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Specific gene may play a causal role in heart disease independent of cholesterol levels

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

1 Apr 2021

Study reveals reason behind high risk of leukemia in children with Down syndrome

Children with Down syndrome are 20-times more likely to develop acute lymphocytic leukemia (ALL) and 150-times more likely to develop acute myeloid leukemia (AML) compared to their typical peers.

31 Mar 2021

Study reports on two cats that caught COVID-19

Our feline friends are also vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to new research posted to the preprint server bioRxiv. The researchers diagnosed two cats living in France with mild symptomatic COVID-19 illness. The virus was most likely transmitted from their owners.

31 Mar 2021

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Clinicians using a new viral screening test can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses--like influenza--that might be mistaken for the coronavirus.

31 Mar 2021

Gene therapy restores vison in dogs with severe form of Leber congenital amaurosis

Gustavo Aguirre and William Beltran, veterinary ophthalmologists and vision scientists at the University of Pennsylvania School of Veterinary Medicine, have studied a wide range of different retinal blinding disorders.

31 Mar 2021

B.1.1.7 rapidly becoming the dominant SARS-CoV-2 variant in the United States

The faster-spreading B.1.1.7 variant of SARS-CoV-2 first detected in the United Kingdom, the coronavirus that causes COVID-19, is quickly on its way to becoming the dominant variant of the virus in the United States, according to a study from scientists at Scripps Research and the COVID-19 test maker Helix.

31 Mar 2021

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

The ongoing COVID-19 pandemic, caused by SARS-CoV-2, is now established to be more likely to lead to symptomatic and serious illness in males relative to females. This may extend as far back as pregnancy, suggests a recent study.

31 Mar 2021

Scientists discover new genetic disease that causes abnormal brain development in children

Scientists have discovered a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development and often early onset cataracts.

31 Mar 2021

Scientists receive NIH grant to monitor COVID-19 in wastewater

Everyone poops, and now scientists are using this bodily function to develop a detailed analysis of the virus that causes COVID-19, known as SARS-CoV-2.

31 Mar 2021

Comparing the transmission routes of two SARS-CoV-2 variants of concern

The research team had previously identified the UK variant as having higher viral RNA shedding than the D614G variant. However here, they wanted to compare the transmission of such variants through different routes of potential infection: direct contact, aerosol (airborne droplets), and fomite (objects which may be contaminated and therefore spread infectious agents).

30 Mar 2021

Prime editing enables more precise correction of genetic problems than traditional CRISPR

The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say.

30 Mar 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

New machine learning technique reveals mutational signatures in cancer patients

Researchers at the Johns Hopkins Kimmel Cancer Center used machine learning techniques to detect mutational signatures in cancer patients.

30 Mar 2021

Researchers examine the evolutionary race between SARS-CoV-2 and human defenses

Researchers have analyzed this evolution of the virus based on evolutionary ecology theory. Using the virus genomes available in the Global Initiative on Sharing Avian Influenza Data (GISAID) database, the researchers focused their inquiry on mutations in the receptor-binding domain (RBD) on the spike protein of SARS-CoV-2.

30 Mar 2021

Imported COVID-19 cases responsible for spread of the UK and Brazil SARS-CoV-2 variants in Italy

A new study examines a major consequence of the second wave of COVID-19 infection—namely, the rapid emergence of new viral lineages and variants.

30 Mar 2021

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

A new study describes the kinetics of the antibody response to the earliest approved vaccines against COVID-19, which were developed on an mRNA platform.

30 Mar 2021

Researchers develop broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine

In the continued need for next-generation vaccines that confer broad protection against COVID-19, scientists developed an adjuvanted SARS-CoV-2 Spike Ferritin Nanoparticle (SpFN) vaccine.

30 Mar 2021

New molecular pathway helps steer moving cells in specific directions

Working with fruit flies, scientists at Johns Hopkins Medicine say they have identified a new molecular pathway that helps steer moving cells in specific directions.

30 Mar 2021

New system facilitates real-time imaging of biological, pathological processes

Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, have developed a novel far-red light-emitting luciferin-luciferase system that is more efficient than those available commercially. An article on the subject is published in the International Journal of Molecular Sciences.

30 Mar 2021

New diagnostic test can detect COVID-19 virus even when it mutates

A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has developed a diagnostic test that can detect the virus that causes COVID-19 even after it has gone through mutations.

30 Mar 2021

Genetic News and Research

Specific gene may play a causal role in heart disease independent of cholesterol levels

Study reveals reason behind high risk of leukemia in children with Down syndrome

Study reports on two cats that caught COVID-19

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Gene therapy restores vison in dogs with severe form of Leber congenital amaurosis

B.1.1.7 rapidly becoming the dominant SARS-CoV-2 variant in the United States

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

Scientists discover new genetic disease that causes abnormal brain development in children

Scientists receive NIH grant to monitor COVID-19 in wastewater

Comparing the transmission routes of two SARS-CoV-2 variants of concern

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

New machine learning technique reveals mutational signatures in cancer patients

Researchers examine the evolutionary race between SARS-CoV-2 and human defenses

Imported COVID-19 cases responsible for spread of the UK and Brazil SARS-CoV-2 variants in Italy

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

Researchers develop broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine

New molecular pathway helps steer moving cells in specific directions

New system facilitates real-time imaging of biological, pathological processes

New diagnostic test can detect COVID-19 virus even when it mutates

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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