Protein C News and Research

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IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

In a study recently published on the bioRxiv* preprint server, researchers investigated the IFITM2 dependency of SARS-CoV-2 VOCs, including the delta variant for efficient infection.

22 Nov 2021

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

Clonal hematopoiesis, a condition in which mutations associated with blood cancers are found in the blood of healthy people, is common with aging.

22 Nov 2021

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.

22 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Other molecules may have greater potential as cancer therapies than gold complex auranofin

The gold complex auranofin has traditionally been used for treating rheumatism but is also being evaluated as a treatment for certain forms of cancer.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

New score developed to predict outcome in liver cancer patients receiving immunotherapy

There are still no established biomarkers to predict the success of immunotherapy in patients with liver cancer.

22 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

A team of researchers describes the presence of PDCoV strains in plasma samples of three Haitian children with acute undifferentiated febrile illness.

22 Nov 2021

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Turkish researchers discuss their rapid electrochemical biosensing platform to detect the SARS-CoV-2 spike antibody.

22 Nov 2021

COVID-19 multistate outbreak associated with large public gatherings

Researchers from the Centers for Disease Control have investigated a case in Massachusetts that showed a high proportion of vaccine breakthrough infections.

22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

In this interview, News-Medical speaks to Professor Weibke Arlt about her recent research into how the contraceptive pill affects type 2 diabetes in women with PCOS.

22 Nov 2021

CoronaVac vaccine booster strengthens protection against SARS-CoV-2

In a recent study published on the preprint medRxiv* server, an international team of scientists tested CoronaVac as a booster shot and measured its effects on immunity. Their findings showed increases in neutralizing antibodies and T cell response.

21 Nov 2021

Scientists discover several factors influencing waning immunity with the Pfizer COVID Vaccine

New research from Japan found several risk factors associated with greater waning immunity after vaccination. Old age and smoking were amongst those with some of the lowest antibody titers. Women more than men were also more likely to experience a rapid decline in antibody levels 3 to 6 months after receiving their second Pfizer-BioNTech dose.

21 Nov 2021

A canine coronavirus zoonotic spillover and tropism shift

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21 Nov 2021

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists from Nagoya University, Japan, led by Associate Professor Akio Masuda, have recently identified the mechanism behind regulated splicing of large constitutive exons which are rich in disordered regions, and their potential involvement in the assembly of transcription factors.

21 Nov 2021

Importance of cross-neutralizing antibodies against SARS-CoV-2 variants

A new study published in the journal mBio investigates different antibodies from convalescent donors that bind three separate domains of the SARS-CoV-2 spike. The results of this study suggest that the individuals exposed to the SARS-CoV-2 from the first wave have neutralizing antibodies against current variants.

21 Nov 2021

Sheep at low-risk for infection with SARS-CoV-2

A team of scientists from the US has recently evaluated the susceptibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in sheep. The findings reveal that sheep are generally less susceptible to SARS-CoV-2 infection. However, the susceptibility is relatively higher for the alpha variant of the virus. The study is currently available on the bioRxiv preprint server.

21 Nov 2021

Human Proteoform Project aims to define the entire collection of proteins in the body

Now that the Human Genome Project has officially wrapped, an international team of researchers will map the entire collection of proteins in the human body.

21 Nov 2021

Protein C News and Research

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Other molecules may have greater potential as cancer therapies than gold complex auranofin

Paper-based innovations for COVID-19 diagnosis

New score developed to predict outcome in liver cancer patients receiving immunotherapy

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

COVID-19 multistate outbreak associated with large public gatherings

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

CoronaVac vaccine booster strengthens protection against SARS-CoV-2

Scientists discover several factors influencing waning immunity with the Pfizer COVID Vaccine

A canine coronavirus zoonotic spillover and tropism shift

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

Importance of cross-neutralizing antibodies against SARS-CoV-2 variants

Sheep at low-risk for infection with SARS-CoV-2

Human Proteoform Project aims to define the entire collection of proteins in the body

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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