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New research could be first step toward drug to treat Zika infections

New research led by Alexey Terskikh, Ph.D., associate professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), and Alex Strongin, Ph.D., professor at SBP, could be a first step toward a drug to treat Zika infections. Publishing in Antiviral Research, the scientific team discovered a compound that prevents the virus from spreading.

16 May 2017

WSU scientists develop new approach to deliver therapeutics to tumors

For the first time, WSU researchers have demonstrated a way to deliver a drug to a tumor by attaching it to a blood cell. The innovation could let doctors target tumors with anticancer drugs that might otherwise damage healthy tissues.

16 May 2017

New clinical trial to evaluate efficacy of stem cell product in patients disabled with chronic stroke

A clinical trial to evaluate the safety and efficacy of a stem cell product injected directly into the brain to treat chronic motor deficits from ischemic stroke has begun at McGovern Medical School at The University of Texas Health Science Center at Houston.

16 May 2017

European researchers set up new network to boost use of MRI biomarkers in managing kidney disease

Researchers from 22 European countries have set up PARENCHIMA, a network that will boost the use of magnetic resonance imaging biomarkers in efficiently managing chronic kidney disease.

15 May 2017

Penn researchers find AF ablation to be safe and effective for CHD patients

Congenital heart disease (CHD) includes a range of defects that occur in the heart which patients are born with, such as a hole in the heart's wall, a leaky valve or even an inversion in the heart's orientation. CHD was once a severe condition often resulting in early death, but now, more and more CHD patients are living long and healthy lives.

15 May 2017

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Osaka University-led researchers identified differences in how three drugs bind to tumor necrosis factor, a key mediator of inflammatory disease. The team used sedimentation velocity analytical ultracentrifugation to investigate drug-target binding in a physiological environment and at clinically-relevant concentrations.

15 May 2017

Real-world study of robotic PCI shows high success rates for patients across multiple sites

The largest real-world study of robotic percutaneous coronary intervention (PCI) demonstrated clinical and technical success for patients across multiple sites using multiple operators.

12 May 2017

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Tumors, inflammation and circulatory disorders locally disturb the body's acid-base balance. These changes in pH value could be used for example to verify the success of cancer treatments.

12 May 2017

Leti's New Deal project could revolutionize IBD therapies for great benefit of patients in the European Union

Leti, a technology research institute of CEA Tech, today announced a European Union project to develop a nanotherapy targeting the molecules involved in inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis.

12 May 2017

Preclinical data reinforces potential efficacy, durability of investigational gene therapy for DMD

Solid Biosciences announced today that new data from two preclinical studies reinforce the potential of its investigational microdystrophin gene therapy, SGT-001, to be an effective treatment approach for Duchenne muscular dystrophy.

11 May 2017

Study reveals how proline metabolism supports breast cancer metastasis

A multinational group of scientists, led by professor Sarah-Maria Fendt, have discovered that breast cancer cells that have invaded other organs rely on a different nutrient metabolism to produce energy than normal cells and non-metastasizing cancer cells.

11 May 2017

Zinc acetate lozenges may provide 3-fold increase in recovery rate from common cold

According to a meta-analysis of three randomized controlled trials published in Open Forum Infectious Diseases, zinc acetate lozenges may increase the rate of recovery from the common cold three fold. On the fifth day, 70% of the zinc lozenge patients had recovered compared with 27% of the placebo patients.

11 May 2017

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma.

10 May 2017

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Researchers at the University of Cincinnati have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

10 May 2017

Two widely used drugs show effectiveness in treating patients with CRVO-associated macular edema

Monthly eye injections of Avastin (bevacizumab) are as effective as the more expensive drug Eylea (aflibercept) for the treatment of central retinal vein occlusion, according to a clinical trial funded by the National Eye Institute, part of the National Institutes of Health.

10 May 2017

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

A common treatment for asthma, which is the most prevalent chronic childhood disease, requires use of an inhaler. But a big problem with inhalers, used to deliver steroids and other drugs in an aerosol form, is that children often don't operate them properly.

10 May 2017

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

After phase 1 results of Seattle Children's Pediatric Leukemia Adoptive Therapy trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia into complete initial remission, researchers have now opened a first-in-human clinical trial aimed at reducing the rate of relapse after the therapy, which is about 50 percent.

9 May 2017

Maternal education can act as 'social vaccine' for childhood malaria infection, study finds

Every two minutes, a child will die from malaria in Africa. It is a preventable, treatable disease, that each year affects approximately 200 million people globally.

9 May 2017

Elekta Unity introduced transformative magnetic resonance radiation therapy at ESTRO

Through intelligent and pioneering design, Elekta Unity (MR-linac) combines the best of both worlds to create a new paradigm for cancer care and provide extraordinary potential for ‘hard to treat’ cancers.

9 May 2017

Efficacy News and Research

New research could be first step toward drug to treat Zika infections

WSU scientists develop new approach to deliver therapeutics to tumors

New clinical trial to evaluate efficacy of stem cell product in patients disabled with chronic stroke

European researchers set up new network to boost use of MRI biomarkers in managing kidney disease

Penn researchers find AF ablation to be safe and effective for CHD patients

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Real-world study of robotic PCI shows high success rates for patients across multiple sites

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Leti's New Deal project could revolutionize IBD therapies for great benefit of patients in the European Union

Preclinical data reinforces potential efficacy, durability of investigational gene therapy for DMD

Study reveals how proline metabolism supports breast cancer metastasis

Zinc acetate lozenges may provide 3-fold increase in recovery rate from common cold

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Two widely used drugs show effectiveness in treating patients with CRVO-associated macular edema

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

Maternal education can act as 'social vaccine' for childhood malaria infection, study finds

Elekta Unity introduced transformative magnetic resonance radiation therapy at ESTRO

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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