Efficacy News and Research

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BGRF scientists help develop AI to expedite drug development for age-related conditions

The Chief Science Officer of the Biogerontology Research Foundation will present new research on artificial intelligence for drug discovery at the NVIDIA Graphics Technology Conference at the San Jose Convention Center, on Wednesday, May 10, 1:00 PM - 1:50 PM alongside two AI scientists from the BGRF and Insilico Medicine, where they will deliver a presentation titled "Applications of Generative Adversarial Networks to Drug Discovery in Oncology and Infectious Diseases".

9 May 2017

UAB symposium highlights use of tissue engineering to repair broken hearts

The third annual Cardiovascular Tissue Engineering Symposium met at the University of Alabama at Birmingham last month, a gathering of noted physicians and scientists who share the goal of creating new tissues and new knowledge that can prevent or repair heart disease and heart attacks.

9 May 2017

New UCI Malaria Initiative aims to disrupt deadly disease transmission in Africa

University of California, Irvine vector biologist Anthony James will lead a multimillion-dollar effort to cultivate new strains of mosquitoes to fight malaria in Africa.

9 May 2017

WHO to launch pilot project for prequalifying biosimilar cancer medicines

This year WHO will launch a pilot project for prequalifying biosimilar medicines, a step towards making some of the most expensive treatments for cancer more widely available in low- and middle-income countries.

8 May 2017

Precise delivery of HDR brachytherapy provides good quality of life to prostate cancer patients

Doctors have found that treating prostate cancer with a single, high dose of radiation delivered precisely to the site of the tumor results in good quality of life and fewer trips to the hospital, with adverse side effects that are no worse than if the radiation treatment had been given in several lower doses.

8 May 2017

FDA approves new treatment for people with ALS

The U.S. Food and Drug Administration today approved Radicava (edaravone) to treat patients with amyotrophic lateral sclerosis, commonly referred to as Lou Gehrig's disease.

5 May 2017

Researchers find new way to make influenza visible to the naked eye

Researchers at the University of Notre Dame have discovered a way to make influenza visible to the naked eye, according to a new study in the Journal of the American Chemical Society.

5 May 2017

Study reveals swearing provides tolerance toward pain and makes individuals stronger

The study conducted by Dr Richard Stephens, from Keele University, and David Spierer and Emmanuel Katehis, from Long Island University Brooklyn, reveals that swearing aloud makes individuals stronger.

5 May 2017

Study: Use of white blood cell boosting drugs found to be safe during chemo-radiotherapy of lung cancer

A late breaking subanalysis of the phase III CONVERT trial presented at the European Lung Cancer Conference shows that white blood cell boosting drugs are safe during concurrent chemo-radiotherapy of small cell lung cancer (SCLC).

5 May 2017

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Already extolled for their health benefits as a food compound, omega-3 fatty acids now appear to also play a critical role in preserving the integrity of the blood-brain barrier, which protects the central nervous system from blood-borne bacteria, toxins and other pathogens, according to new research from Harvard Medical School.

5 May 2017

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

The University of Alabama at Birmingham and two partner institutions have received a European patent for their novel approach to fighting cancer, an approach that is led by the UAB spinoff biopharmaceutical company Incysus Ltd.

5 May 2017

Researchers develop hybrid nanomaterial for destruction of cancer cells

Most tumors contain regions of low oxygen concentration where cancer therapies based on the action of reactive oxygen species are ineffective.

4 May 2017

$New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds$

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

A team of researchers of the University of Barcelona and the Hospital del Mar Medical Research Institute have discovered a new mutation that has an impact on the bone so that it is vulnerable to the bisphosphonate, a drug used to treat osteoporosis.

4 May 2017

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

The disease is characterized by inflammation and a buildup of tissue around the eyes that cause them to bulge painfully from their sockets.

4 May 2017

New treatment offers hope for kidney failure and transplant patients with rare disorder

A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.

3 May 2017

Zinc acetate and zinc gluconate lozenges show similar efficacy in shortening duration of common colds

There is no significant difference between zinc acetate lozenges and zinc gluconate lozenges regarding their efficacy in shortening the duration of common colds according to a meta-analysis published in Journal of the Royal Society of Medicine Open.

3 May 2017

Researchers identify key player in initiation and progression of melanoma

Identification and functional validation of proteins involved in tumorigenesis are essential steps toward advancing cancer precision medicine. In The Journal of Clinical Investigation researchers from VIB, KU Leuven together with colleagues from INSERM now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

3 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

Merck announced the presentation of new analyses of efficacy and safety data for investigational Cladribine Tablets in poster presentations at the Annual Meeting of the American Academy of Neurology (AAN), that took place April 22 – 28, 2017, in Boston, Massachusetts.

3 May 2017

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

Shire plc and Parion Sciences, Inc. have announced they have entered into an agreement granting Shire exclusive worldwide rights to develop and commercialize P-321. Shire will lead development of P-321, an investigational epithelial sodium channel (ENaC) inhibitor for the potential treatment of dry eye disease in adults, with the opportunity for Parion to co-fund.

3 May 2017

Efficacy News and Research

BGRF scientists help develop AI to expedite drug development for age-related conditions

UAB symposium highlights use of tissue engineering to repair broken hearts

New UCI Malaria Initiative aims to disrupt deadly disease transmission in Africa

WHO to launch pilot project for prequalifying biosimilar cancer medicines

Precise delivery of HDR brachytherapy provides good quality of life to prostate cancer patients

FDA approves new treatment for people with ALS

Researchers find new way to make influenza visible to the naked eye

Study reveals swearing provides tolerance toward pain and makes individuals stronger

Study: Use of white blood cell boosting drugs found to be safe during chemo-radiotherapy of lung cancer

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

Researchers develop hybrid nanomaterial for destruction of cancer cells

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

New treatment offers hope for kidney failure and transplant patients with rare disorder

Zinc acetate and zinc gluconate lozenges show similar efficacy in shortening duration of common colds

Researchers identify key player in initiation and progression of melanoma

Scientists map genetic changes that help drive aggressive brain tumor

Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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