus (H18N12) in fishing bats in the Colombian Caribbean, revealing genetic reassortment events that impact viral adaptability and host transmission.

25 Feb 2025

Mass General Brigham study uncovers 16 novel Alzheimer's risk genes

Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer's disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer's disease in underrepresented groups.

25 Feb 2025