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Weill Cornell research team develops new experimental drug therapy to target DLBCL

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell - DLBCL (ABC-DLBCL), remains a major therapeutic challenge.

11 Dec 2012

Acetylon announces results from selective HDAC 1/2 inhibitor preclinical study on SCD and bT

Acetylon Pharmaceuticals Inc., a leader in targeted epigenetic drug discovery and development for enhanced therapeutic outcomes, today announced results from a preclinical study of a selective histone deacetylase (HDAC) 1/2 inhibitor for the treatment of sickle cell disease (SCD) and beta-thalassemia (bT) at the 54th Annual Meeting of the American Society of Hematology (ASH), taking place in Atlanta, Georgia.

11 Dec 2012

Childhood obesity: an interview with Professor Clodagh O’Gorman

Childhood obesity is harder to define than adult obesity. This is because any definition of obesity relies on measurements of both height and weight, and the calculation of body mass index (BMI) based on these measurements.

10 Dec 2012

Simple technique based on principles of craniofacial surgery can maximize patient outcomes

As surgical teams gain experience with facial transplantation, a careful approach to planning based on the principles of craniofacial surgery can help to maximize patient outcomes in terms of facial form and function, according to an article in The Journal of Craniofacial Surgery.

10 Dec 2012

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a study from researchers at the University of Michigan Comprehensive Cancer Center.

10 Dec 2012

Ultra-shortened, accelerated breast irradiation treatment logistically achievable and tolerable

Research from The Cancer Institute of New Jersey shows that an ultra-shortened, accelerated breast irradiation treatment using a balloon device is both logistically achievable and tolerable. The work will be offered during a poster presentation at the 35th Annual CTRC-AACR San Antonio Breast Cancer Symposium this week. The Cancer Institute of New Jersey is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School (RWJMS).

7 Dec 2012

NCI-funded study to identify metabolic vulnerabilities of particularly aggressive cancers

Eileen White, PhD, associate director for basic science at The Cancer Institute of New Jersey and professor of molecular biology and biochemistry at Rutgers, The State University of New Jersey, and colleagues from Princeton University have been awarded a new five-year, $2.4 million dollar research grant from the National Cancer Institute.

7 Dec 2012

Disturbances in several immune-system-related pathways contribute to development of ASDs

Researchers using novel approaches and methodologies of identifying genes that contribute to the development of autism have found evidence that disturbances in several immune-system-related pathways contribute to development of autism spectrum disorders.

7 Dec 2012

Gene therapy could represent new treatment option for severe orthopaedic injuries

Gene therapy involving modified stem cells obtained from fatty tissue and bone marrow could represent a new option for the treatment of severe orthopaedic injuries to the extremities.

7 Dec 2012

Longer looks: The frustrations of academic medicine; Small business owners fear health law changes; A doctor struggles to save his mother

Like many franchisees, Robert U. Mayfield, who owns five Dairy Queens in and around Austin, Tex., is always eager to expand and -; no surprise -; has had his eyes on opening a sixth DQ. But he said concerns about the new federal health care law had persuaded him to hold off.

7 Dec 2012

CINJ urologic oncology chief completes 1,000th robotic prostatectomy at RWJUH

Marking a major milestone in what has become a fast-growing standard of care in prostate cancer surgery, the chief of urologic oncology at The Cancer Institute of New Jersey has completed his 1,000th robotic prostatectomy at Robert Wood Johnson University Hospital (RWJUH), the Flagship Hospital of The Cancer Institute of New Jersey, which is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School.

6 Dec 2012

‘Old’ erythrocytes little problem in noncardiac surgery

Erythrocytes that have been stored for several weeks before use may not cause problems in patients who receive transfusions during noncardiac surgery, a large retrospective analysis suggests.

5 Dec 2012

Trouble spot in fiscal talks: The down payment

Although there appears to be general agreement about tax code and entitlement changes that would begin next year and tally more than $1 trillion over 10 years, the initial installment of deficit reduction has become a sticking point between the White House and GOP leaders. Meanwhile, the Washington Post checks the facts on entitlement "spending cuts."

5 Dec 2012

Roundup: Building more Texas medical schools; Calif. mental health care for children

Recommendations in a new draft report on Texas undergraduate medical education caution against rushing to build any new medical schools, which may irk those that are pushing to do exactly that. The report was prepared by the staff of the Texas Higher Education Coordinating Board and posted on the agency's website on Monday in preparation for an upcoming meeting of their Task Force on Graduate Health Professions.

5 Dec 2012

Cabozantinib effectively treats prostate cancer spread to bones

A new drug demonstrated dramatic and rapid effects on prostate cancer that had spread to the bone, according to a study reported by University of Michigan Comprehensive Cancer Center researchers.

5 Dec 2012

Talk is cheap for tackling wasteful emergency diagnostics

An intervention as simple as a staff discussion during a general meeting results in a large reduction in the number of unnecessary diagnostic tests ordered by emergency physicians, say Brazilian researchers.

4 Dec 2012

UK and U.S.researchers collaborate to determine long-term outcomes of children with epilepsy

In the first study of its kind, researchers from five institutions from the UK and U.S. collaborating to determine the long-term outcomes of children with epilepsy found that outcomes varied despite similar short-term morbidity among the originally surveyed children when they were followed up within 10 years post-occurrence.

4 Dec 2012

Hebrew University researchers pave way for development of new approaches to cure malaria

More than a million people die each year of malaria caused by different strains of the Plasmodium parasite transmitted by the Anopheles mosquito. The medical world has yet to find an effective vaccine against the deadly parasite, which mainly affects pregnant women and children under the age of five. By figuring out how the most dangerous strain evades the watchful eye of the immune system, researchers from the Hebrew University of Jerusalem have now paved the way for the development of new approaches to cure this acute infection.

4 Dec 2012

New screening tool to help reduce workplace accidents and illnesses

An international team of sleep researchers has developed the world's first screening tool to help reduce workplace accidents and illnesses, including cardiovascular disease and cancer, caused by shift work.

4 Dec 2012

Viewpoints: Disputing Obama's and GOP's commitment to cutting spending and avoiding fiscal cliff

President Obama has said he wants to reform entitlements eventually, someday, after Republicans raise taxes. Republicans want the President to sign on to serious reform now as part of any deal, since AARP and the left will kill anything that isn't passed immediately. Given the political difficulty of reforming entitlements, Republicans are right to try to get Mr. Obama's fingerprints on such a deal this year.

4 Dec 2012

Medical School News and Research

Weill Cornell research team develops new experimental drug therapy to target DLBCL

Acetylon announces results from selective HDAC 1/2 inhibitor preclinical study on SCD and bT

Childhood obesity: an interview with Professor Clodagh O’Gorman

Simple technique based on principles of craniofacial surgery can maximize patient outcomes

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

Ultra-shortened, accelerated breast irradiation treatment logistically achievable and tolerable

NCI-funded study to identify metabolic vulnerabilities of particularly aggressive cancers

Disturbances in several immune-system-related pathways contribute to development of ASDs

Gene therapy could represent new treatment option for severe orthopaedic injuries

Longer looks: The frustrations of academic medicine; Small business owners fear health law changes; A doctor struggles to save his mother

CINJ urologic oncology chief completes 1,000th robotic prostatectomy at RWJUH

‘Old’ erythrocytes little problem in noncardiac surgery

Trouble spot in fiscal talks: The down payment

Roundup: Building more Texas medical schools; Calif. mental health care for children

Cabozantinib effectively treats prostate cancer spread to bones

Talk is cheap for tackling wasteful emergency diagnostics

UK and U.S.researchers collaborate to determine long-term outcomes of children with epilepsy

Hebrew University researchers pave way for development of new approaches to cure malaria

New screening tool to help reduce workplace accidents and illnesses

Viewpoints: Disputing Obama's and GOP's commitment to cutting spending and avoiding fiscal cliff

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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