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Discovery of T cell exhaustion offers new pathway to more powerful immunotherapies

St. Jude Children's Research Hospital immunologists have discovered how immune cells called T cells become "exhausted" -- unable to do their jobs of attacking invaders such as cancer cells or viruses.

28 Jun 2017

Hospitals ramp up hyperbaric therapy for diabetics, despite concerns

The Villages Regional Hospital did not sweat its decision to add hyperbaric oxygen therapy in 2013.

28 Jun 2017

Apomorphine infusion found to be effective treatment for Parkinson’s patients with motor fluctuations

Apomorphine subcutaneous infusion is an effective treatment for Parkinson patients whose motor fluctuations are poorly controlled by conventional therapies.

28 Jun 2017

Paxman supports launch of global initiative to develop best practices in scalp cooling

Led by six globally-recognized experts in cancer care, the organization known as CHILL, Cancer-related Hair Loss, International Leadership and Linkage, announced today an initiative to collect and track evidence-based patient information and clinical guidance.

From Paxman 28 Jun 2017

Western University neuroscientist launches world's largest sleep-and-cognition study

Renowned Western University neuroscientist Adrian Owen has launched the world's largest sleep-and-cognition study to help researchers learn the effects on our brains of sleep and sleep deprivation.

27 Jun 2017

Insomnia drug appears to have opposite effect for patients with neurologic conditions

In a new systematic review in JAMA Neurology, Michigan Medicine researchers found reason to further explore the surprising effects of zolpidem that have been observed outside the scope of its primary Food and Drug Administration approval.

27 Jun 2017

Study: Physical activity plus Fitbit intervention can help depressed women during early alcohol recovery

The first three months of sobriety pose the greatest risk for relapse, and the greatest challenge for intervention efforts.

27 Jun 2017

Drug cocktail may be effective in preventing progressive organ dysfunction, deaths from sepsis

Sepsis presents a major challenge for health care providers, especially in low-income countries where the mortality rate can exceed 60 percent.

27 Jun 2017

New monoclonal antibody shows efficacy in chronic migraine patients with medication overuse

A new human antibody may soon become available as a specific medication for preventing frequent migraine attacks.

27 Jun 2017

Self-help intervention may be useful as initial treatment to manage symptoms of chronic fatigue syndrome

A self-help approach to a graded exercise program, supervised by a specialist physiotherapist, is safe and may reduce fatigue for some people with chronic fatigue syndrome (CFS), according to a new trial of 200 people published in The Lancet.

24 Jun 2017

Cognitive decline may be prevented using interventions but may be inadequate says report

New research shows that there are several interventions that could help prevent cognitive decline. According to the latest report entitled “Preventing Cognitive Decline and Dementia: A Way Forward,” from the National Academies of Sciences, Engineering, and Medicine (NASEM), cognitive training, increase in physical activity, control of blood pressure adequately among those with a high blood pressure are all fruitful measures to reduce cognitive decline. However evidence to support these three interventions is encouraging but insufficient to justify a public health campaign focused on their adoption.

22 Jun 2017

Promoting innate detoxification mechanisms could be efficient strategy to reduce cellular oxidative stress

Promoting innate detoxification mechanisms in the body and discovering which supplements increase the efficacy of those biochemical pathways could be an efficient strategy to reduce the cellular oxidative stress and protect our health, according to an article published in the journal Food Chemistry, by the researchers Rafael Franco, from the Institute of Biomedicine of the University of Barcelona, and Eva Martínez Pinilla, from the Institute of Neurosciences of Asturias and the University of Oviedo.

21 Jun 2017

Researchers highlight need for paradigm shift in management of type 2 diabetes

Heart disease is a leading cause of death worldwide and exacerbated by type 2 diabetes, yet diabetes treatment regimens tend to focus primarily on blood sugar maintenance.

21 Jun 2017

Animal model of Gulf War illness hints at possible ways to mitigate symptoms

When hundreds of thousands of American troops deployed to the Persian Gulf in 1990 and 1991 in what is now called the First Gulf War, they were exposed to a variety of chemicals.

20 Jun 2017

Study: DBS shows promise for treating patients with post-stroke pain syndrome

Deep brain stimulation (DBS) of the ventral striatum/anterior limb of the internal capsule is safe and feasible in addressing the affective component of pain in patients with post-stroke pain syndrome.

20 Jun 2017

Study shows insecticide-resistance monitoring as key to controlling mosquitoes that spread Zika

One of the most common insecticides used in the battle against the Aedes aegypti mosquito has no measurable impact when applied in communities where the mosquito has built up resistance to it, a study led by Emory University finds.

20 Jun 2017

First-ever clinical study for effective treatment of mycetoma begins in Sudan

The first-ever double-blind, randomized clinical trial for an effective treatment for the severely neglected disease mycetoma has enrolled its first patient at the Mycetoma Research Centre in Khartoum, Sudan.

19 Jun 2017

Yoga may be helpful in treating chronic low back pain

Physical therapy has been recommended as part of treatment for low back pain for a very long time. Low back pain affects millions worldwide and may be short lasting or chronic or longer in duration for some individuals. Long term or intermittently occurring low back pain is referred as chronic low back pain.

19 Jun 2017

IsoNTech to showcase latest advances in safer, alternative nicotine products

The First International Symposium on Nicotine Technology takes place today in Warsaw, Poland. The symposium looks at new and emerging technologies in the area of nicotine delivery and will be showcasing the latest advances in alternative nicotine delivery systems, next generation devices, and the science behind them.

19 Jun 2017

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Domainex Ltd. expands its partnership with Imperial College London, to discover novel therapies that reduce heart muscle damage during heart attacks. The aim is to discover a drug that inhibits the enzyme MAP4K4, which plays a key role in triggering cell death following a heart attack.

19 Jun 2017

Efficacy News and Research

Discovery of T cell exhaustion offers new pathway to more powerful immunotherapies

Hospitals ramp up hyperbaric therapy for diabetics, despite concerns

Apomorphine infusion found to be effective treatment for Parkinson’s patients with motor fluctuations

Paxman supports launch of global initiative to develop best practices in scalp cooling

Western University neuroscientist launches world's largest sleep-and-cognition study

Insomnia drug appears to have opposite effect for patients with neurologic conditions

Study: Physical activity plus Fitbit intervention can help depressed women during early alcohol recovery

Drug cocktail may be effective in preventing progressive organ dysfunction, deaths from sepsis

New monoclonal antibody shows efficacy in chronic migraine patients with medication overuse

Self-help intervention may be useful as initial treatment to manage symptoms of chronic fatigue syndrome

Cognitive decline may be prevented using interventions but may be inadequate says report

Promoting innate detoxification mechanisms could be efficient strategy to reduce cellular oxidative stress

Researchers highlight need for paradigm shift in management of type 2 diabetes

Animal model of Gulf War illness hints at possible ways to mitigate symptoms

Study: DBS shows promise for treating patients with post-stroke pain syndrome

Study shows insecticide-resistance monitoring as key to controlling mosquitoes that spread Zika

First-ever clinical study for effective treatment of mycetoma begins in Sudan

Yoga may be helpful in treating chronic low back pain

IsoNTech to showcase latest advances in safer, alternative nicotine products

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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