Clinical Trial News and Research

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Ruthigen treats first human subjects with leading drug candidate RUT58-60

Ruthigen, Inc., today announced that it has treated the first human subjects with its leading drug candidate RUT58-60 in a 30 patient, 21-day skin irritation trial, which is expected to be completed in August 2014.

17 Jul 2014

Study examines mechanism of bone-protective properties of California dried plums

Fifty-seven million Americans suffer from low bone density or osteoporosis, a disease which causes bones to become so weak and brittle that even a minor fall or other stresses may cause fractures.

17 Jul 2014

Cholesterol-lowering statins may prolong lives of people with diabetic cardiovascular disease

Heart disease and stroke are the leading causes of death and disability among people with Type 2 diabetes. In fact, at least 65 percent of people with diabetes die from some form of heart disease or stroke, according to the American Heart Association.

17 Jul 2014

Rigel initiates Phase 3 clinical program for fostamatinib in patients with ITP

Rigel Pharmaceuticals, Inc. today announced the initiation of a Phase 3 clinical program for its oral SYK inhibitor, fostamatinib, in patients with ITP (immune thrombocytopenic purpura).

16 Jul 2014

Significant percentage of completed drug clinical trials are not disclosed to public

A significant percentage of completed drug clinical trials, especially those funded by industry, are not disclosed to the public, years after being completed-a trend that "threatens the validity of the clinical research literature in the U.S.," according to a study led by a Boston University School of Public Health (BUSPH) researcher.

16 Jul 2014

Tamoxifen gel stops breast cancer growth without causing dangerous side effects

A gel form of tamoxifen applied to the breasts of women with noninvasive breast cancer reduced the growth of cancer cells to the same degree as the drug taken in oral form but with fewer side effects that deter some women from taking it, according to new Northwestern Medicine- research.

16 Jul 2014

Urge incontinence therapy may relieve stress incontinence

Anticholinergic medication appears to be effective as a treatment for stress and mixed urinary incontinence, results of a small clinical trial indicate.

15 Jul 2014

B vitamins do not prevent Alzheimer's disease

Taking B vitamins doesn't slow mental decline as we age, nor is it likely to prevent Alzheimer's disease, conclude Oxford University researchers who have assembled all the best clinical trial data involving 22,000 people to offer a final answer on this debate.

15 Jul 2014

Study pinpoints molecular cause of cachexia, hints at a potential treatment

New research raises the prospect of more effective treatments for cachexia, a profound wasting of fat and muscle occurring in about half of all cancer patients, raising their risk of death, according to scientists from Dana-Farber Cancer Institute.

14 Jul 2014

Noninvasive optical imaging device helps to detect changes linked with Alzheimer's disease

A noninvasive optical imaging device developed at Cedars-Sinai can provide early detection of changes that later occur in the brain and are a classic sign of Alzheimer's disease, according to preliminary results from investigators conducting a clinical trial in Australia.

14 Jul 2014

Young adults reduce binge drinking after receiving text messages following visit to ER

Young adults who screened positive for a history of hazardous or binge drinking reduced their binge drinking by more than 50 percent after receiving mobile phone text messages following a visit to the emergency department, according to a study published online yesterday in Annals of Emergency Medicine ("A Text Message Alcohol Intervention for Young Adult Emergency Department Patients: A Randomized Clinical Trial").

14 Jul 2014

Cataract surgery for people with dementia slows cognition decline, improves quality of life

Cataract surgery for people with Alzheimer's disease and other dementias not only improves vision but can slow decline in cognition and improve quality of life for both people with the disease and their caregivers, according to clinical trial results reported today at the Alzheimer's Association International Conference 2014 (AAIC 2014) in Copenhagen.

13 Jul 2014

Veran announces positive, final results for initial study of SPiNPerc procedure

Veran Medical Technologies, a U.S. based medical device company, announced today the positive, cost-effective final results for the initial study of its innovative SPiNPerc procedure.

11 Jul 2014

HIV detected in Mississippi baby after apparent cure

In November 2013, it was reported that an infant (known as the “Mississippi baby”) had been in prolonged remission from HIV and was apparently cured. However, after 2 years without taking antiretroviral therapy and having no evidence of the virus, the child now has detectable levels of HIV.

11 Jul 2014

Use of electronic health records simplifies clinical trials

Using electronic health records to understand the best available treatment for patients, from a range of possible options, is more efficient and less costly for taxpayers than the existing clinical trial process, a new study shows.

From The University of Manchester 11 Jul 2014

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

The child known as the "Mississippi baby"-an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in The New England Journal of Medicine last fall-now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case.

11 Jul 2014

Baxter International acquires drug candidate developed to treat sickle cell disease

A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business.

11 Jul 2014

Reducing amount of alcoholic beverages consumed may improve cardiovascular health

Reducing the amount of alcoholic beverages consumed, even for light-to-moderate drinkers, may improve cardiovascular health, including a reduced risk of coronary heart disease, lower body mass index (BMI) and blood pressure, according to a new multi-center study published in The BMJ and co-led by the Perelman School of Medicine at the University of Pennsylvania.

11 Jul 2014

New knowledge may expand treatments for patients with lung cancer

Studying the most common type of lung cancer, researchers have uncovered mutations in a cell-signaling pathway that plays a role in forming tumors.

10 Jul 2014

Trial to evaluate safety of FRED- flow diversion system for treatment of aneurysms

After Susan Wakulich was told she had an aneurysm, she figured an invasive brain surgery and lengthy recovery lay ahead of her.

10 Jul 2014

Clinical Trial News and Research

Ruthigen treats first human subjects with leading drug candidate RUT58-60

Study examines mechanism of bone-protective properties of California dried plums

Cholesterol-lowering statins may prolong lives of people with diabetic cardiovascular disease

Rigel initiates Phase 3 clinical program for fostamatinib in patients with ITP

Significant percentage of completed drug clinical trials are not disclosed to public

Tamoxifen gel stops breast cancer growth without causing dangerous side effects

Urge incontinence therapy may relieve stress incontinence

B vitamins do not prevent Alzheimer's disease

Study pinpoints molecular cause of cachexia, hints at a potential treatment

Noninvasive optical imaging device helps to detect changes linked with Alzheimer's disease

Young adults reduce binge drinking after receiving text messages following visit to ER

Cataract surgery for people with dementia slows cognition decline, improves quality of life

Veran announces positive, final results for initial study of SPiNPerc procedure

HIV detected in Mississippi baby after apparent cure

Use of electronic health records simplifies clinical trials

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

Baxter International acquires drug candidate developed to treat sickle cell disease

Reducing amount of alcoholic beverages consumed may improve cardiovascular health

New knowledge may expand treatments for patients with lung cancer

Trial to evaluate safety of FRED- flow diversion system for treatment of aneurysms

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