Genome News and Research

RSS

PDGFR gene rearrangements lead to aggressive form of glioblastoma: Study

4 Oct 2010

UCLA receives contract to study proteins involved in cardiovascular disease development

UCLA has received a five-year, $12.5 million contract award from the National Heart, Lung and Blood Institute to spearhead an international consortium of medical experts that will study proteins that may be involved in the development of cardiovascular disease.

4 Oct 2010

Activating rearrangements in receptor genes are more common than previously thought

A multi-institutional team led by investigators from Memorial Sloan-Kettering Cancer Center has published a study that provides new insight into genetic changes that make some forms of glioblastoma, the most common type of primary brain cancer, more aggressive than others and explains why they may not respond to certain therapies. The research was led by senior author Eric C. Holland, MD, PhD,--an MSKCC surgeon, researcher and the Director of the Brain Tumor Center--and was published in the October 1 issue of the journal Genes & Development.

1 Oct 2010

Report finds development of multiple myeloma is tied to 'hypomethylation'

DNA methylation - a modification of DNA linked to gene regulation - is altered with increasing severity in a blood cancer called multiple myeloma, according to a study by Mayo Clinic and the Translational Genomics Research Institute (TGen).

1 Oct 2010

Albert Einstein College of Medicine receives grant to study role of proteins in health and disease

The National Institute of General Medical Sciences (NIGMS) has awarded Albert Einstein College of Medicine of Yeshiva University a five-year, $30 million grant to study the structure and function of thousands of biomedically important proteins.

1 Oct 2010

Researchers discover new factors that regulate fat formation

By creating a "map" of histone modifications in fat cells, investigators have discovered two new factors that regulate fat formation, a key step on the road to better understanding obesity, diabetes and other metabolic disorders.

1 Oct 2010

Agilent introduces SureSelect Kinome Target Enrichment Kit to focus next-generation sequencing studies

Agilent Technologies Inc. today introduced the SureSelect Kinome Target Enrichment Kit, enabling researchers to focus next generation sequencing studies on expressed kinases (the kinome). Researchers increasingly are looking at human kinases as a rich, proven source of biomarkers as well as potential drug targets for cancers and other diseases.

30 Sep 2010

McLean Researchers receive award to create first clinic-ready human induced iPS cells

Belmont, MA-Researchers at Harvard Affiliated McLean Hospital have been awarded a $1.9 million National Institutes of Health Director's Opportunity Award to continue their research into creating human induced pluripotent (iPS) stem cells using a method aimed at eliminating the risk of cancer and other problems associated with other options such as genome-integrating viral methods.

30 Sep 2010

Researchers receive NIH award to investigate regenerative potential of retinal cells

Zhang and co-principal investigators Sheng Ding, PhD, from The Scripps Research Institute, and Thomas Reh, PhD from the University of Washington, received the highest possible scores for their proposal to investigate the regenerative potential of retinal cells. Their long-term goal is to restore visual function lost through diseases such as macular degeneration and retinitis pigmentosa.

30 Sep 2010

Researchers discover genes that influence human height

An international team of researchers, including a number from the University of North Carolina at Chapel Hill schools of medicine and public health, have discovered hundreds of genes that influence human height.

30 Sep 2010

Morphotek announces first therapeutic monoclonal antibody for clinical development

Morphotek, Inc., a subsidiary of Eisai Inc., today announced that a monoclonal antibody has been selected for advancement to clinical development under the terms of its March 2009 collaboration agreement with Human Genome Sciences, Inc.

29 Sep 2010

Researchers unveil mechanism of candida infections

More than half of all people are hosts to Candida albicans in their bodies. This species might be located on their skin or mucous membranes or in the intestines frequently without causing any symptoms. However, it can be dangerous to patients whose immunological system has been weakened such as after organ transplants or chemotherapy with cancer. Then, this fungus penetrates into deeper layers of tissue and uses the blood system to spread throughout the body. In Germany alone, several thousand people die from systemic candida infections every year.

29 Sep 2010

Scientists discover way of shrinking tumours in cancers

Australian and American scientists have found a way of shrinking tumours in certain cancers - a finding that provides hope for new treatments.

29 Sep 2010

Covaris enters co-marketing partnership with Illumina for DNA shearing technologies

Covaris Inc. today announced that it has signed a co-marketing agreement with Illumina, Inc. making Covaris DNA shearing technologies the recommended method of shearing with Illumina next-generation sequencing product lines, including HiSeq, HiScanSQ, and Genome Analyzer.

From Illumina, Inc. 29 Sep 2010

Scientists to identify microbial risk predictors for preterm birth

A team of scientists from Mayo Clinic, the University of Illinois at Urbana-Champaign, and the J. Craig Venter Institute are leveraging a long-standing research relationship to apply results from the Human Microbiome Project to help identify microbial risk predictors for preterm birth.

29 Sep 2010

Researchers find genetic variants that cause arthritis in breast cancer patients taking aromatase inhibitors

Mayo Clinic researchers and their international colleagues have discovered genetic variants that lead to severe arthritis for a subset of women when taking aromatase inhibitors to treat their breast cancer. This serious side effect is so painful that many women halt their lifesaving medication. The findings appear today in the online issue of Journal of Clinical Oncology.

28 Sep 2010

GATC Biotech to apply Illumina's HiSeq 2000 for human genome analysis

Within the next four years GATC Biotech plans to analyse 100,000 human genomes in particular for the pharmaceutical and diagnostic industry as well as for academic research. This will be realised by applying Illumina's HiSeq 2000 as well as GATC Biotech's latest acquisition, the single molecule sequencing platform PacBio RS.

28 Sep 2010

Tel Aviv researchers develop innovative software to analyze and manipulate diseased cells

About ten years ago, the discovery of microRNAs ― tiny cellular molecules that regulate our genetic code ― unlocked a world of scientific possibilities, including a deeper understanding of human disease. One new analytical technology is "deep sequencing," which gives scientists the ability to discover invaluable information about human diseases at a genetic level.

28 Sep 2010

Study: Genetic ancestry has no influence on how African-Americans with asthma respond to medication

Genetic ancestry has no discernible influence on how African American patients with asthma respond to medication, according to a Henry Ford Hospital study.

28 Sep 2010

OpGen completes Series B equity financing

OpGen, Inc., a commercial phase genomics company, today announced the successful completion of a $17 million Series B equity financing.

28 Sep 2010

Genome News and Research

PDGFR gene rearrangements lead to aggressive form of glioblastoma: Study

UCLA receives contract to study proteins involved in cardiovascular disease development

Activating rearrangements in receptor genes are more common than previously thought

Report finds development of multiple myeloma is tied to 'hypomethylation'

Albert Einstein College of Medicine receives grant to study role of proteins in health and disease

Researchers discover new factors that regulate fat formation

Agilent introduces SureSelect Kinome Target Enrichment Kit to focus next-generation sequencing studies

McLean Researchers receive award to create first clinic-ready human induced iPS cells

Researchers receive NIH award to investigate regenerative potential of retinal cells

Researchers discover genes that influence human height

Morphotek announces first therapeutic monoclonal antibody for clinical development

Researchers unveil mechanism of candida infections

Scientists discover way of shrinking tumours in cancers

Covaris enters co-marketing partnership with Illumina for DNA shearing technologies

Scientists to identify microbial risk predictors for preterm birth

Researchers find genetic variants that cause arthritis in breast cancer patients taking aromatase inhibitors

GATC Biotech to apply Illumina's HiSeq 2000 for human genome analysis

Tel Aviv researchers develop innovative software to analyze and manipulate diseased cells

Study: Genetic ancestry has no influence on how African-Americans with asthma respond to medication

OpGen completes Series B equity financing

Genetics & Genomics - Second Edition eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News