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Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA.

6 Apr 2016

Biopsy detects αSyn in submandibular gland of IRBD patients

Submandibular gland biopsy can be used to identify α-synuclein aggregates, potentially offering not only a simple means of histologically confirming Parkinson's disease but also a marker for the disease in patients with premotor manifestations, researchers report.

5 Apr 2016

$Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture$

Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture

Ethnicity, socioeconomic status and place of residence in the UK all influence the risk of breaking a bone, a new Southampton study has shown.

5 Apr 2016

Familiar gene manages transport of proteins around the cell

How do cells avoid growing topsy-turvy? Growing so your top, front, bottom and back all wind up on the correct side requires a good sense of direction at the cellular level. A Hiroshima University research group has identified a familiar gene with an unexpected role in directing proteins around the cell.

5 Apr 2016

New neurological mechanism can contribute to pain reduction

A UT Dallas scientist has found a new neurological mechanism that appears to contribute to a reduction in pain.

5 Apr 2016

High-quality protein foods could be beneficial for obese people looking to reduce weight

New research published in the Journal of Gerontology: Medical Sciences shows that eating more protein from foods like lean beef, as part of a reduced-calorie diet, can help obese older adults with limited ability to exercise to lose weight and increase physical function. This new research, supported by the Beef Checkoff, contributes to the growing body of evidence that shows lean beef and other high-quality protein foods are beneficial for health, including overweight and obese people looking to reduce weight.

5 Apr 2016

Losmapimod drug fails to meet primary endpoint in clinical trial

Patients taking losmapimod, an anti-inflammatory drug currently being developed, for 12 weeks following a heart attack did not show improvements in the trial's primary endpoint, the rate of cardiovascular death, subsequent heart attack or urgent coronary revascularization, which includes placement of a stent or coronary artery bypass surgery, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

New tool facilitates shared decision-making between physicians and patients with chest pain

Patients visiting a hospital emergency department with chest pain who engaged with their physician in shared decision-making using a tool called Chest Pain Choice showed improved knowledge of their health status and follow-up care options compared with patients who received standard counseling from a physician without the use of this decision aid, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Maternal smoking influences epigenetic programming of unborn child's genetic make-up

If mothers smoke during pregnancy, they influence the epigenetic programming of their unborn child's genetic make-up in the long term. This may give rise to an increased risk of the development of disease risks later in the child's life.

5 Apr 2016

Two common approaches to post-operative AF equally safe, effective

Cleveland Clinic researchers, as part of the Cardiothoracic Surgical Trials Network, have found that two common approaches to post-operative atrial fibrillation - rhythm control and rate control - are equally safe and effective.

5 Apr 2016

Regular exercise can stave off health problems associated with sedentary time

Office workers can stave off health problems associated with sitting down all day by regularly exercising, a new study has found.

5 Apr 2016

Researchers identify blood-based biomarkers to accurately predict suicidal ideation in women

Researchers have identified blood-based biomarkers and developed questionnaire-based apps that may help clinicians identify which of their female patients being treated for psychiatric disorders are at greatest risk of suicidal ideation or behavior.

5 Apr 2016

Study links effects of prenatal alcohol and drug exposure with placental development

In the United States, prenatal alcohol exposure (PAE) is the most common preventable cause of developmental delay. Animal studies have shown some of the adverse effects of PAE on placental development, but few studies have examined these effects in humans. This is the first study to examine the effects of prenatal exposure to methamphetamine, marijuana, and cigarette smoking on human placental development.

5 Apr 2016

Researchers find changes to gender gap in drinking prevalence

Previous research on an apparent narrowing of the historical "gender gap" in drinking prevalence found that girls were more likely to start drinking before 18 years of age compared to boys.

5 Apr 2016

QuietKit unveils new platform to educate users on basics of meditation, mindfulness

QuietKit today announced the launch of its new platform, a website that educates users on the basics of meditation and mindfulness. The website features step-by-step guided meditations to help users develop a habitual practice.

5 Apr 2016

AXT expands preclinical imaging portfolio with addition of inviCRO’s innovative software platforms

AXT has recently bolstered their preclinical and translational imaging products portfolio with the addition of inviCRO’s innovative software platforms.

From AXT Pty Ltd 5 Apr 2016

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Patients treated with CMX-2043--an investigational drug that has previously shown some ability to protect heart muscle from damage during stenting--saw no improved protection in their kidneys compared to placebo, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Researchers explore rapid changes in oxygen levels as aggravating factors in lung failure

Mechanical ventilation can contribute to lung damage by inducing rapid changes in oxygen levels. Researchers at the Medical University of Vienna are now conducting studies for the first time into the significance of these changes as aggravating factors in lung failure.

5 Apr 2016

SymCel joins global initiative to combat antibiotic resistance

Following the global and joint initiative by the pharmaceutical, biotechnology and diagnostics industries this year to combat antibiotic resistance, demand for innovative solutions is especially high. The event took place in January at the World Economic Forum in Davos.

5 Apr 2016

Explaining asthma to children: an interview with Gabe Ortiz MPAS, PA-C

I think the main challenges in explaining asthma to children, is to make them understand that in most instances it may be a chronic condition that might need chronic daily medicine.

5 Apr 2016

Research News and Research

Inflectra (infliximab-dyyb) approved for multiple indications

Biopsy detects αSyn in submandibular gland of IRBD patients

Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture

Familiar gene manages transport of proteins around the cell

New neurological mechanism can contribute to pain reduction

High-quality protein foods could be beneficial for obese people looking to reduce weight

Losmapimod drug fails to meet primary endpoint in clinical trial

New tool facilitates shared decision-making between physicians and patients with chest pain

Maternal smoking influences epigenetic programming of unborn child's genetic make-up

Two common approaches to post-operative AF equally safe, effective

Regular exercise can stave off health problems associated with sedentary time

Researchers identify blood-based biomarkers to accurately predict suicidal ideation in women

Study links effects of prenatal alcohol and drug exposure with placental development

Researchers find changes to gender gap in drinking prevalence

QuietKit unveils new platform to educate users on basics of meditation, mindfulness

AXT expands preclinical imaging portfolio with addition of inviCRO’s innovative software platforms

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Researchers explore rapid changes in oxygen levels as aggravating factors in lung failure

SymCel joins global initiative to combat antibiotic resistance

Explaining asthma to children: an interview with Gabe Ortiz MPAS, PA-C

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