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SARS-CoV-2 anti-N rigid monoclonal antibodies provide accurate early diagnosis

An interesting new preprint research paper that was posted on the bioRxiv* server recently describes the use of rigid monoclonal antibodies (mAbs) in contrast to flexible mAbs, and how this affects the binding of multiple mAbs to the same antigen.

17 Jan 2021

Scientists discover new treatment target for osteoarthritis-like knee cartilage degeneration

There is currently no cure for osteoarthritis, but a group of scientists believe they've discovered a method through which a simple knee injection could potentially stop the disease's effects.

16 Jan 2021

New nasal spray delivers antipsychotic medication directly to the brain

A team of neuroscientists and engineers at McMaster University has created a nasal spray to deliver antipsychotic medication directly to the brain instead of having it pass through the body.

16 Jan 2021

Avalanching nanoparticles may advance real-time bioimaging of cell's organelles and proteins

Since the earliest microscopes, scientists have been on a quest to build instruments with finer and finer resolution to image a cell's proteins - the tiny machines that keep cells, and us, running.

14 Jan 2021

New technology could protect against different coronavirus variants

The SARS-CoV-2 virus that is causing the COVID-19 pandemic is just one of many different viruses in the coronavirus family.

13 Jan 2021

Boosting a natural cellular process could lower ventilator-related lung damage

An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage.

12 Jan 2021

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.

12 Jan 2021

NIST compiles the first detailed tutorial on DNA origami

In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers.

8 Jan 2021

Single-dose nanoparticle vaccine for SARS-CoV-2

Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza.

8 Jan 2021

Single-dose nanoparticle COVID-19 vaccine elicits virus-neutralizing antibody response in mice

Across the world, health care workers and high-risk groups are beginning to receive COVID-19 vaccines, offering hope for a return to normalcy amidst the pandemic.

8 Jan 2021

MSU researchers show how microbes could soak up toxic pollutants

When Michigan State University's Gemma Reguera first proposed her new research project to the National Science Foundation, one grant reviewer responded that the idea was not "environmentally relevant."

8 Jan 2021

Surface-textured nanocrystals for biofilm eradication

The COVID-19 pandemic is raising fears of new pathogens such as new viruses or drug-resistant bacteria.

8 Jan 2021

Heat treatment during chemotherapy is more effective at destroying cancer cells

Heating up cancer cells while targeting them with chemotherapy is a highly effective way of killing them, according to a new study led by UCL researchers.

5 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Could engineered red blood cells be an effective antiviral against SARS-CoV-2?

In a new study, released on the bioRxiv* preprint server, a team of researchers explores the antiviral potential of red blood cells against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19.

24 Dec 2020

Researchers review future directions of nanomedicine development

Announcing a new publication for BIO Integration journal. In this commentary the authors Phei Er Saw and Sangyong Jon from Sun Yat-Sen University, Guangzhou, China and the Korea Advanced Institute of Science and Technology, Daejeon, Korea, consider how the entry mechanism of nanoparticles into tumors determines the future direction of nanomedicine development.

24 Dec 2020

Anti-diarrhea drug triggers cell death in glioblastoma cells

In cell culture, loperamide, a drug commonly used against diarrhea, proves effective against glioblastoma cells. A research team at Goethe University has now unraveled the drug’s mechanisms of action of cell death induction and – in doing so – has shown how this compound could help attack brain tumors that otherwise are difficult to treat.

22 Dec 2020