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Study reveals sex-differences in aging of the brain stem cell niche

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis.

7 Apr 2021

Scientists develop new method that advances single-cell transcriptomic technologies

Scientists at Oxford Brookes University have developed a new single-cell transcriptomic method which will aid multiple fields of biology, including the study of human health, disease and injury.

7 Apr 2021

Individuals with Major Depressive Disorder have accelerated cellular aging

Cells from individuals with Major Depressive Disorder (MDD) were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a study by a multidisciplinary team of UC San Francisco scientists, in collaboration with others.

7 Apr 2021

Study shows how leptin suppresses appetite

Since the discovery of leptin in the 1990s, researchers have wondered, how does leptin, a hormone made by body fat, suppress appetite? Despite tremendous gains in the intervening three decades, many questions still remain.

7 Apr 2021

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others.

7 Apr 2021

Study shows stronger link between Down syndrome and acute myeloid leukemia

A new large-scale study led by UC Davis Health and UC San Francisco researchers assessed the risks of leukemia in children with Down syndrome.

7 Apr 2021

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions.

7 Apr 2021

Tissue architecture impacts the evolutionary course of cancer

Tumors are genetically diverse with different mutations arising at different times throughout growth and development.

6 Apr 2021

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre have discovered how certain proteins ensure the repair of errors introduced into the DNA during its replication.

6 Apr 2021

Chemical substances in some cosmetic and beauty products could increase risk of endometriosis

Researchers from the University of Granada and the "San Cecilio de Granada" Teaching Hospital confirm that endocrine disruptors—chemical substances that may mimic or block the action of hormones—are present in some cosmetic products

6 Apr 2021

Study discovers how microcephaly and blindness may develop in Zika-infected fetuses

A study led by Edward Wojcik, PhD, Associate Professor of Biochemistry & Molecular Biology at LSU Health New Orleans School of Medicine, identified how microcephaly (abnormally small heads) and blindness may develop in Zika-infected fetuses, as well as a new way to potentially prevent these neurodevelopmental defects.

6 Apr 2021

UCI receives $4.2 million grant to study sporadic inclusion body myositis affecting aging adults

The National Institute of Arthritis and Musculoskeletal and Skin Diseases has awarded UCI a 5-year, $4.2 million grant to study sporadic inclusion body myositis (sIBM), which affects aging adults causing asymmetric muscle weakness and severe disability. The disease is currently untreatable and poorly understood.

6 Apr 2021

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

The rarity of spinal muscular atrophy (SMA) means that promising new treatments may be tested in only a limited spectrum of patients before approval. Investigators evaluated a newly approved drug, onasemnogene abeparvovec, in a broader spectrum of patients in order to obtain expanded data on its side effects profile.

6 Apr 2021

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Scientists recently explored the transmission dynamics of currently circulating variants of SARS-CoV-2 in a southern African country. By analyzing the genomic sequences of these variants, they have identified a novel SARS-CoV-2 variant with multiple spike mutations. They have temporarily designated the variant A.VOI.V2.

6 Apr 2021

Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

To date, little evidence has been documented regarding the immune responses after the onset of the symptoms or virus detection. Further, no cross-sectional studies have been conducted that define the time of infection. Thereby, no report is available that explains the relationship between the earliest immune responses to COVID-19 and temporal kinetics. New research deals with this research gap using blood transcriptomics, multiparameter flow cytometry, and T cell receptor (TCR) sequencing methods.

6 Apr 2021

What Covid means for the athlete’s heart

For sports fans across the country, the resumption of the regular sports calendar has signaled another step toward post-pandemic normality. But for the athletes participating in professional, collegiate, high school or even recreational sports, significant unanswered questions remain about the aftereffects of a Covid infection.

6 Apr 2021

Genetic News and Research

Study reveals sex-differences in aging of the brain stem cell niche

Scientists develop new method that advances single-cell transcriptomic technologies

Individuals with Major Depressive Disorder have accelerated cellular aging

Study shows how leptin suppresses appetite

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Study shows stronger link between Down syndrome and acute myeloid leukemia

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

Tissue architecture impacts the evolutionary course of cancer

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Chemical substances in some cosmetic and beauty products could increase risk of endometriosis

Study discovers how microcephaly and blindness may develop in Zika-infected fetuses

UCI receives $4.2 million grant to study sporadic inclusion body myositis affecting aging adults

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

What Covid means for the athlete’s heart

Researchers take key step toward new drugs and vaccines to combat COVID-19

Researchers define genetic landscape of uterine leiomyosarcomas

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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