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World's largest research initiative to mutate all mouse genes

The world's largest research initiative to mutate all mouse genes is now able to reach the summit because the ambitious EUCOMMTOOLS project started on October 1, 2010. This project is being coordinated by Helmholtz Zentrum München and will finalize the groundwork for the analysis of all mouse gene functions. The findings will contribute to a better understanding of the pathogenesis of widespread diseases such as Alzheimer's, depression, diabetes, chronic lung diseases or cancer.

28 Oct 2010

Researchers unveil evolution in pancreatic tumours

In new research published today, researchers uncover evolution in action in cancer cells. They show the forces of evolution in pancreatic tumours mean that not only is cancer genetically different between different patients, but each new focus of cancer spread within a patient has acquired distinct mutations.

28 Oct 2010

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Today in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.

28 Oct 2010

New computational techniques to overcome obstacles in hard-to-study genes

Scientists have invented methods to scout the human genome's repetitive landscapes, where DNA sequences are highly identical and heavily duplicated. These advances, as reported today in Science, can identify subtle but important differences among people in the number and content of repeated DNA segments.

28 Oct 2010

deCODE genetics publishes high resolution recombination map of human genome in Nature journal

Scientists from deCODE genetics today publish in Nature the highest resolution recombination map of the human genome yet developed. Recombination is the reshuffling of the genome that occurs in the formation of eggs and sperm: we inherit one version of each chromosome from each of our parents, and create novel blends of the two that we pass on to our offspring.

28 Oct 2010

BioNanomatrix nanoAnalyzer 1000 System to be introduced at ASHG Annual Meeting

BioNanomatrix, Inc., which is developing and commercializing breakthrough single-molecule genomic analysis technology, will introduce next month the nanoAnalyzer 1000 System at the American Society of Human Genetics (ASHG) Annual Meeting from November 2-6, 2010 in Washington, D.C.

28 Oct 2010

Study: lncRNA are involved in host response to viral infection

Scientists have demonstrated for the first time that a certain class of RNA (known as long non-protein-coding RNA [lncRNA]) are involved in the host response to viral infection. These findings, published today in the online journal mBio-, could greatly change the way scientists look at the body's response to viral infection.

27 Oct 2010

Addition of ECC probe to SOLiD System's chemistry achieves greater than 99.99% single-read accuracy

Life Technologies Corporation a provider of innovative life science solutions, today announced that it has established a new standard in accuracy for next generation sequencing. By adding an Exact Call Chemistry (ECC) proprietary probe to its market leading ligation chemistry, the company has demonstrated greater than 99.99% average single-read accuracy.

27 Oct 2010

Illumina announces single flow cell version of HiSeq 2000 sequencing system

Illumina, Inc. today announced HiSeq 1000, a single flow cell version of the company's HiSeq 2000 sequencing system. HiSeq 1000 is designed for researchers who want the ease of use, industry-leading cost per gigabase (Gb) and data rate of the HiSeq 2000 but do not currently require its throughput. As their research scales, users will be able to upgrade their system to the HiSeq 2000 and double their output.

From Illumina, Inc. 27 Oct 2010

Long non-protein coding RNAs respond to SARS virus infection, says study

For the first time, scientists have discovered that a poorly understood class of RNA produced in a mammal's cells during a respiratory virus attack may affect the outcome of the infection. Their findings are reported today in mBio, a journal of the American Society for Microbiology.

27 Oct 2010

Illumina 2010 third quarter revenue increases 50% to $237.3 million

Illumina, Inc. today announced its financial results for the third quarter of 2010.

From Illumina, Inc. 27 Oct 2010

SNP array's snapshot of Anopheles gambiae genome can help eliminate malaria

The development and first use of a high-density SNP array for the malaria vector mosquito have established 400,000 genetic markers capable of revealing new insights into how the insect adapts to outsmart insecticides and other preventive measures, according to findings published in the current edition of the journal Science.

26 Oct 2010

Maven Semantic updates Lymphocyte Cell Biology research database

Maven Semantic announces updates to their Lymphocyte Cell Biology research database. The new database is now available to marketing, business development, competitor intelligence, KOL, medical affairs and related departments in the life sciences sector.

26 Oct 2010

Helicos names Illumina and Life Technologies as additional defendants in lawsuit against Pacific Biosciences

Helicos BioSciences Corporation announced today that it has amended its lawsuit against Pacific Biosciences of California, Inc. for patent infringement by naming Illumina, Inc. and Life Technologies Corporation as additional defendants.

From Illumina, Inc. 25 Oct 2010

CARTaGENE database meets 20k participant milestone

This week, the last questionnaire was filled out and the final vial of blood was drawn, closing CARTaGENE's first ambitious goal of collecting samples and data from 20 000 Quebecers.

25 Oct 2010

UC San Diego researchers receive two federal grants for biomedical informatics

Researchers at the University of California, San Diego School of Medicine, led by Lucila Ohno-Machado, MD, PhD, chief of the Division of Biomedical Informatics in the Department of Medicine, have received two federal grants totaling more than $25 million to develop new ways to gather, analyze, use and share vast, ever-increasing amounts of biomedical information.

25 Oct 2010

Cellectis and CiRA commence iPS cell scientific collaboration

Cellectis, the French genome engineering specialist, and the Center for iPS Cells Research and Application (CiRA) of Kyoto University, Kyoto, Japan, have announced today that they have started a scientific collaboration to combine Cellectis' genome engineering technologies with CiRA's induced pluripotent stem cell (iPS) technology to improve the natural characteristics of iPS cells for use as cellular tools.

25 Oct 2010

Shrink announces agreement to produce high content screening tool for biotech R&D subsidiary

Shrink Nanotechnologies, Inc. an innovative nanotechnology company developing products and licensing opportunities in the alternative energy industry, medical diagnostics and sensors and biotechnology research and development tools businesses, announced today that it has entered into an agreement to produce a high content screening tool for its biotech R&D subsidiary, Shrink Chips LLC.

25 Oct 2010

Researchers find evidence that A. gambiae mosquito is evolving into two strains, could present challenges for malaria control efforts

The Anopheles gambiae mosquito, one of the major carriers of the malaria parasite in Sub-Saharan Africa, is evolving in two directions, according to two studies published Thursday in the journal Science, Scientific American's Observations blog reports.

25 Oct 2010

Scientists use Affymetrix custom microarray to advance malarial study

Affymetrix, Inc. announced today that an international team of researchers led by scientists at Boston College, the Broad Institute, and Imperial College London used an Affymetrix custom microarray to advance the study of malaria by assessing the variation in genetic structure and detecting known and novel genetic differences among malaria vector mosquito populations.

25 Oct 2010