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Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, has successfully delivered the second preclinical candidate compound (PCC) in its collaboration with Fosun Pharma in June 2024, a potential innovative therapeutic using synthetic lethal strategy for the treatment of solid tumors.

5 Jul 2024

Why do aortic aneurysms form in specific locations?

The sites where vascular aneurysms typically form have a predilection from the outset, even in healthy people. This is shown by a study conducted by medical researchers from Bochum and Bonn.

5 Jul 2024

DNA repair mutations act as a switch for bowel cancer

Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at UCL and University Medical Center Utrecht.

5 Jul 2024

Regulatory and psychological considerations of CGM use in people not living with diabetes

A new narrative review led by researchers at UCL and Birmingham Children's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD).

5 Jul 2024

Baby boys more likely to achieve HIV cure or remission after in-utero infection

Baby girls are more likely to acquire HIV from their mothers during pregnancy or childbirth than infant boys, who are conversely more likely to achieve cure or remission, researchers say in a new study that sheds light on the gender differences in immune systems.

5 Jul 2024

Pandemic period sees spike in low birth weight among newborns in India

The impact of the coronavirus disease 2019 (COVID-19) pandemic on the incidence of low birth weight (LBW) in India.

5 Jul 2024

Recent advancements and challenges in cervical cancer prevention in China

Recent findings highlight significant advancements and challenges in cervical cancer prevention in China, particularly focusing on rising incidence and mortality rates in rural areas.

4 Jul 2024

Stanford researchers uncover key to overcoming chemoresistance in pancreatic cancer

Pancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy.

4 Jul 2024

Novel compound amplifies naloxone's power to reverse overdoses

In a Stanford Medicine-led study, researchers combed through billions of compounds to find one that could enhance naloxone’s ability to fend off more potent opioids, with promising results in mice.

4 Jul 2024

Late-night REM sleep loss severely impacts brain connectivity, new study reveals

Research reveals that REM sleep deprivation disrupts brain connectivity, with the thalamus playing a key role in sensory information relay and REM sleep regulation.

4 Jul 2024

High ambient temperatures during pregnancy can have detrimental impact on offspring health

As climate change warms the planet, high ambient temperatures are expected to be more common and intense over the coming decades in the U.S. and worldwide.

3 Jul 2024

Repurposing cancer drug to prevent organ damage in infectious diseases

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue.

3 Jul 2024

Decoding cerebellar neural patterns in movement disorders

The cerebellum is a region of the brain that helps us refine our movements and learn new motor skills.

3 Jul 2024

Monocyte signature predicts dexamethasone response in severe COVID-19 patients

Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy.

3 Jul 2024

Researchers identify potential drugs that make naloxone more potent and longer lasting

The ongoing opioid epidemic in the U.S. kills tens of thousands of people every year. Naloxone, sold under the brand name Narcan, has saved countless lives by reversing opioid overdoses.

3 Jul 2024

New guidelines provide the first code of practice for use of stem cell-based embryo models

Stem cell-based embryo models (SCBEMs) are three-dimensional biological structures that mimic aspects of early human embryo development.

3 Jul 2024

Machine learning revolutionizes cardiac studies in fruit flies

Drosophila - commonly known as fruit flies - are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy.

3 Jul 2024

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Antibiotics are a cornerstone of modern medicine. They are regularly used to treat bacterial infections or as a prophylactic measure during surgery to prevent infection.

3 Jul 2024

Research shows the impact of COVID-19 vaccination rates on pediatric asthma symptoms

States with high rates of COVID-19 vaccination saw more pediatric asthma patients get a break from their symptoms, according to new research published today in JAMA Network Open by leaders from Nemours Children's Health and Endeavor Health.

3 Jul 2024

Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

Medicine News and Research

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Why do aortic aneurysms form in specific locations?

DNA repair mutations act as a switch for bowel cancer

Regulatory and psychological considerations of CGM use in people not living with diabetes

Baby boys more likely to achieve HIV cure or remission after in-utero infection

Pandemic period sees spike in low birth weight among newborns in India

Recent advancements and challenges in cervical cancer prevention in China

Stanford researchers uncover key to overcoming chemoresistance in pancreatic cancer

Novel compound amplifies naloxone's power to reverse overdoses

Late-night REM sleep loss severely impacts brain connectivity, new study reveals

High ambient temperatures during pregnancy can have detrimental impact on offspring health

Repurposing cancer drug to prevent organ damage in infectious diseases

Decoding cerebellar neural patterns in movement disorders

Monocyte signature predicts dexamethasone response in severe COVID-19 patients

Researchers identify potential drugs that make naloxone more potent and longer lasting

New guidelines provide the first code of practice for use of stem cell-based embryo models

Machine learning revolutionizes cardiac studies in fruit flies

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Research shows the impact of COVID-19 vaccination rates on pediatric asthma symptoms

Protein nanocages: A promising frontier in mRNA therapeutics

Everything there is to know about biosimilars eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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