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What does COVID-19 do to the body?

The novel coronavirus SARS-CoV-2, also known as 2019-nCoV, is the virus that causes COVID-19, and that is spreading throughout the world is causing panic in almost all countries. With a death rate ranging from 1% to 2% in young patients but about 5%-8% in elderly and sick patients, it is capable of ravaging multiple organ systems in the human body.

12 Mar 2020

Fruit flies provide insight on ACOX1-related neurodegenerative disorders

A study led by researchers at Baylor College of Medicine reports that a hyperactive variant of enzyme ACOX1 produces elevated levels of toxic reactive oxygen species (ROS) and causes a previously unidentified late-onset neurodegenerative disorder.

12 Mar 2020

Potential breakthrough in cancer immunotherapy with gasdermin E

A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present.

11 Mar 2020

Research reveals key role of a protein in rare Batten disease

Professor Stéphane Lefrançois, a researcher at the Institut National de la Recherche Scientifique (INRS), is working on Batten disease, a neurodegenerative genetic disease that primarily affects children. His research focuses on the most common form of the disease - Batten CLN 3 - which is caused by mutations in the protein of the same name and for which there is still no cure.

28 Feb 2020

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

APEIRON Biologics AG, a biotechnology company with an approved product on the market as well as a broad preclinical and clinical pipeline, today announced the launch of a Pilot investigator-initiated clinical trial with APN01, a recombinant human angiotensin-converting enzyme 2, to treat patients with severe coronavirus infection in the People's Republic of China.

26 Feb 2020

Supplementing diet with amino acid delays signs of ALS in animal study

The addition of dietary L-serine, a naturally occurring amino acid necessary for formation of proteins and nerve cells, delayed signs of amyotrophic lateral sclerosis in an animal study.

24 Feb 2020

Two new grants will help researchers to study neurotechnology, drug delivery system

Two grants will fund interdisciplinary research at the Beckman Institute for Advanced Science and Technology, including a look at how neurons and muscle cells communicate with each other and also to develop a drug delivery system for treatment of Alzheimer's disease.

23 Feb 2020

New study expands the knowledge on tumor-suppressor role of HERC proteins

The RAF protein could be a therapeutical target to treat the tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine and Health Sciences of the University of Barcelona and the Bellvitge Institute for Biomedical Research.

20 Feb 2020

Neuronal necrosis occurs much earlier in Alzheimer’s disease progression than previously thought

Alzheimer's remains the leading cause of dementia in Western societies, with some estimates suggesting that as many as 24 million people worldwide are living with the disease.

13 Feb 2020

Study reveals molecular pathogenesis of muscular dystrophy-associated cardiomyopathy

In a study recently published in Nature Communications scientists at Okayama University describe the detailed molecular pathogenesis of muscular dystrophy-associated cardiomyopathy in mice lacking the fukutin gene (Fktn), the causative gene for Fukuyama muscular dystrophy.

13 Feb 2020

New therapeutic strategy to fight against advanced melanoma

Scientists from the Centenary Institute have developed a new therapeutic strategy that could potentially help the fight against advanced-stage melanoma.

29 Jan 2020

Rushing into intense exercise after a break can cause “rhabdo”, potentially leading to kidney injury

New evidence is coming to light warning people from rushing too quickly into intense exercise.

27 Jan 2020

Halting metastasis by preventing cancer cells from using fat

Healthy cells normally undergo cell division, but when a genetic mutation causes uncontrolled cell growth, they form a tumor. Cancer is one of the leading causes of death worldwide, and most deaths happen when cancer cells start to metastasize or travel from the mother tumor to other parts of the body.

23 Jan 2020

Reelin can reverse the main pathological processes associated with Alzheimer's, other tauopathies

Promoting the signaling pathway of reelin -an essential extracellular protein for the neuronal migration and synaptic plasticity- could be an effective therapeutical strategy to counterbalance the main cognitive, biochemical and behavioral alterations seen in Alzheimer's and other pathologies associated with Tau protein, as shown in a new study with animal models -published in the journal Progress in Neurobiology.

23 Jan 2020

Breakthrough discovery could lead to more effective immunotherapies

Scientists at UCL have discovered how immune cells, essential for tackling life-threatening infections and cancers, are able to 'recycle' material within themselves in order to stay healthy and function, a breakthrough finding which could lead to more effective immunotherapies.

21 Jan 2020

Intracellular News and Research

What does COVID-19 do to the body?

Fruit flies provide insight on ACOX1-related neurodegenerative disorders

Potential breakthrough in cancer immunotherapy with gasdermin E

Research reveals key role of a protein in rare Batten disease

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

Supplementing diet with amino acid delays signs of ALS in animal study

Two new grants will help researchers to study neurotechnology, drug delivery system

New study expands the knowledge on tumor-suppressor role of HERC proteins

Neuronal necrosis occurs much earlier in Alzheimer’s disease progression than previously thought

Study reveals molecular pathogenesis of muscular dystrophy-associated cardiomyopathy

New therapeutic strategy to fight against advanced melanoma

Rushing into intense exercise after a break can cause “rhabdo”, potentially leading to kidney injury

Halting metastasis by preventing cancer cells from using fat

Reelin can reverse the main pathological processes associated with Alzheimer's, other tauopathies

Breakthrough discovery could lead to more effective immunotherapies

Researchers develop self-assembled artificial microtubule like LEGO building blocks

Inexpensive drug may be used to counteract treatment resistance in patients with leukemia

Study shows superior functionality of Duodenum Intestine-Chip populated with organoids

Scientists gain insights into structure and interactions of EGF receptors

Certain bacteria can override programmed cell death

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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