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Microglia plays a key role in memory and learning

Immune system cells of the brain, which scavenge pathogens and damaged neurons, are also key players in memory and learning, according to new research by Duke neuroscientists.

27 Oct 2011

U of A researchers discover potential new drug target for MS

Medical researchers at the University of Alberta have discovered a potential new drug target for Multiple Sclerosis that could prevent physical disability associated with the disease, once a new drug is developed.

27 Oct 2011

NCI awards Metabolomx SBIR contract to develop sensor array system for detecting lung cancer

Metabolomx, a diagnostic company focused on breath analysis for the detection of cancer, today announced the Company was awarded a Small Business Innovation Research (SBIR) contract by the National Cancer Institute (NCI). The $1.14 million combined Phase I/II Fast-Track contract will support the research and development of Metabolomx' sensor array system to detect lung cancer.

24 Oct 2011

Comprehensive ADMESeq Research Screening Panel launched

RainDance Technologies, Inc., the Digital Biology Company, and Ambry Genetics, today announced the launch of a comprehensive targeted sequencing panel to screen genes involved with drug absorption, distribution, metabolism, and excretion (ADME) research. The ADMESeq Research Screening Panel enables researchers to simultaneously interrogate 242 known pharmacogenetic genes using next-generation sequencing (NGS) systems.

24 Oct 2011

Small molecule selectively blocks gene activity regulated by thyroid hormone

A small molecule developed at St. Jude Children's Research Hospital advances progress toward more tailored drugs in research that also offers insight into the biology of thyroid hormone.

22 Oct 2011

MRI helps researchers to study molecules directly in organs and tissue

Researchers at Lund University can now study molecules which are normally only found in very small concentrations, directly in organs and tissue. After several years of work, researchers in Lund have managed to construct an instrument that 'hyperpolarises' the molecules and thus makes it possible to track them using MRI.

22 Oct 2011

Researchers identify cancer cell cycle-regulated mechanism

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells.

22 Oct 2011

Romark announces results from NT-300 Phase 2B-3 trial on influenza

Romark Laboratories announced that results of a large Phase 2B-3 US clinical trial of its new flu drug, NT-300 (nitazoxanide), will be presented as an oral late-breaking communication at the 49th Annual Meeting of the Infectious Diseases Society of America (IDSA) being held in Boston, October 20-23, 2011.

22 Oct 2011

Two proteins bind together to ignite and sustain malignant brain tumors

Two previously unassociated proteins known to be overly active in a variety of cancers bind together to ignite and sustain malignant brain tumors, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports this week in the journal Cancer Cell.

22 Oct 2011

Two Philadelphia scientists to receive John Scott Award

Two internationally recognized scientists with strong Philadelphia ties are to receive the John Scott Award this year.

21 Oct 2011

New metabolic pathway for controlling brain inflammation

A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.

21 Oct 2011

Dual role for VEGF in regulating skin cancer stem cells and tumor progression

In a study published in Nature, researchers lead by Cédric Blanpain, MD/PhD, FNRS/FRS researcher and WELBIO investigator at the IRIBHM, Université libre de Bruxelles, Belgium, in collaboration with the groups of Peter Carmeliet (VIB/K.U.Leuven) and Jody J. Haigh (VIB/UGent) identify a new role for Vascular Endothelial Growth Factor (VEGF) in regulating skin cancer stem cells.

21 Oct 2011

Women with MET genetic variant and autoantibodies more likely to have autistic children

A study by researchers at UC Davis has found that pregnant women with a particular gene variation are more likely to produce autoantibodies to the brains of their developing fetuses and that the children of these mothers are at greater risk of later being diagnosed with autism.

20 Oct 2011

Estrogen regulates energy expenditure, appetite and body weight

A recent UT Southwestern Medical Center study found that estrogen regulates energy expenditure, appetite and body weight, while insufficient estrogen receptors in specific parts of the brain may lead to obesity.

20 Oct 2011

JHU, Eisai enter drug-discovery research collaboration for brain disorders

The Johns Hopkins University (JHU) has entered into a drug-discovery research collaboration with Eisai, a pharmaceutical company based in Tokyo, to develop proprietary small-molecule drugs for a range of brain conditions such as schizophrenia, pain, brain tumors and Alzheimer's disease.

20 Oct 2011

Scientists determine structure of GAG proteoglycan

If genes provide the blueprint for life and proteins are the machines that do much of the work for cells, then carbohydrates that are linked to proteins are among the tools that enable cells to communicate with the outside world and each other. But until now, scientists have been unable to determine the structure of a biologically important so-called GAG proteoglycan-or even to agree whether these remarkably complex molecules have well-defined structures.

19 Oct 2011

Link between development of new lymphoid tissue within the lung and protection against TB

New research from the Trudeau Institute may help in the ongoing fight against tuberculosis. Dr. Andrea Cooper's lab has discovered a connection between the development of new lymphoid tissue within the lung and protection against the disease.

19 Oct 2011

New sequencing method can identify genetic variants linked to ASD

Geneticists at Emory University School of Medicine have demonstrated a method that enables the routine amplification of all the genes on the X chromosome. The technology allows the rapid and highly accurate sequencing and identification of novel genetic variants affecting X chromosome genes.

19 Oct 2011

Commercialization strategies for next-generation medicines

The Center for Biotechnology at Stony Brook University, in collaboration with Demy-Colton Life Science Advisors, and key opinion leaders from the biotech and biopharmaceutical industries, academia, medical research foundations, and investment community, has organized a two-day event to forge partnerships to accelerate the development of new treatments for some of the world's most devastating diseases affecting millions.

18 Oct 2011

AR gene has opposite effects on prostate and breast cancers

Researchers at Cleveland Clinic have discovered that a gene - known as an androgen receptor (AR) - is found in both prostate and breast cancers yet has opposite effects on these diseases.

18 Oct 2011