Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

In silico screening of natural ACE2 inhibitors

Researchers identify potential ACE2 inhibitors through a virtual screening protocol.

14 Mar 2022

Study may provide insight into the evolution of D-amino acid function in marine invertebrates

Amino acids are the basic building blocks of living organisms and typically occur in a configuration known as the L-form. However, there are a few exceptional examples of the structural mirror image of the L-form (known as the D-form) being present in animals.

11 Mar 2022

Potent pan-β-CoV human monoclonal antibody has in vivo activity in multiple animal models

Researchers evaluated the efficacy of viral spike domain 2-specific human monoclonal antibodies delivered intranasally, against all beta coronaviruses in hamsters and mice.

11 Mar 2022

Study shows competitive fitness of emerging SARS-CoV-2 variants linked to their distinctiveness relative to identified lineages

Researchers defined a novel polynucleotide-based Distinctiveness metric to capture the proteome-level differences of emerging SARS-CoV-2 variants and lineages against all previously identified ones.

11 Mar 2022

Researchers solve the structure of large signaling protein involved in emergence of blood cancers

Researchers led by Christopher Garcia of the Ludwig Center at Stanford University have solved the long-sought structure of a large signaling protein involved in responses to infection, inflammation, the generation of immune cells and when dysregulated by mutation - the emergence of blood cancers known as myeloproliferative neoplasms.

11 Mar 2022

Origins and evolutions of SARS-CoV-2 Alpha variant in the UK

In a new study, researchers presented the origins and evolution of the SARS-CoV-2 lineage B.1.1.7 in the United Kingdom.

10 Mar 2022

Quantification of hydrophobic interactions encoded by FP1 sequences of SARS-CoV-2 and MERS-CoV by single-molecule force measurements

Researchers quantified hydrophobic interactions encoded by fusion peptide 1 sequences of SARS-CoV-2 and MERS-CoV using single-molecule force measurements.

10 Mar 2022

The relationship between highly conserved residues in the SARS CoV fusion peptide and their role in coordinating calcium binding for viral entry

Researchers evidenced the significance of calcium in mediating the interaction between the coronaviruses fusion peptide and host cell membrane to provide insights into the mechanisms of viral entry.

9 Mar 2022

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

In a recent study posted to the bioRxiv* preprint server, researchers presented the intragenomic rearrangements of β-coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

9 Mar 2022

How will mutations change the SARS-CoV-2 spike protein in the future?

A new Cells review discusses the factors that affect the function of the SARS-CoV-2 S protein and provides theoretical limits of this viral protein.

8 Mar 2022

Recurrent mutations across the SARS-CoV-2 genome associated with long-term infections in immunodeficient patients

Researchers identified recurrent mutations in SARS-CoV-2.

8 Mar 2022

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

In a recent study posted to the medRxiv*preprint server, a team of researchers from Israel developed and validated novel reverse transcriptase - quantitative polymerase chain reaction (RT-qPCR) assays. The new assays enable the rapid and high throughput identification and differentiation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 variants.

8 Mar 2022

Cell-hobbling fibrils found across diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

4 Mar 2022

Amino Acid News and Research

Further Reading

In silico screening of natural ACE2 inhibitors

Study may provide insight into the evolution of D-amino acid function in marine invertebrates

Potent pan-β-CoV human monoclonal antibody has in vivo activity in multiple animal models

Study shows competitive fitness of emerging SARS-CoV-2 variants linked to their distinctiveness relative to identified lineages

Researchers solve the structure of large signaling protein involved in emergence of blood cancers

Origins and evolutions of SARS-CoV-2 Alpha variant in the UK

Quantification of hydrophobic interactions encoded by FP1 sequences of SARS-CoV-2 and MERS-CoV by single-molecule force measurements

The relationship between highly conserved residues in the SARS CoV fusion peptide and their role in coordinating calcium binding for viral entry

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

How will mutations change the SARS-CoV-2 spike protein in the future?

Recurrent mutations across the SARS-CoV-2 genome associated with long-term infections in immunodeficient patients

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

Cell-hobbling fibrils found across diverse neurodegenerative diseases

Patterns of bat β-coronaviruses evolution

Australian bull ants' venom component exploits a pain pathway in mammals

Understanding the evolutionary mutational patterns of chronic SARS-CoV-2 infection

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Novel coronavirus identified in Swedish bank voles

Biophysical fitness profile of SARS-CoV-2 Delta variant

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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