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Exposure to flame retardant impacts paternal reproduction

A new study from the University of Georgia has shown that exposure to a now-banned flame retardant can alter the genetic code in sperm, leading to major health defects in children of exposed parents.

9 Jun 2020

Innovative algorithm helps select patients in need of urgent surgery or chemotherapy during COVID-19

A new approach to better select breast cancer patients in need of urgent surgery or chemotherapy during the COVID-19 pandemic has been developed by researchers at The Royal Marsden and the Breast Cancer Now Research Centre at The Institute of Cancer Research, London, in collaboration with colleagues in the UK, Germany and US.

8 Jun 2020

New guidance for healthcare providers caring for hospitalized COVID-19 patients with diabetes

The COVID-19 pandemic presents new challenges for clinicians caring for infected patients with diabetes, according to new guidance published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Jun 2020

Newer data confirms survival advantages, but also side effects for ribociclib in breast cancer

In 2017 and 2019, the German Institute for Quality and Efficiency in Health Care had already examined the advantages and disadvantages of ribociclib in combination with an aromatase inhibitor or fulvestrant in comparison with the appropriate comparator therapy in patients after menopause, with hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer.

5 Jun 2020

Update on PALLAS triaI evaluating adjuvant palbociclib for early breast cancer

The Austrian Breast & Colorectal Cancer Study Group, Alliance Foundation Trials, the Breast International Group, PrECOG, LLC, the German Breast Group, and the NSABP Foundation today announced that the independent Data Monitoring Committee for the global Phase 3 early breast cancer PALbociclib CoLlaborative Adjuvant Study trial determined that the study is unlikely to show a statistically significant improvement in the primary endpoint of invasive disease-free survival following a preplanned interim analysis.

1 Jun 2020

How COVID-19 affects the nervous system

A new paper published in the journal JAMA Neurology in May 2020 discusses the presentation and complications of COVID-19 with respect to the nervous system.

31 May 2020

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW trial, led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Study reports COVID-19 case-fatality trends among people with IDD

A new study published recently in ScienceDirect by researchers from Syracuse University and SUNY Upstate Medical University shows that people with intellectual and developmental disabilities (IDD) are more likely to die from COVID-19 than those without IDD.

28 May 2020

UTSW/Children's Health joint program approved as Certified Duchenne Care Center

A joint program of UT Southwestern Medical Center and Children's Health has been approved as a Certified Duchenne Care Center by Parent Project Muscular Dystrophy, the nation's most comprehensive nonprofit organization focused on finding a cure for Duchenne muscular dystrophy.

27 May 2020

New book series brings updated reviews on diabetes and obesity

Frontiers in Clinical Drug Research - Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases - diabetes and obesity.

27 May 2020

Study uncovers the role of DNA repair in preserving egg quality

A Monash University study has uncovered the role DNA repair plays in preserving egg quality, offering hope for women whose eggs may be damaged through treatments such as radiation and chemotherapy.

22 May 2020

Environmental chemicals linked to changes in the gut microbiome and health

The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants.

21 May 2020

Study: COVID-19 infection may cause subacute thyroiditis

COVID-19 infection may cause subacute thyroiditis, according to a new case study published in The Journal of Clinical Endocrinology & Metabolism.

21 May 2020

Cancer biologists identify important drivers of tumor resistance

Cancer biologists at the Mays Cancer Center, home to UT Health San Antonio MD Anderson, have identified important drivers that enable tumors to change their behavior and evade anticancer therapies.

18 May 2020

U.S. physician survey highlights impact and burden of Thyroid Eye Disease on patients’ quality of life

Horizon Therapeutics plc today announced results of a U.S. physician survey showing that endocrinologists and ophthalmologists perceive Thyroid Eye Disease to have a significant burden on their patients’ quality of life.

13 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

Scientists discover new metabolism regulation system for the brown adipose tissue

Scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes.

8 May 2020

New guidance released for treating patients with osteoporosis during COVID-19 crisis

The Endocrine Society joined a coalition of leading bone health organizations to release guidance for healthcare professionals treating patients with osteoporosis in the era of COVID-19.

8 May 2020

Harmful effects of BPA can be reversed by administering coenzyme Q10

Exposure to bisphenol A (BPA), an industrial chemical used to make certain plastics and resins, inner coatings for food cans and bottle tops, thermal paper used in store receipts, dental sealants and so on, is a concern because of possible adverse health effects, including a reduction in fertility.

7 May 2020

Study can serve as basis for developing new approaches for obesity, diabetes

In the 21st century, the search for methods of treating noncommunicable diseases, such as obesity, metabolic syndrome, and diabetes are among the top priorities.

24 Apr 2020