Protein C News and Research

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Study suggests rattlesnake venom peptide inhibits SARS-CoV-2 replication and transcription

New research suggests a small cationic peptide known as crotamine may inhibit the replication and transcription of SARS-CoV-2.

12 Nov 2021

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Researchers from the US recently reported the preclinical development of a self-amplifying mRNA (SAM) vaccine that encodes a prefusion-stabilized SARS-CoV-2 spike glycoprotein.

12 Nov 2021

Impact of mutations on binding affinity of SARS-CoV-2 variants with ACE2 and existing antibodies

Researchers explained their analysis of the mechanisms that trigger the docking of SARS-CoV-2 variants to ACE2 and the antibodies, referred to as protein-protein docking.

12 Nov 2021

Regular blood tests can identify prostate cancer patients who are resistant to treatment

Regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel, according to research presented at the NCRI Festival.

11 Nov 2021

New treatment for myocardial infarction using mussel adhesive proteins

Patients not only have to fight their diseases but also must deal with the pain – the more severe the condition, the more painful the injections.

11 Nov 2021

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

A team of scientists describe the safety and response to REGEN-COV® for COVID-19 patients with immunodeficiency-associated antibody disorders.

11 Nov 2021

New study offers genetic insight into why we look the way we do

Which genes control the defining features that make us look as we do? And how do they make it happen?

11 Nov 2021

Protein in the blood could predict type 2 diabetes many years before diagnosis

A large study led by Lund University in Sweden has identified a protein in the blood that could predict type 2 diabetes up to nineteen years before the onset of the disease.

11 Nov 2021

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

Researchers have been investigating which other proteins remain prevalent long enough for tests against them to be worthwhile.

11 Nov 2021

New Delta sublineage shows no additional resistance to neutralization

Researchers are attempting to determine the ability of this new sublineage to avoid neutralization by antibodies elicited from vaccination.

11 Nov 2021

Immunity following COVID-19 vaccination and natural infection in India

The researchers evaluated immune response markers in a cross-section of people from the Indian state of West Bengal, including those vaccinated with either Covishield or Covaxin, the unvaccinated cohort, and the naturally infected.

11 Nov 2021

Phage-like particle system provides a platform for quick and easy vaccine generation

In this study, researchers report on the development of a monovalent lambda PLP-based vaccine against SARS-CoV-2 or MERS-Cov through decoration with the spike RBD proteins from either virus.

11 Nov 2021

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

In an attempt to study the safety and effectiveness of sotrovimab in more vulnerable patients suffering from mild to moderate symptoms of COVID-19, a multinational team of researchers conducted the COVID-19 Monoclonal antibody Efficacy Trial-Intent to Care Early (COMET-ICE) trial.

11 Nov 2021

New target for drug development could fill a major gap in depression treatment

Vanderbilt researchers found that ketamine's rapid antidepressant action is due to specific synaptic effects.

10 Nov 2021

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

A paper published in the open-access journal Viruses, reports on a study investigating long-term changes to soluble inflammatory factors and cellular immune phenotype and function in 22 survivors of mild SARS-CoV-2 infection. The observations were then compared to 11 individuals who had recovered from other mild respiratory infections.

10 Nov 2021

New discovery could lead to the creation of a pan-coronaviruses vaccine

Next generation vaccines for Covid-19 should aim to induce an immune response against 'replication proteins', essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists.

10 Nov 2021

Researchers discover mechanisms underlying the unwanted side effects of drugs

Researchers at Weill Cornell Medicine have discovered how drugs can affect various membrane-spanning proteins in addition to their intended target, potentially causing unwanted side effects.

10 Nov 2021

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

A German case study recently published in the journal Nature Communications has characterized a long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection dynamics in an immunosuppressed kidney transplant recipient and provided evidence for the evolution of SARS-CoV-2 into potentially harmful immune escape mutants during persistent infections.

10 Nov 2021

Protein C News and Research

Study suggests rattlesnake venom peptide inhibits SARS-CoV-2 replication and transcription

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Impact of mutations on binding affinity of SARS-CoV-2 variants with ACE2 and existing antibodies

Regular blood tests can identify prostate cancer patients who are resistant to treatment

New treatment for myocardial infarction using mussel adhesive proteins

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

New study offers genetic insight into why we look the way we do

Protein in the blood could predict type 2 diabetes many years before diagnosis

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

New Delta sublineage shows no additional resistance to neutralization

Immunity following COVID-19 vaccination and natural infection in India

Phage-like particle system provides a platform for quick and easy vaccine generation

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

New target for drug development could fill a major gap in depression treatment

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

New discovery could lead to the creation of a pan-coronaviruses vaccine

Researchers discover mechanisms underlying the unwanted side effects of drugs

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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