Clinical Trial News and Research

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Bowel cancer patients with high levels of vitamin D are more likely to survive the disease

Bowel cancer patients with high levels of vitamin D in their blood are more likely to survive the disease, a study shows.

9 Jul 2014

Antibiotic treatment for patients who underwent gall bladder removal does not reduce infection risk

Among patients who underwent gall bladder removal for acute calculous cholecystitis, lack of postoperative antibiotic treatment did not result in a greater incidence of infections, according to a study in the July 9 issue of JAMA.

9 Jul 2014

UCLA project receives $15M to restore lost memory functions in brain-injured people

The UCLA Program in Memory Restoration has been awarded up to $15 million by the Defense Advanced Research Projects Agency (DARPA) for a four -year project aiming to help brain-injured people restore lost memory functions.

9 Jul 2014

Children who received home visits from nurses are less likely to die from preventable causes

Low-income mothers and their first-born children who received home visits from nurses were less likely to die from preventable causes during a two-decade period studied by a University of Colorado School of Medicine professor, according to a report published in JAMA Pediatrics - a leading, peer-reviewed journal of the American Medical Association.

8 Jul 2014

Study: Behavioral weight loss can help manage menopausal hot flashes

Now women have yet one more incentive to lose weight as a new study has shown evidence that behavioral weight loss can help manage menopausal hot flashes.

8 Jul 2014

New test for TB could improve speed and accuracy of diagnosis for deadliest diseases

A new test for tuberculosis (TB) could dramatically improve the speed and accuracy of diagnosis for one of the world's deadliest diseases, enabling health care providers to report results to patients within minutes, according to a study published this week in the journal Angewandte Chemie.

8 Jul 2014

$FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL$

FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL

Novartis announced today that the United States Food and Drug Administration has granted Breakthrough Therapy status to CTL019, an investigational chimeric antigen receptor (CAR) therapy for the treatment of pediatric and adult patients with relapsed/refractory acute lymphoblastic leukemia (r/r ALL).

7 Jul 2014

Grunenthal Group submits Marketing Authorization Application to EMA for ZALVISO

AcelRx Pharmaceuticals, Inc. and Grunenthal Group announced today that Grunenthal has submitted a Marketing Authorization Application (MAA) to the European Medicines Authority for ZALVISO for the management of moderate to severe acute pain in adult patients in a medically supervised environment.

7 Jul 2014

Poor nutrition, health cause disparities in fetal growth and newborn size worldwide

Babies' growth in the womb and their size at birth, especially their length, are strikingly similar the world over - when babies are born to healthy, well-educated and well-nourished mothers.

7 Jul 2014

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

Jeffrey Tyner, Ph.D., assistant professor of Cell, Developmental & Cancer Biology for Oregon Health & Science University (OHSU) and a researcher with OHSU's Knight Cancer Institute, has won a distinguished award from the American Association for the Advancement of Science (AAAS) for the development of a research program that more rapidly identifies the mutations driving a patient's cancer and accelerates development of precision treatments.

4 Jul 2014

Multicenter trial aims to find safety, effectiveness of probiotics in infants with stomach flu

Consumers worldwide spend billions of dollars each year on probiotic foods and supplements. But studies evaluating probiotics - microorganisms believed to aid digestive health - have been limited.

4 Jul 2014

Scientists produce drug compound with potential to block HIV transmission in women

Scientists at the University of Nebraska-Lincoln College of Engineering's Biological Process Development Facility have successfully produced a drug compound with potential to block HIV transmission in women.

4 Jul 2014

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

UCB, a global biopharmaceutical leader, and Dermira, Inc., a privately held US-based dermatology company, announced today that they have entered into an exclusive licensing agreement for the development and future commercialization of Cimzia (certolizumab pegol) in dermatology.

3 Jul 2014

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

Researchers at the Cleveland Clinic Lou Ruvo Center for Brain Health have conducted the first-ever analysis of clinical trials for Alzheimer's disease (AD), revealing an urgent need to increase the number of agents entering the AD drug development pipeline and progressing successfully towards new therapy treatments.

3 Jul 2014

Combination of cognitive behavioral therapy and medication reduces relapse in depressed youths

Cognitive behavioral therapy in addition to medication improves the long-term success of treatment for children and adolescents suffering from depression, a new UT Southwestern Medical Center study indicates.

3 Jul 2014

Testosterone therapy does not increase men's risk for heart attack, shows UTMB study

Testosterone prescriptions for older men in the United States have increased more than three-fold over the past decade. Recent studies linking testosterone use with increased risk of heart attack and stroke have caused widespread concern among patients and their families.

2 Jul 2014

Study explores neurological outcomes in patients treated for traumatic brain injury

In patients with a traumatic brain injury (TBI), neither the administration of the hormone erythropoietin (EPO) or maintaining a higher hemoglobin concentration through blood transfusion resulted in improved neurological outcome at 6 months, according to a study in the July 2 issue of JAMA.

2 Jul 2014

New gene therapy for Acute Intermittent Porphyria

Angeles suffers from a severe and rare genetic disease called Acute Intermittent Porphyria (AIP). This means, one of her genes restrains her liver to produce a specific protein needed for the metabolism of the blood. During an AIP attack Angeles usually feels intense abdominal pain, and her mental status changes. Women live at an increased risk to trigger the symptoms, because porphyria is related to the menstrual cycle.

2 Jul 2014

New smartphone-based system detects changes in patients' behavioral patterns

Mental illness accounts for 90 percent of all reported suicides and places the largest burden of any disease on social and economic infrastructures worldwide, according to the World Health Organization.

1 Jul 2014

Prophage autologous cancer vaccine extends survival in patients with newly diagnosed GBM

Agenus Inc., announced final results from a single-arm, multi-institutional, open-label, Phase 2 study showing that patients with newly diagnosed glioblastoma multiforme (GBM) who received Agenus' Prophage autologous cancer vaccine added to the standard of care treatment, lived nearly twice as long as expected.

1 Jul 2014

Clinical Trial News and Research

Bowel cancer patients with high levels of vitamin D are more likely to survive the disease

Antibiotic treatment for patients who underwent gall bladder removal does not reduce infection risk

UCLA project receives $15M to restore lost memory functions in brain-injured people

Children who received home visits from nurses are less likely to die from preventable causes

Study: Behavioral weight loss can help manage menopausal hot flashes

New test for TB could improve speed and accuracy of diagnosis for deadliest diseases

FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL

Grunenthal Group submits Marketing Authorization Application to EMA for ZALVISO

Poor nutrition, health cause disparities in fetal growth and newborn size worldwide

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

Multicenter trial aims to find safety, effectiveness of probiotics in infants with stomach flu

Scientists produce drug compound with potential to block HIV transmission in women

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

Combination of cognitive behavioral therapy and medication reduces relapse in depressed youths

Testosterone therapy does not increase men's risk for heart attack, shows UTMB study

Study explores neurological outcomes in patients treated for traumatic brain injury

New gene therapy for Acute Intermittent Porphyria

New smartphone-based system detects changes in patients' behavioral patterns

Prophage autologous cancer vaccine extends survival in patients with newly diagnosed GBM

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