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New chemical probe could tag cells for detection by MRI

The need to non-invasively "see" and track cells in living persons is indisputable - a boon to both research and development of future therapies. Emerging treatments using stem cells and immune cells are poised to most benefit from cell tracking, which would visualize their behavior in the body after delivery. Clinicians require such data to speed these cell treatments to patients.

15 Mar 2016

One-fourth of seniors acquire new superbugs during hospital stay

One in four seniors is bringing along stowaways from the hospital to their next stop: superbugs on their hands.Moreover, seniors who go to a nursing home or other post-acute care facility will continue to acquire new superbugs during their stay, according to findings made by University of Michigan researchers published today in a JAMA Internal Medicine research letter.

15 Mar 2016

ZYTIGA plus prednisone provides overall survival benefit in men with early and less aggressive mCRPC

Janssen-Cilag International NV today announced that data from a post-hoc analysis of the Phase 3 COU-AA-302 trial showed that ZYTIGA (abiraterone acetate) plus prednisone provided an 11.8 months overall survival (OS) benefit (53.6 months vs 41.8 months; HR = 0.61 [95% CI, 0.43-0.87]; p = 0.0055), compared to an active control of placebo plus prednisone, in men with early and less aggressive chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC).

15 Mar 2016

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Addition of lapatinib to trastuzumab improves responses in women with newly diagnosed, HER2-positive breast cancer who receive the combination prior to undergoing surgery, suggests research.

14 Mar 2016

Researchers identify potential drug target in skin for itchy feeling

No matter the trigger -- bug bites, a medication side-effect or an itchy wound -- the urge to scratch can be a real pain. Researchers at the Duke University Medical Center have identified a potential drug target in the skin for that itchy feeling.

14 Mar 2016

Research finds new molecular details of facultative stem cells

In a study published this week in PLOS Genetics, scientists Nareg J. Djabrayan and Jordi Casanova from the Institute for Research in Biomedicine and CSIC, have identified two molecular signals and the pathway of events that allows cells in a tissue that are already specialized to regain their behaviour as stem cells.

14 Mar 2016

Population health research on cardiovascular health finds positive results

In 2009, Minneapolis Heart Institute Foundation, along with Allina Health, New Ulm Medical Center and the community of New Ulm, Minnesota, began a 10-year population health research project to learn if heart attacks and heart disease risk factors within a community could be decreased through community efforts. Results for the first five years have been released, and the initial findings are positive.

14 Mar 2016

Real maple syrup shows promise in protecting brain health

As part of a two-day symposium at the annual meeting of the American Chemical Society, a group of international scientists shared promising results of 24 studies exploring the beneficial effects of natural products on the prevention of neurodegenerative diseases, particularly Alzheimer's disease.

14 Mar 2016

Newly developed biodegradable polymer grafts can help repair the spine

Remember those colorful "grow capsules" that blossom into animal-shaped sponges in water? Using a similar idea, scientists have developed biodegradable polymer grafts that, when surgically placed in damaged vertebrae, should grow to be just the right size and shape to fix the spinal column.

14 Mar 2016

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

NASA limits an astronaut's radiation exposures to doses that keep their added risk of fatal cancer below 3 percent. Unfortunately, that ceiling restricts the time an astronaut may spend in space, which in turn restricts the ability to perform longer missions, say a mission to Mars.

14 Mar 2016

Scientists develop prototype sensor system for remote detection of dangerous gases

Scientists at the Universitat Politécnica de València and the Universidad Politécnica de Madrid have developed a prototype sensor system which not only allows the remote detection of dangerous gases (CO, NO, NO2), but can estimate their concentration levels.

14 Mar 2016

BioSpecifics reports net income of $2.7 million for fourth quarter 2015

BioSpecifics Technologies Corp., a biopharmaceutical company that originated and continues to develop collagenase based-therapies with a first in class collagenase-based product collagenase clostridium histolyticum, or CCH, marketed as XIAFLEX in the U.S. and Xiapex in Europe, today announced its financial results for the fourth quarter and full year ended December 31, 2015 and provided a corporate update.

14 Mar 2016

Research: Sedentary behaviour increases in physically active children

Sedentary behaviour increases in children between the ages of nine and 12 - even if they are otherwise physically active, according to research at the Universities of Strathclyde and Newcastle.

14 Mar 2016

Paroxysmal AF patients who practice yoga have better quality of life

Yoga improves quality of life in patients with paroxysmal atrial fibrillation, according to research published today in the European Journal of Cardiovascular Nursing. Heart rate and blood pressure also decreased in patients who did yoga.

14 Mar 2016

Could environmental toxins trigger amyloid plaques in the brain? An interview with Dr Paul Alan Cox

Many Chamorro villagers on the island of Guam perished from a puzzling paralytic disease that combines aspects of ALS, Alzheimer's, and Parkinson's disease.

From Huron Technologies 14 Mar 2016

Researchers examine effects of family-centred neonatal discharge planning process

Researchers from the University of Bristol have found new parents benefit from help to prepare them to bring their premature babies home from hospital.

14 Mar 2016

Use of contralateral prophylactic mastectomy tripled from 2002 to 2012 despite no survival benefit

The use of contralateral prophylactic mastectomy (CPM), the surgical removal of a breast unaffected by cancer as part of the course of treatment for breast cancer, has more than tripled from 2002 to 2012 despite evidence suggesting no survival benefit over breast conservation, according to a new study from Brigham and Women's Hospital published in Annals of Surgery on March 11, 2016.

14 Mar 2016

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Building upon earlier research, investigators at UT Southwestern Medical Center and their collaborators have identified a new innate immunity pathway that protects mammals from viral oncogenesis, the process by which viruses cause normal cells to become cancerous.

14 Mar 2016

TRPV2 could be a target for obesity therapy

Brown adipose tissue (BAT), a major site for mammalian non-shivering thermogenesis, could be a target for prevention and treatment of human obesity. Transient receptor potential vanilloid 2 (TRPV2), a Ca2+-permeable cation channel, plays vital roles in the regulation of various cellular functions.

14 Mar 2016

NIMH-supported researchers discover key secrets of the underlying brain circuitry

A few years ago, researchers supported by the National Institutes of Health discovered in rats that awake mental replay of past experiences is critical for learning and making informed choices. Now, the team has discovered key secrets of the underlying brain circuitry -- including a unique system that encodes location during inactive periods.

14 Mar 2016

Research News and Research

New chemical probe could tag cells for detection by MRI

One-fourth of seniors acquire new superbugs during hospital stay

ZYTIGA plus prednisone provides overall survival benefit in men with early and less aggressive mCRPC

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Researchers identify potential drug target in skin for itchy feeling

Research finds new molecular details of facultative stem cells

Population health research on cardiovascular health finds positive results

Real maple syrup shows promise in protecting brain health

Newly developed biodegradable polymer grafts can help repair the spine

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

Scientists develop prototype sensor system for remote detection of dangerous gases

BioSpecifics reports net income of $2.7 million for fourth quarter 2015

Research: Sedentary behaviour increases in physically active children

Paroxysmal AF patients who practice yoga have better quality of life

Could environmental toxins trigger amyloid plaques in the brain? An interview with Dr Paul Alan Cox

Researchers examine effects of family-centred neonatal discharge planning process

Use of contralateral prophylactic mastectomy tripled from 2002 to 2012 despite no survival benefit

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

TRPV2 could be a target for obesity therapy

NIMH-supported researchers discover key secrets of the underlying brain circuitry

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