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Disruption of actin cytoskeleton is key to triggering human immune response, research finds

Researchers from Cleveland Clinic's Florida Research and Innovation Center (FRIC) found that disruption of a cellular structure, known as the actin cytoskeleton, is a "priming signal" for the body to respond to a virus.

15 Sep 2022

New method evaluates how mutations to SARS-CoV-2 can affect antibody recognition in rapid antigen tests

A research team funded by the National Institutes of Health has shown that commercially available rapid antigen tests can detect past and present variants of concern and has identified potential mutations that may impact test performance in the future.

15 Sep 2022

Gut microbiome associated with multiple sclerosis risk and disease development

An international research consortium led by UC San Francisco scientists has shown significant differences between the gut bacteria profiles of multiple sclerosis (MS) patients and healthy individuals, as well as between MS patients receiving different drug treatments.

15 Sep 2022

Mechanical forces generated by T cells influence the destruction of cancer cells

As a part of our immune defenses, cytotoxic T cells – or killer T cells – seek out and destroy cells that are infected or cancerous. This process is essential for the body's defense against diseases.

15 Sep 2022

Study reveals pan-antiviral properties of PDC-109 bovine seminal plasma protein

In a new study, researchers explored the antiviral activity of the bovine seminal plasma protein PDC-109 against various mammalian viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2022

Development of improved monoclonal antibodies against SARS-CoV-2

In a new study, researchers explored strategies for the development of effective monoclonal antibodies (mAbs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2022

Bivalent recombinant vaccine protects against SARS-CoV-2 and influenza in animal models

In a new study, researchers developed a recombinant bivalent vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses.

15 Sep 2022

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

A new paper discusses the hope held out by recent results on a compound called irisin, a short protein secreted by skeletal muscle that produces some exercise-related effects on the brain.

15 Sep 2022

Mechanism of action of different COVID-19 vaccines

In a recent study posted to the bioRxiv* preprint server, researchers at the University of Tuebingen and Imperial College London assessed humoral and cellular immune responses elicited by the recombinant adenoviral vector (rAdVV)- and messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines.

14 Sep 2022

Defensosomes versus COVID-19

In a recent study published in the journal PLoS Biology, researchers investigated the role of angiotensin-converting enzyme 2 (ACE2)-containing defensive exosomes, or 'defensosomes' against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

14 Sep 2022

Tufts researchers use machine learning to identify new drug cocktails against tuberculosis

Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year.

14 Sep 2022

Large molecules glom together into dense droplets to create squishy circuits in cells

An emerging field explores how groups of molecules condense together inside cells, the way oil droplets assemble and separate from water in a vinaigrette.

14 Sep 2022

Study reveals cellular underpinnings of motor memory acquisition and consolidation

When you are first learning how to ride a bicycle or play a musical instrument, your physical movements are uncoordinated at best.

14 Sep 2022

Scientists harness the potential of bacteria to help create synthetic cells with lifelike functionality

Scientists have harnessed the potential of bacteria to help build advanced synthetic cells which mimic real life functionality.

14 Sep 2022

Neisseria species are linked to worsening bronchiectasis in patients, study shows

A team of international scientists led by the Nanyang Technological University, Singapore (NTU Singapore) has discovered that Neisseria - a genus of bacteria that lives in the human body - is not as harmless as previously thought, and can cause infections in patients with bronchiectasis, asthma, and chronic obstructive pulmonary disease (COPD).

14 Sep 2022

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration.

14 Sep 2022

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

In a new study, researchers investigated the interactions between sirtuin 5 (SIRT5) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein (Nsp14) protein.

14 Sep 2022

Study highlights the efficacy of MVA-BN booster vaccination in inducing durable B cell memory responses against monkeypox

In a new study, researchers assessed the immunogenicity, safety, and booster-efficacy of the Modified Vaccinia virus Ankara-Bavarian Nordic (MVA-BN) vaccine currently being used for immunization against monkeypox.

14 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

The kinetics of T cell response, the inflammatory profile, and the pox-specific T cell induction in monkeypox infection

A new study describes the changes in immune T cell profile over time following monkeypox infection.

14 Sep 2022

B Cell News and Research

Disruption of actin cytoskeleton is key to triggering human immune response, research finds

New method evaluates how mutations to SARS-CoV-2 can affect antibody recognition in rapid antigen tests

Gut microbiome associated with multiple sclerosis risk and disease development

Mechanical forces generated by T cells influence the destruction of cancer cells

Study reveals pan-antiviral properties of PDC-109 bovine seminal plasma protein

Development of improved monoclonal antibodies against SARS-CoV-2

Bivalent recombinant vaccine protects against SARS-CoV-2 and influenza in animal models

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

Mechanism of action of different COVID-19 vaccines

Defensosomes versus COVID-19

Tufts researchers use machine learning to identify new drug cocktails against tuberculosis

Large molecules glom together into dense droplets to create squishy circuits in cells

Study reveals cellular underpinnings of motor memory acquisition and consolidation

Scientists harness the potential of bacteria to help create synthetic cells with lifelike functionality

Neisseria species are linked to worsening bronchiectasis in patients, study shows

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

Study highlights the efficacy of MVA-BN booster vaccination in inducing durable B cell memory responses against monkeypox

What is the impact of COVID-19 treatments targeting intracellular Neu1?

The kinetics of T cell response, the inflammatory profile, and the pox-specific T cell induction in monkeypox infection

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