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Scientists examine DNA repair pathways and their impact on cancer evolution

DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers.

17 Feb 2021

Study reveals the therapeutic applications of medicinal plants

Both Asia and Africa are home to many plants that can be used for the treatment of many diseases and their medicinal properties are gaining interest in western societies.

17 Feb 2021

A new method for controlling leukemic stem cells

Leukemia is caused by leukemic stem cells which are resistant to most known therapies. Relapses are also due to this resistance. Leukemic stem cells arise from normal blood-forming (hematopoietic) stem cells.

17 Feb 2021

Noninvasive brain stimulation restores behavioral flexibility in cocaine-exposed rats

A major impediment to treatment of substance use disorder (SUD) is a loss of behavioral flexibility, whereby one's judgment is impaired such that their actions continuously result in negative consequences.

16 Feb 2021

Study outlines the reasons to test pediatric cancer patients for inherited genes

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

16 Feb 2021

Combining lipid-lowering drugs and lifestyle interventions may yield greatest heart-protecting benefits

Combining healthy lifestyle interventions reduces heart disease through beneficial effects on different lipoproteins and associated cholesterols, according to a study published February 9 in eLife.

16 Feb 2021

Scientists discover two unique subtypes of a prominent mutation in patients with AML

Using advanced RNA sequencing, scientists have identified two unique subtypes of a prominent mutation present in many patients with Acute Myeloid Leukemia (AML) – called NPM1 – that could help predict survival and improve treatment response for patients whose leukemic cells bear the mutation.

16 Feb 2021

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and develop prediabetes and hyperinsulemia?

15 Feb 2021

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

Recreational drinking, smoking, and drug use is linked to premature heart disease in young people, particularly younger women, finds research published online in the journal Heart.

15 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

How SARS-CoV-2 enters the central nervous system

The central nervous system (CNS) is highly protected in the human body. Yet, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the CNS, causing profound clinical complications. How is the CNS involved in a respiratory virus infection?

15 Feb 2021

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

15 Feb 2021

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

A paper published today in Nature shows how chemicals in the areas surrounding tumors--known as the tumor microenvironment--subvert the immune system and enable cancer to evade attack. These findings suggest that an existing drug could boost cancer immunotherapy.

15 Feb 2021

Drugs News and Research

Scientists examine DNA repair pathways and their impact on cancer evolution

Study reveals the therapeutic applications of medicinal plants

A new method for controlling leukemic stem cells

Noninvasive brain stimulation restores behavioral flexibility in cocaine-exposed rats

Study outlines the reasons to test pediatric cancer patients for inherited genes

Combining lipid-lowering drugs and lifestyle interventions may yield greatest heart-protecting benefits

Scientists discover two unique subtypes of a prominent mutation in patients with AML

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

How SARS-CoV-2 enters the central nervous system

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

Existing heart failure drug may be effective in treating postural orthostatic tachycardia syndrome

Scientists discover new immunotherapy target for malignant brain tumors

Benjamin L. Ebert receives Sjöberg Prize for breakthrough research on blood cancer

LifeArc supports the GenOMICC COVID-19 Study

Immunosuppressive therapies may be linked to severe COVID-19 in those with multiple sclerosis

Can Pfizer and Moderna end the pandemic by sharing their vaccine designs? It’s not that simple

A machine learning approach to identify drugs that could be repurposed to fight COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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