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Canadian study links ultra processed foods to poor health outcomes

A landmark study exploring Canadians' consumption of chips, frozen pizzas, breakfast cereals and other ultra-processed foods typically loaded with fat, sugar and additives has confirmed these foods are directly and significantly linked to poor health outcomes.

7 May 2025

New predictive algorithms improve early detection of undiagnosed cancers

Two new advanced predictive algorithms use information about a person's health conditions and simple blood tests to accurately predict a patient's chances of having a currently undiagnosed cancer, including hard to diagnose liver and oral cancers.

7 May 2025

Gastrointestinal cancer patterns vary across diverse Asian and Pacific Islander populations

The incidence of gastrointestinal cancers varies across Asian American, Native Hawaiian and other Pacific Islander communities, according to a study published March 15 in the journal Gastro Hep Advances.

7 May 2025

Study: Kissing after a gluten-filled snack is safe for people with celiac disease

People with celiac disease have reported anxiety about ingesting gluten through a kiss, but a new study concludes that they can indulge without worry - even if their partner just had a gluten-filled snack, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025

New rifamycin drugs fight antibiotic-resistant lung infections more effectively

Researchers have developed next-generation rifamycin analogs that effectively kill both replicating and nonreplicating Mycobacterium abscessus while minimizing drug-drug interactions. Lead candidates UMN-120 and UMN-121 showed superior efficacy to current treatments in mouse models and retained potency against M. tuberculosis.

5 May 2025

TM6SF2 gut-specific knockout aggravates liver lipid accumulation in MASLD mice

Metabolic dysfunction-associated steatotic liver disease (MASLD), is the most common form of chronic liver disease worldwide. This study aimed to explore the role of TM6SF2 in high-fat diet (HFD)-induced MASLD through the gut-liver axis.

5 May 2025

Anal cancer rates increasing among older white and Hispanic women in the U.S.

Anal cancer has been steadily increasing in the United States, with the biggest jumps among older women, especially white and Hispanic women - a shift that challenges assumptions about high-risk groups and who should be screened, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025

Early detection of stomach cancer shows major progress

Stomach cancers are increasingly being diagnosed at less advanced, more treatable stages - a shift that marks major progress in detecting one of the deadliest forms of cancer, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025

Low income linked to higher risk of dying from liver cancer

The risk of dying from the most common form of primary liver cancer is about 30 percent higher for patients with low household income compared to those with middle or high household income, according to a study at the University of Gothenburg.

5 May 2025

Semaglutide clears liver inflammation and cuts fibrosis in MASH patients, trial shows

A phase 3 trial shows that once-weekly semaglutide significantly improves liver histology in patients with metabolic dysfunction-associated steatohepatitis (MASH). The interim results also reveal meaningful weight loss and improved cardiometabolic markers, with a favorable safety profile.

4 May 2025

Black coffee improves insulin sensitivity in women, study finds

Two daily cups of coffee, especially black, are linked to lower insulin resistance and fasting insulin levels in Korean women, suggesting coffee may improve glucose metabolism. The effect was not observed with coffee containing sugar or cream.

4 May 2025

Study shows brain estrogen directly regulates appetite in mice

Researchers in Japan found that estrogen produced within the brain, called neuroestrogen, suppresses appetite and reduces body weight in mice by enhancing MC4R expression. The study also showed that neuroestrogen boosts leptin sensitivity, suggesting new targets for obesity treatment.

2 May 2025

HO-1 regulates liver fibrosis in NAFLD through the SIRT1 TGF-β Smad3 pathway

Heme oxygenase 1 (HO-1) has an influential yet insufficiently investigated effect on Sirtuin 1 (SIRT1), a histone deacetylase activated by nicotinamide adenine dinucleotide, which may impact the transforming growth factor-β (TGF-ß)/Smad3 pathway in nonalcoholic fatty liver disease (NAFLD)-related liver fibrosis.

2 May 2025

Study: One in four early cardiogenic shock patients experience worse outcomes

In one of the largest studies of early cardiogenic shock (CS) patients, where blood flow is still functioning to vital organs, researchers demonstrated that 26% experienced worse outcomes, including care escalation, CS deterioration, or in-hospital mortality.

2 May 2025

High fructose diets impair brain function and appetite control, study shows

Review highlights how excessive fructose intake disrupts brain energy balance, appetite regulation, and cognitive function. Processed sources, such as sugary drinks, may overwhelm metabolic pathways and induce neuroinflammation, particularly during adolescence.

30 Apr 2025

Higher biological age linked to increased dementia risk

People whose biological age is higher than their chronological age may be more likely to develop dementia than people whose biological age matches or is lower than their chronological age, according to a study published on April 30, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

30 Apr 2025