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Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Loyola researchers have identified a tumor gene that may help to predict survival outcomes in patients with cancer of the mouth and tongue.

5 May 2016

Detailed digital models of human organs could bring substantial benefits to clinical trials

Computer simulations of disease processes and detailed digital models of our organs could provide more accurate monitoring and outcome measurements for clinical trials, according to research being presented in Sheffield today.

5 May 2016

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

Winner of the Best International Abstract Award, Hadie Adams, presented his research, Characterizing the Temporal Evolution of ICP and Cerebrovascular Reactivity after Severe Traumatic Brain Injury, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers from the Scientific Research Institute of Physical-Chemical Medicine, MIPT, the company M&S Decisions and the research department of Yandex have built a computer model of the interaction between different bacteria, and between bacteria and the gut wall.

5 May 2016

Research provides new insight into cellular composition of IDH1-mutant gliomas

Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Limiting blue-light exposure could increase quality, length of sleep

Building on existing evidence, vision researchers have found that limiting exposure to blue light after sunset increases the quality and length of sleep. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Seattle, Wash.

5 May 2016

Alcohol drinking problem makes people less satisfied with life

Research suggests people are momentarily happier when drinking alcohol -- but that over longer periods, drinking more does not make them more satisfied with life.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

OGT launches Cytocell FISH probes for glial tumours

Oxford Gene Technology (OGT), The Molecular Genetics Company, has launched its CE-IVD labelled Cytocell Aquarius® 1p36/1q25 and 19q13/19p13 Deletion Probe Kit*, a cost-effective fluorescence in situ hybridisation (FISH) kit for the reliable investigation of glial tumours.

4 May 2016

Anaesthesia services given seal of approval by Royal College

The quality of anaesthesia services at Sheffield Teaching Hospitals has been recognised with accreditation from the Royal College of Anaesthetists.

4 May 2016

University hospital in Finland invests in digital pathology from Sectra

Kuopio University Hospital will be Finland's first fully digital pathology department following its investment in Sectra's IT solution for efficient storage, review and sharing of digital pathology images. The Diagnostic Imaging Center at Kuopio University Hospital is thereby extending its existing solution for handling radiology images (PACS) to also include pathology images. This enables in-depth cooperation between the hospital's radiologists and pathologists; two of the key functions in effective clinical care.

4 May 2016

Finding treatments for rare diseases: an interview with Dr Richard Thompson

It is estimated that around 400 rare diseases have licenced treatments, and a large proportion of these are a consequence of orphan drug legislation, which has helped to incentivise the production of drugs for small patient populations.

4 May 2016

Candida yeast infections more common in men with schizophrenia or bipolar disorder

In a study prompted in part by suggestions from people with mental illness, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of men with schizophrenia or bipolar disorder than in those without these disorders, and that women with schizophrenia or bipolar disorder who tested positive for Candida performed worse on a standard memory test than women with schizophrenia or bipolar disorder who had no evidence of past infection.

4 May 2016

Innovative noise reduction technology SEDA helps tackle babble signals from cochlear implants

Wearers of cochlear implants and hearing aids often have difficulty teasing out what someone is saying over "babble" -- the cacophony of other talkers -- and other ambient sounds. New York University researchers have devised a novel solution: an algorithmic approach that, like making drinkable water from pond water, distills the talker's voice from a turbid wash of noise.

4 May 2016

Study analyzes PI, RI of patients who underwent AVM embolization and surgical resection

Winner of the Louise Eisenhardt Traveling Scholarship, Sophia F. Shakur, MD, IFAANS, presented her research, Changes in Pulsatility and Resistance Indices of Cerebral Arteriovenous Malformation Feeder Arteries after Embolization and Surgery, during the 2016 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.

4 May 2016

BMJ experts reveal medical error as third main cause of death in the U.S

Medical error is the third leading cause of death in the US after heart disease and cancer, say experts in The BMJ today.

4 May 2016

Muscle & Nerve study links intramuscular fat with BMI and physical activity levels

Ultrasound-estimated percent intramuscular fat of muscles in the lower extremity was inversely associated with physical activity level and positively associated with body mass index in a recent study.

4 May 2016

Researchers investigate incidence of new position-related nerve deficit in spine surgery

Winner of the Sanford J. Larson, MD, PhD, Award, Gurpreet Surinder Gandhoke, MD, presented his research, Incidence of Position Related Neuropraxia in 4,489 Consecutive Patients Undergoing Spine Surgery. Role of SSEP Monitoring? during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

4 May 2016

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Although there have been discussions about chronic obstructive pulmonary disease (COPD), a condition impacting 24 million Americans, and depression, there has been little research showing the impact depression has on patients with COPD. Two studies published in the April issue of the journal CHEST found one in four patients with COPD suffer from depressive symptoms, and if not treated, those symptoms can have a negative effect on their overall health and treatment effectiveness.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

Research News and Research

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Detailed digital models of human organs could bring substantial benefits to clinical trials

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Research provides new insight into cellular composition of IDH1-mutant gliomas

Limiting blue-light exposure could increase quality, length of sleep

Alcohol drinking problem makes people less satisfied with life

Bayer-new phase 3 liver cancer data

OGT launches Cytocell FISH probes for glial tumours

Anaesthesia services given seal of approval by Royal College

University hospital in Finland invests in digital pathology from Sectra

Finding treatments for rare diseases: an interview with Dr Richard Thompson

Candida yeast infections more common in men with schizophrenia or bipolar disorder

Innovative noise reduction technology SEDA helps tackle babble signals from cochlear implants

Study analyzes PI, RI of patients who underwent AVM embolization and surgical resection

BMJ experts reveal medical error as third main cause of death in the U.S

Muscle & Nerve study links intramuscular fat with BMI and physical activity levels

Researchers investigate incidence of new position-related nerve deficit in spine surgery

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

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