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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Unique antibody responses after third COVID-19 mRNA vaccination

Researchers observed that a third messenger ribonucleic acid COVID-19 vaccine elicits a unique antibody response.

16 May 2022

Study suggests the seasonal H1N1 flu virus may be a direct descendant of the 1918 influenza strain that caused a global flu pandemic

A new study published in Nature Communications implemented recent advances in nucleic acid recovery to sequence one complete and two partial 1918 influenza virus genomes from specimens sampled in Berlin and Munich.

16 May 2022

Immunotherapy combined with chemoradiation and surgery could help treat nonmetastatic gastroesophageal cancer

Immunotherapy has transformed treatment for patients with stage 4 metastatic esophageal and gastric cancers. In patients with these malignancies, immunotherapy has been shown to prolong survival when patients' tumors exhibit a high expression of an immune-related protein called PD-L1.

16 May 2022

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Researchers compared the immunogenicity of or and reactogenicity to the BNT162b2 vaccine in Japanese adults and elders.

16 May 2022

Super-antibody UT28K shows broad-spectrum activity against SARS-CoV-2 variants

A study, published online in the journal mAbs, describes a novel mAb, UT28K, that has promising broadly neutralizing activity against the SARS-CoV-2 virus.

15 May 2022

CDC study reveals hybrid SARS-CoV-2 spike from Delta/Omicron recombination event

The US Centers for Disease Control and Prevention (CDC) has conducted national-level genomic surveillance to identify and characterize delta-omicron recombinant genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A total of nine genomes with a hybrid delta-omicron spike protein have been identified.

14 May 2022

Novel approach allows islet transplants to survive and control diabetes

In type 1 diabetes, an autoimmune response attacks the pancreas's insulin-producing beta cells, leading to marked fluctuations in blood sugar levels. Lifelong daily insulin treatments are standard for patients, but replacing lost beta cells through transplants of islets, a group of cells in the pancreas, represents an attractive option.

13 May 2022

Artificial proteins as specific and versatile neutralizing binders targeting the spike of SARS-CoV-2

Researchers demonstrated that the biosynthetic proteins called αReps addressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein could be novel SARS-CoV-2 antivirals

13 May 2022

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Islet cell transplants are a promising treatment that can cure difficult-to-treat type 1 diabetes. The cells, taken from a donor pancreas, provide patients with a sustainable and tightly controlled source of insulin.

13 May 2022

New discovery has potential to stop inflammation at the "growing end"

Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances.

13 May 2022

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Study explores macromolecular viral entry inhibitors as broad-spectrum first-line antivirals with anti-SARS-CoV-2 activities

Researchers created polystyrene sulfonate with significantly different molar masses, constructed these polymers as an exterior around spherical gold nanoparticles of various sizes to improve multivalency effects, measured antiviral effects of the antivirals on numerous viruses in vitro, and investigated the method of interaction of the leads with SARS-CoV-2 and lentiviral particles.

13 May 2022

Researchers discover new gene that confers resistance to prostate cancer treatment

Northwestern Medicine investigators have identified a gene that confers resistance to a common prostate cancer treatment, according to a study published in Cancer Research.

13 May 2022

Researchers identify compounds from Aspergillus that may be effective against SARS-CoV-2

Researchers from Ain Shams University have been exploring the use of compounds isolated from Aspergillus sp. against SARS-CoV-2.

13 May 2022

Investigating effectiveness of mRNA booster against SARS-CoV-2 Omicron in individuals primed with mRNA or inactivated virus vaccines

Scientists have determined the effectiveness of different vaccination regimens in eliciting humoral immune responses against the SARS-CoV-2 Omicron variant.

13 May 2022

Study reveals serum proteomic signatures of long COVID patients

In a recent study posted to the bioRxiv*preprint server, researchers evaluated the serum proteomic signatures of long coronavirus disease (COVID) patients.

13 May 2022

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

In a recent study posted to the bioRxiv* preprint server, researchers explored the role of the N-terminal domain (NTD) of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein in SARS-CoV-2 fusion with the host membranes and coronavirus disease 2019 (COVID-19).

12 May 2022

Protein News and Research

Further Reading

Unique antibody responses after third COVID-19 mRNA vaccination

Study suggests the seasonal H1N1 flu virus may be a direct descendant of the 1918 influenza strain that caused a global flu pandemic

Immunotherapy combined with chemoradiation and surgery could help treat nonmetastatic gastroesophageal cancer

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Super-antibody UT28K shows broad-spectrum activity against SARS-CoV-2 variants

CDC study reveals hybrid SARS-CoV-2 spike from Delta/Omicron recombination event

Novel approach allows islet transplants to survive and control diabetes

Artificial proteins as specific and versatile neutralizing binders targeting the spike of SARS-CoV-2

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

New discovery has potential to stop inflammation at the "growing end"

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Study explores macromolecular viral entry inhibitors as broad-spectrum first-line antivirals with anti-SARS-CoV-2 activities

Researchers discover new gene that confers resistance to prostate cancer treatment

Researchers identify compounds from Aspergillus that may be effective against SARS-CoV-2

Investigating effectiveness of mRNA booster against SARS-CoV-2 Omicron in individuals primed with mRNA or inactivated virus vaccines

Study reveals serum proteomic signatures of long COVID patients

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

Bayesian viral allele selection for SARS-CoV-2 genomic surveillance

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

Cost-effective ovine antibody-based therapy against SARS-CoV-2 infection

Editorial Focus eBook - Proteomics eBook

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