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Penn-CHOP Kidney Innovation Center focuses on early detection, prevention, and treatment of kidney disease

In an effort to improve the lives of children and adults with kidney disease, Children's Hospital of Philadelphia and Penn Medicine are jointly launching the Penn-CHOP Kidney Innovation Center.

26 Aug 2022

Study explores a potential new therapeutic approach for triple negative breast cancer treatment

Researchers are exploring a potential new therapeutic approach for triple negative breast cancer treatment.

26 Aug 2022

Common molecular tool for DNA labelling shows unexpected anticancer properties

Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

23 Aug 2022

Researchers visualize antigen-bound T-cell receptor at atomic resolution

T cells are our immune system’s customized tools for fighting infectious diseases and tumor cells. On their surface, these special white blood cells carry a receptor that recognizes antigens.

18 Aug 2022

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

Antiviral drugs in combination with antibody therapies could help protect people from the flu pandemic

Researchers at McMaster University have found a class of well-known antiviral drugs could be part of a one-two punch to treat seasonal influenza and prevent a flu pandemic when used in combination with antibody therapies.

16 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Refined analysis method provides new insights into the dominance transition of Omicron sublineages

Researchers at Karolinska Institutet in Sweden present the results of a refined clinical COVID-19 test, which has been used to track the spread of the Omicron variant in real time in the Swedish population.

10 Aug 2022

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molecules.

9 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Yale researchers discover molecular mechanism behind growth of the nervous system

Our nervous system is composed of billions of neurons that speak to each other through their axons and dendrites.

8 Aug 2022

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

University of California, Irvine researchers have developed a COVID-19 test that detects and identifies specific SARS-CoV-2 variants with 100% accuracy.

3 Aug 2022

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

A recent study published in the Journal of Food Biochemistry discovered that peimine from Fritillaria might be a possible SARS-CoV-2 variant infection inhibitor.

2 Aug 2022

Würzburg scientists are working on the development of new drugs to combat monkeypox

Poxviruses pose a threat to humanity that should be taken seriously, as the current outbreak of monkeypox shows.

1 Aug 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Researchers report near-atomic-resolution images of nitrogenase during catalysis using cryo-EM

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action.

29 Jul 2022

An enzyme may be a potent new tool for reducing nitrous oxide in the atmosphere

An enzyme that combats the greenhouse gas nitrous oxide (N2O) may one day give scientists a potent new tool for reducing the amount of the gas in the atmosphere thanks in part to new findings published today in Nature.

28 Jul 2022

Phage therapeutics can be used to fight multidrug-resistant pathogens

Scientists with the Texas A&M College of Agriculture and Life Sciences were among those providing the biochemical tools needed to help save a man's life through a unique emergency intervention in 2016.

27 Jul 2022

Researchers unravel how one gut bacterium influences immunity

From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease.

27 Jul 2022

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant.

26 Jul 2022