Clinical Trial News and Research

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Preventing antibiotic side effects: an interview with Florence Séjourné, CEO, Da Volterra

Like all drugs, antibiotics can have side-effects when administered to people. The most common (and often benign) side effect people experience when taking antibiotics is “associated diarrhea”. This illustrates the fact that antibiotics have an impact on the intestine!

25 Jun 2014

Aerie Pharmaceuticals' Roclatan meets all clinical endpoints in Phase 2b trial

Aerie Pharmaceuticals, Inc., a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of first-in-class glaucoma therapies, today reported the successful results of its Phase 2b trial for once-daily, quadruple-action RoclatanTM, a combination of Aerie's triple-action RhopressaTM with latanoprost, a prostaglandin analogue (PGA).

25 Jun 2014

Addition of tomosynthesis to digital mammography increases cancer detection rate

The addition of tomosynthesis, a 3-dimensional breast imaging technique, to digital mammography in more than 170,000 examinations was associated with a decrease in the proportion of patients called back for additional imaging and an increase in the cancer detection rate, according to a study in the June 25 issue of JAMA.

25 Jun 2014

Henry Ford launches clinical trial for treatment of tinnitus caused by noise trauma

Henry Ford Health System has launched a clinical trial to investigate a new drug for the treatment of tinnitus, a chronic ringing of the head or ears that affects more than 600 million people worldwide.

25 Jun 2014

Duke enters into collaboration with BMS to promote open access to clinical information

Duke University, through its Duke Clinical Research Institute (DCRI), announced this week it has entered into a novel collaboration with Bristol-Myers Squibb (BMS) to promote open access to clinical information from company-sponsored studies.

25 Jun 2014

Paralyzed man can move fingers and hand with his own thoughts

For the first time ever, a paralyzed man can move his fingers and hand with his own thoughts thanks to an innovative partnership between The Ohio State University Wexner Medical Center and Battelle.

25 Jun 2014

Sclerosis patients treated with HSCT experience better long-term event-free survival

Among patients with a severe, life-threatening type of sclerosis, treatment with hematopoietic stem cell transplantation (HSCT), compared to intravenous infusion of the chemotherapeutic drug cyclophosphamide, was associated with an increased treatment-related risk of death in the first year, but better long-term survival, according to a study in the June 25 issue of JAMA.

25 Jun 2014

Cardium reports positive results from Generx Ad5FGF-4 Phase 3 study for treatment of myocardial ischemia

Taxus Cardium Pharmaceuticals Group Inc. will report today at the Biotechnology Industry Organization’s 2014 BIO International Convention on a pre-specified interim analysis from its international ASPIRE Phase 3 registration clinical study of Generx Ad5FGF-4, Cardium Therapeutics’ angiogenic gene therapy product candidate for patients with myocardial ischemia due to coronary artery disease.

25 Jun 2014

RYGB surgery can help reduce heart disease risk in obese patients with Type 2 diabetes

Obese patients with Type 2 diabetes who don't have excessive surgical risk may find that Roux-en-Y gastric bypass (RYGB) surgery can help them reduce their risk of heart disease, a new clinical trial shows.

24 Jun 2014

Trevena's Phase 1b data for TRV130 published in the journal Pain

Trevena, Inc., a clinical stage biopharmaceutical company and the leader in the discovery of G protein coupled receptor (GPCR) biased ligands, today announced the publication of its Phase 1b data for TRV130 in the journal Pain.

24 Jun 2014

Computer analysis of family photos could help diagnose rare genetic disorders

Computer analysis of photographs could help doctors diagnose which condition a child with a rare genetic disorder has, say Oxford University researchers.

24 Jun 2014

Researchers devise kinder, gentler way to measure newborns

After their hectic experience of delivery, newborns are almost immediately stretched out on a measuring board to assess their length.

24 Jun 2014

Viewpoints: Concerns about ACOs; problems in Va. gov.'s strategy; Medicaid 'black hole'

Although Obamacare's health insurance expansion has directly provided coverage to only about 4 percent of Americans, changes embedded in the Affordable Care Act could affect many more people, and not always in good ways.

24 Jun 2014

Italian Medicines Agency grants marketing authorization to ILUVIEN for chronic DME treatment

pSivida Corp., a leader in the development of sustained release, drug delivery products for treating eye diseases, today announced that the Italian Medicines Agency (Agenzia Italiana del Farmaco) has granted marketing authorization to ILUVIEN for the treatment of vision impairment associated with chronic diabetic macular edema (DME) considered insufficiently responsive to available therapies.

23 Jun 2014

XenoPort initiates XP23829 Phase 2 clinical trial in patients with psoriasis

XenoPort, Inc. announced today that it has initiated a Phase 2 clinical trial of XP23829, its proprietary investigational next-generation fumaric acid product candidate. The trial is a multi-center, randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of XP23829 as a potential treatment of patients with moderate-to-severe chronic plaque-type psoriasis.

23 Jun 2014

Denosumab increases bone density for postmenopausal women with osteoporosis

Postmenopausal women with osteoporosis who take denosumab long-term have increased bone density, sustained low rate of fractures, and a favorable benefit/risk profile, a new multinational study finds.

23 Jun 2014

Aradigm begins Pulmaquin Phase III study for treatment of non-CF BE

Aradigm Corporation ("Aradigm" or the "Company") today announced the dosing of the first patient in the ORBIT-4 (Once-daily Respiratory Bronchiectasis Inhalation Treatment) Phase III pivotal clinical trial of Aradigm's proprietary formulation of inhaled ciprofloxacin (Pulmaquin®) for the treatment of non-cystic fibrosis bronchiectasis (non-CF BE).

23 Jun 2014

PSI CRO presents the changing dynamic of clinical trial feasibility at PCMG meeting

PSI CRO, a full-service contract research organization, announced today that Kasia Moscicka, Director Feasibility Research and Patient Recruitment Services, presented on the changing dynamic of clinical trial feasibility at recent PCMG meeting held in Lisbon, Portugal.

23 Jun 2014

Trevena reports positive results from TRV734 Phase 1 trial for treating acute/chronic pain

Trevena, Inc. (NASDAQ:TRVN) today announced positive results from its Phase 1 trial of TRV734, which Trevena is developing with the goal of providing improved analgesia while avoiding gastrointestinal and respiratory side effects typically associated with opioids.

23 Jun 2014

Bayer, Dimension Therapeutics partner to develop new gene therapy for hemophilia A

Dimension Therapeutics, a company focused on developing novel adeno-associated virus (AAV) gene therapy treatments for rare diseases, today announced it has entered into a collaboration with Bayer HealthCare (Bayer) for the development and commercialization of a novel gene therapy for the treatment of hemophilia A.

23 Jun 2014

Clinical Trial News and Research

Preventing antibiotic side effects: an interview with Florence Séjourné, CEO, Da Volterra

Aerie Pharmaceuticals' Roclatan meets all clinical endpoints in Phase 2b trial

Addition of tomosynthesis to digital mammography increases cancer detection rate

Henry Ford launches clinical trial for treatment of tinnitus caused by noise trauma

Duke enters into collaboration with BMS to promote open access to clinical information

Paralyzed man can move fingers and hand with his own thoughts

Sclerosis patients treated with HSCT experience better long-term event-free survival

Cardium reports positive results from Generx Ad5FGF-4 Phase 3 study for treatment of myocardial ischemia

RYGB surgery can help reduce heart disease risk in obese patients with Type 2 diabetes

Trevena's Phase 1b data for TRV130 published in the journal Pain

Computer analysis of family photos could help diagnose rare genetic disorders

Researchers devise kinder, gentler way to measure newborns

Viewpoints: Concerns about ACOs; problems in Va. gov.'s strategy; Medicaid 'black hole'

Italian Medicines Agency grants marketing authorization to ILUVIEN for chronic DME treatment

XenoPort initiates XP23829 Phase 2 clinical trial in patients with psoriasis

Denosumab increases bone density for postmenopausal women with osteoporosis

Aradigm begins Pulmaquin Phase III study for treatment of non-CF BE

PSI CRO presents the changing dynamic of clinical trial feasibility at PCMG meeting

Trevena reports positive results from TRV734 Phase 1 trial for treating acute/chronic pain

Bayer, Dimension Therapeutics partner to develop new gene therapy for hemophilia A

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