Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Estimating COVID-19 case prevalence in New York City

Researchers estimated the prevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in New York City (NYC).

2 May 2022

Neutralizing antibodies produced following COVID-19 BNT162b2 vaccine found to activate complement cascade

Researchers investigated the complement component 1q (C1q) binding and subsequent complement activation by neutralizing antibodies (nAbs) produced following COVID-19 vaccination.

2 May 2022

SARS-CoV-2 viral shedding varies widely in asymptomatic and mildly ill patients

In a recent study published in the Nature Microbiology journal, researchers assessed the longitudinal viral dynamics in asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

1 May 2022

Poor asthma control triggered by SARS-CoV-2

In a new study, researchers noted that COVID-19 could trigger poor pediatric asthma control.

29 Apr 2022

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Researchers surveilled coronaviruses found in bats via targeted genomic sequencing.

29 Apr 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Findings of the HITCH randomized clinical trial show lack of improvement in COVID-19 on temporary androgen suppression

Researchers investigated whether temporary androgen suppression by degarelix improved the clinical outcomes among male patients hospitalized with COVID-19.

27 Apr 2022

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

The current study deals with the results of serum cytokine analysis in a small group of pregnant women with and without COVID-19 in the third trimester in a single New York City hospital.

27 Apr 2022

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Researchers revealed that native FokI relaxation might be induced, resulting in FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids.

27 Apr 2022

Asymptomatic SARS-CoV-2 infection among research personnel: Study

A recent research paper published in the journal Public Library of Science (PLOS) ONE analyzed asymptomatic coronavirus disease 2019 (COVID-19) in personnel engaged in academic study.

26 Apr 2022

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Researchers developed a highly pathogenic mouse-adapted SARS-CoV-2 strain to model mild, moderate, or COVID-19.

26 Apr 2022

Study explores SARS-CoV-2 antibody responses in mild COVID-19 cases

In a new study, researchers evaluated antibody responses in mild cases of coronavirus disease 2019.

26 Apr 2022

COVID-19 vaccine can elicit a distinct T cell-dominant immune-mediated hepatitis

In a recent study published in the Journal of Hepatology, researchers reported that the coronavirus disease 2019 (COVID-19) vaccination could elicit a distinct T cell-dominant immune-mediated hepatitis.

25 Apr 2022

Researchers develop new platform capable of mitochondrial DNA editing

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED.

25 Apr 2022

Treating COVID-19 using monoclonal antibodies during pregnancy

Researchers assessed the efficiency efficacy and safety of monoclonal antibodies for treating SARS-CoV-2 during pregnancy.

25 Apr 2022

Vaccine effectiveness against COVID-19 infection and related hospitalization

Researchers assessed the effectiveness of COVID-19 vaccines against COVID-19 infections and related hospitalizations.

25 Apr 2022

Within-host model for the description of SARS-CoV-2 viral dynamics in the upper respiratory tract

A team of UK-based scientists has recently developed a within-host model to determine the dynamics of SARS-CoV-2 infection in the upper respiratory tract of affected individuals.

25 Apr 2022

The challenges of Omicron

A new review published in sums up the position of Omicron as a potential threat to human health, especially in the context of controlling this pandemic.

25 Apr 2022

Monoclonal-antibody combination AZD7442 prevents COVID-19

In a recent study published in The New England Journal of Medicine, the researchers examined the monoclonal-antibody combination AZD7442 to prevent coronavirus disease 2019 (COVID-19).

25 Apr 2022

Polymerase Chain Reaction News and Research

Further Reading

Estimating COVID-19 case prevalence in New York City

Neutralizing antibodies produced following COVID-19 BNT162b2 vaccine found to activate complement cascade

SARS-CoV-2 viral shedding varies widely in asymptomatic and mildly ill patients

Poor asthma control triggered by SARS-CoV-2

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Artificial circular RNAs found to bypass cellular antiviral responses

Findings of the HITCH randomized clinical trial show lack of improvement in COVID-19 on temporary androgen suppression

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Asymptomatic SARS-CoV-2 infection among research personnel: Study

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Study explores SARS-CoV-2 antibody responses in mild COVID-19 cases

COVID-19 vaccine can elicit a distinct T cell-dominant immune-mediated hepatitis

Researchers develop new platform capable of mitochondrial DNA editing

Treating COVID-19 using monoclonal antibodies during pregnancy

Vaccine effectiveness against COVID-19 infection and related hospitalization

Within-host model for the description of SARS-CoV-2 viral dynamics in the upper respiratory tract

The challenges of Omicron

Monoclonal-antibody combination AZD7442 prevents COVID-19

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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