Immune System News and Research

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Study shows mRNA-based COVID vaccines enhance effectiveness of immune checkpoint therapy

Patients with cancer who received mRNA-based COVID vaccines within 100 days of starting immune checkpoint therapy were twice as likely to be alive three years after beginning treatment, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

21 Oct 2025

Stressful life factors early in life may triple the risk of developing psoriasis later

New longitudinal research reveals that severe stress caused by changes in family structure like divorce or separation experienced during the first year of life may triple the risk of developing psoriasis later in life.

21 Oct 2025

Leveraging the microbiome to promote healthy living and aging

From probiotic pills to skincare products to dedicated meal plans, the microbiome is all the rage in the health and wellness space.

21 Oct 2025

Scientists uncover a key mechanism that protects the skin from harmful inflammation

Researchers at VIB and Ghent University have uncovered a key mechanism that protects the skin from harmful inflammation.

21 Oct 2025

Blood proteins reveal MS immune system attack starts years before symptoms

By the time patients start seeking care for multiple sclerosis (MS), the disease has already been damaging their brains for years. But until recently, scientists didn't understand which brain cells were being targeted or when the injury began.

21 Oct 2025

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

A new cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) shows that a drug that utilizes the body's immune system to target and eliminate cancer cells appeared to reduce the risk of distant metastases for an aggressive form of skin cancer when given immediately after surgery, but did not significantly reduce the overall risk of recurrence, which was a co-primary endpoint of the trial.

21 Oct 2025

Food allergy diagnoses plummet after guideline implementation

Peanuts represent one of the most common causes of immunoglobulin E (IgE)-mediated, or anaphylactic, food allergies in children, yet a landmark study found that early introduction of peanut to infants may lower their risk of developing this allergy.

21 Oct 2025

Nanoplastics with environmental coatings can sneak past the skin's defenses

Plastic is ubiquitous in the modern world, and it's notorious for taking a long time to completely break down in the environment - if it ever does.

17 Oct 2025

Research reveals how immune cells orchestrate the release of toxic granules

When immune cells strike, precision is everything. New research reveals how natural killer and T cells orchestrate the release of toxic granules – microscopic packages that destroy virus-infected or cancerous cells.

17 Oct 2025

New insights into how bacteria can drive treatment resistance in oral and colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center have discovered a previously unknown mechanism that explains how bacteria can drive treatment resistance in patients with oral and colorectal cancer.

16 Oct 2025

UIC researchers discover an important cellular mechanism that drives aging

As our hairs go gray and our muscles weaken with age, our immune system also changes. In particular, the stem cells that become blood or immune cells can develop mutations, potentially leading to cancers or other dysfunctions.

16 Oct 2025

Thymic health found to predict immunotherapy success in cancer patients

The health of the thymus - a key part of the body's immune system - is associated with cancer patients' outcomes to immune checkpoint inhibitor treatment, according to a ground-breaking international study reported at ESMO 2025.

16 Oct 2025

Researchers uncover TRAT1's central role in T helper cell function

Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the immune system: the protein molecule TRAT1 (T Cell Receptor Associated Transmembrane Adaptor 1) plays a central role in how so-called T helper cells (a specialised subgroup of immune cells) distinguish between attack and self-control - an important mechanism for restraining inflammation and preventing autoimmune diseases. The findings have recently been published in the journal Cell Communication and Signaling.

16 Oct 2025

FDA shares safety guidance for people considering microneedling

Being pricked by tiny needles may sound like a strange way to make your skin look better, but that's the concept behind a skin care technique called microneedling.

16 Oct 2025

Low-dose steroids show promise for treating severe kidney inflammation

Will it be possible to treat severe kidney inflammation with fewer drugs in the future? A new study by the University Hospital Bonn (UKB), the University of Bonn, and the University of Hamburg gives cause for hope.

15 Oct 2025

Experimental gene therapy restores immune system function in children with genetic immune disorder

An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder.

15 Oct 2025

Gene therapy shows long-term success in children with rare immune disorder

Results from the largest cohort of children who received a gene therapy for a rare immunodeficiency condition have shown the long-term safety and efficacy of the curative treatment, in a study led by a UCL researcher.

15 Oct 2025

Immune checkpoint inhibitor TIGIT found to promote tissue healing

Immune checkpoint inhibitors are well known as a form of cancer treatment. Researchers at UZH have now identified a new, important function of these inhibitors: promotion of tissue healing.

15 Oct 2025

Combination therapy shows promising results in patients with rare subtype of non-Hodgkin lymphoma

Combining an epigenetic therapy with an anti-PD-1 antibody, which uses the body's natural response to viral infections, showed promising results in patients with relapsed or refractory natural killer/T-cell lymphoma (R/R NKTL), a rare and aggressive cancer with limited treatment options.

15 Oct 2025

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Immune System News and Research

Study shows mRNA-based COVID vaccines enhance effectiveness of immune checkpoint therapy

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

Stressful life factors early in life may triple the risk of developing psoriasis later

Leveraging the microbiome to promote healthy living and aging

Scientists uncover a key mechanism that protects the skin from harmful inflammation

Blood proteins reveal MS immune system attack starts years before symptoms

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

Food allergy diagnoses plummet after guideline implementation

Nanoplastics with environmental coatings can sneak past the skin's defenses

Research reveals how immune cells orchestrate the release of toxic granules

New insights into how bacteria can drive treatment resistance in oral and colorectal cancer

UIC researchers discover an important cellular mechanism that drives aging

Thymic health found to predict immunotherapy success in cancer patients

Researchers uncover TRAT1's central role in T helper cell function

FDA shares safety guidance for people considering microneedling

Low-dose steroids show promise for treating severe kidney inflammation

Experimental gene therapy restores immune system function in children with genetic immune disorder

Gene therapy shows long-term success in children with rare immune disorder

Immune checkpoint inhibitor TIGIT found to promote tissue healing

Combination therapy shows promising results in patients with rare subtype of non-Hodgkin lymphoma

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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