Immune System News and Research

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Researchers develop new compound that can take down defenses in M. tuberculosis

Part of the reason tuberculosis-causing bacteria are so good at colonizing the human body is that they have defenses against the body's immune system.

6 Dec 2016

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells.

6 Dec 2016

Dual therapy safe and effective in patients with recurrent Hodgkin lymphoma

The combination of two new drugs that harness the body's immune system is safe and effective, destroying most cancer cells in 64 percent of patients with recurrent Hodgkin lymphoma, according to the results of an early-phase study.

6 Dec 2016

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Autism spectrum disorder is caused by a variety of factors, both genetic and environmental.

5 Dec 2016

Research validates effectiveness of world-first dental vaccine

A world-first vaccine developed by Melbourne scientists, which could eliminate or at least reduce the need for surgery and antibiotics for severe gum disease, has been validated by research published this weekend in a leading international journal.

5 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Researchers are reporting the highest and most sustained levels to date of the essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B.

4 Dec 2016

ACS approves $1.7 million funding for new research grants to Yale University

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding for three new research grants totaling over $1.7 million to investigators at Yale University.

2 Dec 2016

New FDA-approved drug helps patients fight against late-stage lung cancer

A new drug has been approved by the FDA in the fight against lung cancer. Tecentriq is being used by patients like Cornelius Bresnan, who had late-stage cancer.

2 Dec 2016

Cornell researchers develop chemical probe activated by UV light to control inflammation

Black light does more than make posters glow. Cornell researchers have developed a chemical tool to control inflammation that is activated by ultraviolet (UV) light.

2 Dec 2016

Researchers show how microRNAs play key role in tumor progression and response to radiation

OHSU researcher Sudarshan Anand, Ph.D., has a contemporary analogy to describe microRNA: "I sometimes compare MicroRNA to tweets -- they're short, transient and constantly changing."

2 Dec 2016

Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists and medics have developed a promising new test to identify patients with a rare liver disease who will not respond to standard treatment, allowing earlier intervention with alternatives.

2 Dec 2016

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular "off" switch for the inflammatory immune response that contributes to lung-constricting asthma attacks.

2 Dec 2016

New UGA research finds pathogen's motility activates immune response

Until now, a pathogen's ability to move through the body has been overlooked as a possible trigger of immune response, but new research from the University of Georgia College of Veterinary Medicine found that motility will indeed alarm the host and activate an immune response.

1 Dec 2016

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs.

1 Dec 2016

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells.

1 Dec 2016

Study suggests new approach to treat white blood cells of sepsis patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria.

1 Dec 2016

New device could revolutionize drug delivery to treat cancer and other diseases, study shows

A new study by Lyle Hood, assistant professor of mechanical engineering at The University of Texas at San Antonio, describes a new device that could revolutionize the delivery of medicine to treat cancer as well as a host of other diseases and ailments.

1 Dec 2016

Duke researchers modify popular drug-delivery technology to evade immune responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials.

1 Dec 2016

Type 2 diabetes drug may someday help combat breast and ovarian cancers

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists.

30 Nov 2016

Immune System News and Research

Researchers develop new compound that can take down defenses in M. tuberculosis

Experimental T-cell therapy shows promise in preventing AML relapse

Dual therapy safe and effective in patients with recurrent Hodgkin lymphoma

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Research validates effectiveness of world-first dental vaccine

Research unlocks potential new therapies for inflammatory diseases

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

ACS approves $1.7 million funding for new research grants to Yale University

New FDA-approved drug helps patients fight against late-stage lung cancer

Cornell researchers develop chemical probe activated by UV light to control inflammation

Researchers show how microRNAs play key role in tumor progression and response to radiation

Newcastle scientists develop promising new test to identify patients with rare liver disease

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

New UGA research finds pathogen's motility activates immune response

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Study suggests new approach to treat white blood cells of sepsis patients

New device could revolutionize drug delivery to treat cancer and other diseases, study shows

Duke researchers modify popular drug-delivery technology to evade immune responses

Type 2 diabetes drug may someday help combat breast and ovarian cancers

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