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Modified therapeutic molecule enhances stroke treatment

A research team from the Institut national de la recherche scientifique (INRS) has improved the protective effect of a molecule against ischemic stroke, which is caused by an interruption of blood flow to the brain.

18 Feb 2021

Are antibody cocktails the key to COVID-19 treatment?

News-Medical speaks to Dr. Natalia Freund about her latest research into COVID-19, and how most people are capable of producing neutralizing antibodies against the virus.

18 Feb 2021

Scientists reveal the structure of glutamate transporter in our cells

For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical signals from one cell to another.

18 Feb 2021

Scientists reveal the shape of glutamate transporter in human cells

A University of Sydney-led international team of scientists has revealed the shape of one of the most important molecular machines in our cells the glutamate transporter, helping to explain how our brain cells communicate with one another.

18 Feb 2021

Engineered peptide can reduce severe COVID-19 infection in humans

An engineered peptide given to ferrets two days before they were co-housed with SARS-CoV-2-infected animals prevented virus transmission to the treated ferrets, a new study shows.

18 Feb 2021

New insights on structural biology may help design more efficient antibodies

In structural biology, some molecules are so unusual they can only be captured with a unique set of tools.

18 Feb 2021

Opioid supply-controlling policies may have unintended consequences, finds study

In response to the increase in opioid overdose deaths in the United States, many states have implemented supply-controlling and harm-reduction policy measures aimed at reducing those deaths.

17 Feb 2021

$1.3 million grant funds clinical trial to test psilocybin for treating patients with phantom limb pain

The Psychedelics and Health Research Initiative at UC San Diego has received a $1.3 million grant from the Steven & Alexandra Cohen Foundation to fund a clinical trial investigating the therapeutic potential of psilocybin in treating phantom limb pain.

17 Feb 2021

Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma

In people with central nervous system (CNS) lymphoma, cancerous B cells--a type of white blood cell--accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels.

17 Feb 2021

FDA approves novel 3D-printed talus implant for humanitarian use

Today, the U.S. Food and Drug Administration approved the Patient Specific Talus Spacer 3D-printed talus implant for humanitarian use.

17 Feb 2021

Rebate systems may hamper patient access to drugs

Pharmaceutical manufacturers and national authorities often negotiate secret rebates when determining drug prices. A UZH study shows that these rebate systems may hamper patient access to drugs. In the medium term, this practice can even lead to increasing drug prices.

17 Feb 2021

Researchers track how Osmium reacts in a single cancer cell

Osmium is a rare precious metal that could be used to treat cancer with fewer side effects when compared to Platinum, currently used in nearly half of chemotherapies.

17 Feb 2021

Researchers identify molecular link between inflammatory signaling molecule and a main oncogene

A team of MedUni Vienna researchers led by Johannes A. Schmid at the Center for Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, has managed to identify a previously unknown molecular connection between an inflammatory signaling molecule and one of the main oncogenes.

17 Feb 2021

Development of malaria vaccines deserves urgent attention just like COVID-19

Developing vaccines to fight malaria deserves urgent attention just like COVID-19, argues Damaris Matoke-Muhia.

17 Feb 2021

$Study investigates fracture-associated drug use among long-term care residents$

Study investigates fracture-associated drug use among long-term care residents

Findings from a new Geisel-led study, published in the Journal of General Internal Medicine, reveal that there is substantial variation across different regions of the country in the intensity of fracture-associated drug (FAD) use among long-term care facility residents, and that areas with greater use of these prescription drugs experience higher hip fracture rates.

17 Feb 2021

Study highlights promising opportunities that may reduce wasteful health care spending

Spending on low-value health care among fee-for-service Medicare recipients dropped only marginally from 2014 to 2018, despite both a national campaign to better educate clinicians and increasing use of payment revisions that discourage wasteful care, according to a new RAND Corporation study.

17 Feb 2021

Study shows how SARS-CoV-2 uses an immune system defense for replication

The immune system actually wants to fight SARS-CoV-2 with antiviral signaling molecules. But a research team from Charité and MDC has now shown how such a signaling molecule can promote the replication of the virus. The results have been published in the journal EMBO Molecular Medicine.

17 Feb 2021

Mathematical model reveals how cell turnover determines the success of adaptive therapy

One of the most challenging issues in cancer therapy is the development of drug resistance and subsequent disease progression.

17 Feb 2021

Antibody effector functions are crucial part of treating COVID-19 infections

Of the nine treatments and preventives for COVID-19 authorized for emergency use by the Food and Drug Administration, three are drugs made from so-called monoclonal antibodies.

17 Feb 2021

Understanding stroke and heart disease in women remains a major research priority

Understanding the sex differences in cardiovascular disease presentation and outcomes remains a major research priority demonstrated by the record number of submissions for this year's Go Red for Women® special issue of the American Heart Association's flagship journal Circulation, published online today.

17 Feb 2021